Batrachamine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: Batrachamine
• 英文别名: 2,6-bis(4-aminobutyl)-5-imino-2,6-dihydro-1H-pyrazin-3-amine
• 化学式: C₁₂H₂₆N₆
• 分子量: 254.38
• InChiKey: DYQQHNFSDKKCJO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  18
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  126
• 氢给体数：
  5
• 氢受体数：
  4

文献信息

• Diimino-piperazine derivatives for use as modulators of cell regulation
  申请人：——

  公开号：US20030166666A1

  公开（公告）日：2003-09-04

  Compositions, methods of use, isolation and biosynthesis of diimino-piperazine derivatives useful for the modification of sphingolipid metabolism and other biological functions are described. The preferred derivative is 2,6-bis-(&ohgr;-aminobutyl)-3,5-diimino-piperazine. This is a naturally occurring biochemical compound isolated from cells. The diimino-piperazine derivatives are useful as therapeutic agents when administered to patients to treat diseases and disorders involving cell regulation.

  本文描述了可用于改变鞘脂代谢和其他生物功能的二亚氨基哌嗪衍生物的组成、使用方法、分离和生物合成。首选的衍生物是 2,6-双（&ohgr;-氨基丁基）-3,5-二亚氨基哌嗪。这是一种从细胞中分离出来的天然生化化合物。二亚氨基哌嗪衍生物可用作治疗剂，用于治疗患者的疾病和细胞调节紊乱。
• US6552025B1
  申请人：——

  公开号：US6552025B1

  公开（公告）日：2003-04-22
• US6750211B2
  申请人：——

  公开号：US6750211B2

  公开（公告）日：2004-06-15
• [EN] DIIMINO-PIPERAZINE DERIVATIVES FOR USE AS MODULATORS OF CELL REGULATION<br/>[FR] DERIVES DE LA DIIMINO-PIPERAZINE DESTINES A ETRE UTILISES COMME MODULATEURS DE LA REGULATION CELLULAIRE
  申请人：UNIV EMORY

  公开号：WO2001037836A1

  公开（公告）日：2001-05-31

  Compositions, methods of use, isolation and biosynthesis of diimino-piperazine derivatives useful for the modification of sphingolipid metabolism and other biological functions are described. The preferred derivative is 2,6-bis-(φ-aminobutyl)-3,5-diimino-piperazine. This is a naturally occurring biochemical compound isolated from cells. The diimino-piperazine derivatives are useful as therapeutic agents when administered to patients to treat diseases and disorders involving cell regulation.