potassium N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]-2-phenylethenesulfonamidate | 351019-43-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: potassium N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]-2-phenylethenesulfonamidate
• CAS: 351019-43-7
• 化学式: C₂₅H₂₃N₅O₆S*K
• 分子量: 560.652
• InChiKey: ABNZGJFDMXHARN-KCUXUEJTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.14
• 重原子数：
  38
• 可旋转键数：
  11
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  154
• 氢给体数：
  2
• 氢受体数：
  11

文献信息

• SUBSTITUTED NITROGEN HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL USE THEREOF
  申请人：Ustav Experimentalni Botaniky Akademie ved Ceské Republiky

  公开号：EP1147108A1

  公开（公告）日：2001-10-24
• [EN] SUBSTITUTED NITROGEN HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL USE THEREOF<br/>[FR] DERIVES HETEROCYCLIQUES D'AZOTE SUBSTITUE ET LEUR UTILISATION PHARMACEUTIQUE
  申请人：USTAV EX BOTAN AKADEMIE VED CE

  公开号：WO2000043394A1

  公开（公告）日：2000-07-27

  This invention relates to new substituted nitrogen heterocyclic derivatives having cytostatic, anticancer, antimitotic, antineurogenerative, immunosuppressive and antimicrobial effects. This invention also relates to the methods for preparation of these derivatives, the use of the compounds as drugs, the pharmaceutical composition and combined pharmaceutical application form comprising an effective dose of a claimed compound and the use of these derivatives for drug production.