P-P-P-dUrd-biotinyl

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷酸
• 英文名称: P-P-P-dUrd-biotinyl
• 英文别名: [(2R,3S,5R)-5-(2,4-dioxopyrimidin-1-yl)-2-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]oxolan-3-yl] 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate
• 化学式: C₁₉H₂₉N₄O₁₆P₃S
• 分子量: 694.4
• InChiKey: XYCDFLZYMIUTDO-OJFWXXFXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4
• 重原子数：
  43
• 可旋转键数：
  15
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  311
• 氢给体数：
  7
• 氢受体数：
  17

文献信息

• Bag-1 peptide that inhibits prostate cancer
  申请人：Karlsruher Institut für Technologie

  公开号：EP2151452A1

  公开（公告）日：2010-02-10

  The present invention relates to a polypeptide having antitumor properties, to a vector encoding said polypeptide, to a host cell containing said vector, to uses of said polypeptide in the manufacture of a medicament for the treatment of cancer in patients, to a method comprising binding said polypeptide to molecular chaperones, and to a pharmaceutical composition containing said polypeptide.

  本发明涉及一种具有抗肿瘤特性的多肽、一种编码所述多肽的载体、一种含有所述载体的宿主细胞、所述多肽在制造治疗患者癌症的药物中的用途、一种包括将所述多肽与分子伴侣结合的方法以及一种含有所述多肽的药物组合物。
• USE OF TAUROLIDINE FOR TREATMENT OF LEUKEMIAS
  申请人：Oklahoma Medical Research Foundation

  公开号：EP0983069A1

  公开（公告）日：2000-03-08
• USE OF TAUROLIDINE FOR the manufacture of a medicament for the TREATMENT OF LEUKEMIAS
  申请人：Oklahoma Medical Research Foundation

  公开号：EP0983069B1

  公开（公告）日：2004-08-04
• CURCUMIN NANOPARTICLES AND METHODS OF PRODUCING THE SAME
  申请人：Kar, Santosh Kumar

  公开号：EP2349237A2

  公开（公告）日：2011-08-03
• BAG-1 PEPTIDE THAT INHIBITS PROSTATE CANCER
  申请人：Cato Andrew C. B.

  公开号：US20110190218A1

  公开（公告）日：2011-08-04

  The present invention relates to a polypeptide having antitumor properties, to a vector encoding said polypeptide, to a host cell containing said vector, to uses of said polypeptide in the manufacture of a medicament for the treatment of cancer in patients, to a method comprising binding said polypeptide to molecular chaperones, and to a pharmaceutical composition containing said polypeptide.