(E)-N-(2,6-二甲基苯基)-1-(2-氟苯基)甲亚胺 | 823196-34-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: (E)-N-(2,6-二甲基苯基)-1-(2-氟苯基)甲亚胺
• 英文名称: 2-C6H4F(CH=NC6H3Me2-2,6)
• 英文别名: o-C6H4F(CH=NC6H3Me2-2,6)；(E)-N-(2,6-Dimethylphenyl)-1-(2-fluorophenyl)methanimine；N-(2,6-dimethylphenyl)-1-(2-fluorophenyl)methanimine
• CAS: 823196-34-5
• 化学式: C₁₅H₁₄FN
• 分子量: 227.281
• InChiKey: JXNLJJZZMJKUMD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (E)-N-(2,6-二甲基苯基)-1-(2-氟苯基)甲亚胺 在 正丁基锂 、 zinc(II) chloride 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 48.0h， 生成 dibenzo[b,j][4,7]phenanthroline
  参考文献：
  名称：

  ZnCl 2促进邻芳基氨基苯基希夫碱分子内环化反应轻松合成A啶衍生物

  摘要：

  开发了一种简便易行的方法，该方法可在方便的条件下，通过容易获得的邻芳基氨基苯基席夫碱化合物的ZnCl 2促进的环化反应，合成各种a啶衍生物和多环氮杂芳族化合物。详细研究了该新方法的反应条件和范围。

  DOI：

  10.1021/ol402732n
• 作为产物：
  描述：

  2-氟苯甲醛 、 2,6-二甲基苯胺 以 正己烷 为溶剂， 反应 2.0h， 以78%的产率得到(E)-N-(2,6-二甲基苯基)-1-(2-氟苯基)甲亚胺
  参考文献：
  名称：

  含N、N、S三齿配体的NiII和PdII配合物的合成和表征及其对降冰片烯聚合的催化性能

  摘要：

  一系列新的 N,N,S 三齿镍 (II) 配合物 [(ArN = CHC6H4NPh-2-SPh)NiBr] (Ar = 2,6-二异丙基苯基, 1; Ar = 2,6-二甲基苯基, 2; Ar = Ph, 3) 和钯 (II) 配合物 [(ArN = CHC6H4NPh-2-SPh)PdCH3]（Ar = 2,6-二异丙基苯基，4；Ar = 2,6-二甲基苯基，5；Ar = Ph，6）合成和表征。单晶结构的 X 射线衍射分析表明，三齿配合物 1、2、4、5 和 6 具有中心金属的扭曲方形平面配位。与带有苯胺-亚胺配体的双齿金属配合物相比，N,N,S 三齿金属配合物表现出更好的稳定性。在甲基铝氧烷 (MAO) 的存在下，镍配合物 1-3 在大气压下对乙烯低聚反应显示出中等活性，但钯配合物没有活性。然而，镍配合物表现出高达 8.20 × 106 g/(mol of Ni) h 的高活性，钯配合物对以

  DOI：

  10.1002/ejic.200800468

文献信息

• Nickel complexes bearing N,N,N-tridentate quinolinyl anilido–imine ligands: Synthesis, characterization and catalysis on norbornene addition polymerization
  作者：Zhiqiang Hao、Nan Yang、Wei Gao、Lan Xin、Xuyang Luo、Ying Mu

  DOI：10.1016/j.jorganchem.2013.10.020

  日期：2014.1

  The N,N,N-tridentate quinolinyl anilido–imine ligands 2-(ArNC(H))C6H4–HNC9H6N (LaH, Ar = 2,6-Me2C6H3; LbH, Ar = 2,6-iPr2C6H3) and 2-(C9H6N)NC(H)C6H4–HNAr (LcH, Ar = 2,6-Me2C6H3; LdH, Ar = 2,6-iPr2C6H3) were synthesized and characterized. Reactions of these ligands with nBuLi and subsequent additions of NiCl2(DME) afford the N,N,N-tridentate nickel complexes [2-(ArNC(H))C6H4–NC9H6N]NiCl (Ar = 2,6-Me2C6H3

  的Ñ，Ñ，Ñ -tridentate喹啉基酰苯胺-亚胺配体2-（ArNC（H））C 6 H ^ 4 -HNC 9 ħ 6 N（大号一个ħ中，Ar = 2,6-ME 2 ç 6 ħ 3 ;大号b H，Ar = 2,6- i Pr 2 C 6 H 3）和2-（C 9 H 6 N）NC（H）C 6 H 4 -HNAr（L c H，Ar = 2,6-Me 2 C 6H 3 ; 合成并表征了L d H，Ar = 2,6- i Pr 2 C 6 H 3）。这些配体与n BuLi的反应以及随后添加的NiCl 2（DME）生成N，N，N三齿镍络合物[2-（ArNC（H））C 6 H 4 –NC 9 H 6 N] NiCl（Ar = 2,6-Me 2 C 6 H 3（1a），2,6- i Pr 2 C 6H 3（1b））和[2-（C 9 H 6 N）NC（H）C 6 H 4 –NAr] NiCl（Ar = 2
• Synthesis of Ti, Zr, and Hf complexes with a new tetra-azane ligand by one-pot HCl-elimination and their properties as catalysts for production of UHMWPE
  作者：Xiangdong Ji、Wei Yao、Xuyang Luo、Wei Gao、Ying Mu

  DOI：10.1039/c5nj02151k

  日期：——

  The first example for the HCl-elimination reaction being applied in the attachment of an amido-containing ligand to Zr and Hf.

  HCl-消除反应的第一个例子是将含有氨基配体附着到锆和铪上。
• Chromium(III) Complexes with Chelating Anilido–Imine Ligands: Synthesis, Structures, and Catalytic Properties for Ethylene Polymerization
  作者：Tieqi Xu、Haiyan An、Wei Gao、Ying Mu

  DOI：10.1002/ejic.201000150

  日期：2010.7

  complexes that bear anilido-imine ligands, [(ortho-C 6 H 4 (NAr')(CH=NAr")}CrCl 2 (thf) 2 ] [Ar' = Ar" = C 6 H 5 (1); Ar' = Ar" = p-MeC 6 H 4 (2); Ar' = Ar" = 2,6-Me 2 C 6 H 3 (3); Ar' = 2,6-iPr 2 C 6 H 3 , Ar" = 2,6-Me 2 C 6 H 3 (4); Ar' = Ar" = 2,6-iPr 2 C 6 H 3 (5)], have been synthesized and characterized by elemental analysis, IR spectroscopy, and ESI-MS. The molecular structures of complexes 1 and

  一系列带有苯胺-亚胺配体的新型铬配合物，[(邻位-C 6 H 4 (NAr')(CH=NAr")}CrCl 2 (thf) 2 ] [Ar' = Ar" = C 6 H 5 (1); Ar' = Ar" = p-MeC 6 H 4 (2); Ar' = Ar" = 2,6-Me 2 C 6 H 3 (3); Ar' = 2,6-iPr 2 C 6 H 3 , Ar" = 2,6-Me 2 C 6 H 3 (4); Ar' = Ar" = 2,6-iPr 2 C 6 H 3 (5)]，已合成并通过元素分析表征, IR 光谱和 ESI-MS. 单晶 X 射线衍射分析证实了配合物 1 和 2 的分子结构。当用甲基铝氧烷 (MAO) 活化时，这些配合物对乙烯聚合和生产中等分子量的聚乙烯。
• Synthesis and Characterization of Ni ^II and Pd ^II Complexes Bearing N,N,S Tridentate Ligands and Their Catalytic Properties for Norbornene Polymerization
  作者：Jieming Long、Haiyang Gao、Keming Song、Fengshou Liu、Hao Hu、Ling Zhang、Fangming Zhu、Qing Wu

  DOI：10.1002/ejic.200800468

  日期：2008.9

  bidentate metal complexes bearing anilido–imine ligands, the N,N,S tridentate metal complexes showed better stability. In the presence of methylaluminoxane (MAO), nickel complexes 1–3 showed moderate activity toward ethylene oligomerization at atmosphere pressure, but the palladium complexes were inactive. However, the nickel complexes exhibited high activity up to 8.20 × 106 g/(mol of Ni) h and palladium

  一系列新的 N,N,S 三齿镍 (II) 配合物 [(ArN = CHC6H4NPh-2-SPh)NiBr] (Ar = 2,6-二异丙基苯基, 1; Ar = 2,6-二甲基苯基, 2; Ar = Ph, 3) 和钯 (II) 配合物 [(ArN = CHC6H4NPh-2-SPh)PdCH3]（Ar = 2,6-二异丙基苯基，4；Ar = 2,6-二甲基苯基，5；Ar = Ph，6）合成和表征。单晶结构的 X 射线衍射分析表明，三齿配合物 1、2、4、5 和 6 具有中心金属的扭曲方形平面配位。与带有苯胺-亚胺配体的双齿金属配合物相比，N,N,S 三齿金属配合物表现出更好的稳定性。在甲基铝氧烷 (MAO) 的存在下，镍配合物 1-3 在大气压下对乙烯低聚反应显示出中等活性，但钯配合物没有活性。然而，镍配合物表现出高达 8.20 × 106 g/(mol of Ni) h 的高活性，钯配合物对以
• Al and Zn complexes bearing N,N,N-tridentate quinolinyl anilido-imine ligands: synthesis, characterization and catalysis in l-lactide polymerization
  作者：Nan Yang、Lan Xin、Wei Gao、Jingshun Zhang、Xuyang Luo、Xiaoming Liu、Ying Mu

  DOI：10.1039/c2dt30594a

  日期：——

  Reactions of N,N,N-tridentate quinolinyl anilido-imine ligands with AlMe3 afford mononuclear aluminum complexes κ3-[2-[ArNC(H)]C6H4}N(8-C9H6N)]}AlMe2 (Ar = 2,6-Me2C6H3 (1a), 2,6-Et2C6H3 (1b), 2,6-iPr2C6H3 (1c)) or dinuclear complexes AlMe3κ1-[2-[ArNC(H)C6H4]N(8-C9H6N)}-κ2]AlMe2 (R = 2,6-Me2C6H3 (2a), 2,6-Et2C6H3 (2b), 2,6-iPr2C6H3 (2c)) depending on the ratios of reactants used. Similar reactions of ZnEt2 with these ligands give the monoligated ethyl zinc complexes κ3-[2-[ArNC(H)]C6H4}N(8-C9H6N)]}ZnEt (Ar = 2,6-Me2C6H3 (3a), 2,6-Et2C6H3 (3b), 2,6-iPr2C6H3 (3c)) or bisligated complexes κ3-[2-[ArNC(H)]C6H4}N(8-C9H6N)]}Znκ2-[2-[ArNC(H)]C6H4}N(8-C9H6N)]} (Ar = 2,6-Me2C6H3 (4a), 2,6-Et2C6H3 (4b), 2,6-iPr2C6H3 (4c)). These complexes were well characterized by NMR and the structures of 1a, 2a, 2c, 3b and 4c were confirmed by X-ray diffraction analysis. The aluminum and zinc complexes were tested to initiate lactide polymerization in which the zinc complexes show moderate to high activities in the presence of benzyl alcohol.

  和3c。