[hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(7-oxo-3,4-dihydro-1H-pyrimido[4,5-c]oxazin-6-yl)oxolan-2-yl]methoxy]phosphoryl] phosphono hydrogen phosphate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: [hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(7-oxo-3,4-dihydro-1H-pyrimido[4,5-c]oxazin-6-yl)oxolan-2-yl]methoxy]phosphoryl] phosphono hydrogen phosphate
• 化学式: C₁₁H₁₈N₃O₁₄P₃
• 分子量: 509.19
• InChiKey: VIEAOJCAIOZBPW-DJLDLDEBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5
• 重原子数：
  31
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  243
• 氢给体数：
  6
• 氢受体数：
  14

文献信息

• Method for sequence analysis
  申请人：——

  公开号：US20040152108A1

  公开（公告）日：2004-08-05

  The present invention is directed to the use of at least one secondary subunit sequence that varies from a primary subunit sequence by the addition, deletion and/or substitution of at least one subunit for inferring information about the primary subunit sequence. The invention is also directed to the use of such variant sequences for wholly or partially executing a task on an primary subunit sequence, which in one embodiment is refractory to the execution of that task and more particularly to the use of such sequence(s) for wholly or partially deducing the sequence of a primary subunit sequence. In a preferred embodiment of the present invention, the variant sequences are generated by mutagenesis techniques. The subject invention further relates to a method, which is optionally implemented by a processing system, for designing secondary subunit sequences. The present invention further extends to a method, which is suitably implemented by a processing system, to a computer program product for comparing subsequences derived from a primary subunit sequence and from at least one secondary subunit sequence to facilitate inference of the primary subunit sequence.

  本发明的目的是使用至少一个次级亚单位序列，该序列通过增加、删除和/或替换至少一个亚单位而与主亚单位序列不同，用于推断有关主亚单位序列的信息。本发明还涉及利用这种变异序列全部或部分执行主亚基序列上的任务，在一个实施方案中，主亚基序列对该任务的执行具有耐受性，更具体地说，本发明涉及利用这种序列全部或部分推断主亚基序列的序列。在本发明的一个优选实施方案中，变异序列是通过诱变技术产生的。本发明进一步涉及一种设计次级亚单位序列的方法，该方法可选择由处理系统实施。本发明进一步涉及一种方法，该方法可选择由处理系统实现，还涉及一种计算机程序产品，用于比较从主亚单位序列和至少一个次级亚单位序列中得到的子序列，以促进对主亚单位序列的推断。