1,1'-(1,4-亚苯基)二脲 | 1205-90-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1,1'-(1,4-亚苯基)二脲
• 英文名称: 1,1'-(p-phenylene)bis(urea)
• 英文别名: 1,4-phenylenediurea；N,N''-p-phenylene-di-urea；N,N''-p-Phenylen-di-harnstoff；[4-(Carbamoylamino)phenyl]urea
• CAS: 1205-90-9
• 化学式: C₈H₁₀N₄O₂
• mdl: MFCD00570902
• 分子量: 194.193
• InChiKey: DPRNGQDPBFKLCK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  110
• 氢给体数：
  4
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,1'-(1,4-亚苯基)二脲 生成 N',N'''-dinitro-N,N''-(2,5-dinitro-p-phenylene)-di-urea
  参考文献：
  名称：

  DE907413

  摘要：

  公开号：
• 作为产物：
  描述：

  (4-cyanoamino-phenyl)-urea 在 盐酸 作用下， 生成 1,1'-(1,4-亚苯基)二脲
  参考文献：
  名称：

  Pierron, Annales de Chimie (Cachan, France), 1908, vol. <8>15, p. 185,207

  摘要：

  DOI：

文献信息

• Urea-Linked Covalent Organic Frameworks
  作者：Chenfei Zhao、Christian S. Diercks、Chenhui Zhu、Nikita Hanikel、Xiaokun Pei、Omar M. Yaghi

  DOI：10.1021/jacs.8b10612

  日期：2018.12.5

  2D covalent organic frameworks (COFs) with flexible urea linkages have been synthesized by condensation of 1,3,5-triformylphloroglucinol (TFP) with 1,4-phenylenediurea (BDU) or 1,1'-(3,3'-dimethyl-[1,1'-biphenyl]-4,4'-diyl)diurea (DMBDU). The resulting COF-117 and COF-118 undergo reversible structural dynamics within their layers, in response to inclusion and removal of guest molecules, emanating from

  通过 1,3,5-三甲酰基间苯三酚 (TFP) 与 1,4-苯二脲 (BDU) 或 1,1'-(3,3'-二甲基- [1,1'-联苯]-4,4'-二基）二脲（DMBDU）。所得的 COF-117 和 COF-118 在其层内经历可逆的结构动力学，以响应客体分子的包含和去除，源自尿素 CN 键旋转和层间氢键相互作用。这些化合物是第一个与尿素连接的 COF，有助于扩大网状化学的范围。
• PHENYL TETRAHYDROISOQUINOLINE COMPOUND SUBSTITUTED WITH HETEROARYL
  申请人：Taisho Pharmaceutical Co., Ltd.

  公开号：EP3173408A1

  公开（公告）日：2017-05-31

  The present invention provides a compound represented by the following formula [1] or a pharmaceutically acceptable salt thereof which has an excellent NHE3 inhibitory effect:         [Formula 15]     A-Y [1] wherein A represents a structure represented by the following formula [2]: wherein R11 and R12 each represent a halogen atom or the like, R2 represents C1-6 alkyl or the like, ring E represents triazole, tetrazole, pyrimidine, or the like, R31 and R32 each represent a hydrogen atom, C1-6 alkyl, C1-6 alkoxy, or the like, and W represents a single bond, the formula -NH-, the formula -O-, or the formula -CONH-, and Y represents a hydrogen atom or a structure represented by the following formula [3']:

  本发明提供了由下式[1]代表的化合物或其药学上可接受的盐，该化合物具有极佳的 NHE3 抑制作用： [式 15] A-Y [1］ 其中 A 代表下式[2]所代表的结构： 其中 R11 和 R12 分别代表卤素原子或类似物、 R2 代表 C1-6 烷基或类似物、 环 E 代表三唑、四唑、嘧啶或类似物、 R31 和 R32 各自代表氢原子、C1-6 烷基、C1-6 烷氧基或类似物，以及 W 代表单键、式-NH-、式-O-或式-CONH-，以及 Y 代表氢原子或下式[3']所代表的结构：
• Radiation curable inks containing curable gelator additives
  申请人：Breton P. Marcel

  公开号：US20060159850A1

  公开（公告）日：2006-07-20

  An ink preferably used in piezoelectric ink jet devices includes an ink vehicle that includes at least one curable monomer, at least one polymerizable organic gelator, at least one initiator, at least one colorant and optionally at least one low molecular mass non-reactive organic gelator and/or at least one thermal solvent. The use of the curable gelator enables the ink to form a gel state having a viscosity of at least 10 2.5 cps at very low temperatures of about 30° C. to about 50° C. The ink may thus be jetted at low temperatures of about 50° C. to about 90° C. The ink is heated to a first temperature above the gel point of the ink, jetted onto a surface maintained at a second temperature at which the ink forms a gel state, and when on the image receiving substrate, is exposed to radiation energy to polymerize the polymerizable components of the ink.

  压电喷墨装置中使用的墨水最好包括一种墨水载体，该载体包括至少一种可固化单体、至少一种可聚合有机凝胶剂、至少一种引发剂、至少一种着色剂和可选的至少一种低分子质量非反应性有机凝胶剂和/或至少一种热溶剂。使用可固化凝胶剂可使油墨形成凝胶状态，其粘度至少为 10 2.5 油墨被加热到高于油墨凝胶点的第一温度，喷射到保持在油墨形成凝胶态的第二温度的表面上，当喷射到图像接收基底上时，暴露在辐射能下，使油墨中的可聚合成分聚合。
• Selective and facile oxidative desulfurization of thioureas and thiobarbituric acids with singlet molecular oxygen generated from <i>trans-</i>3,5-dihydroperoxy-3,5-dimethyl-1,2-dioxolane
  作者：Davood Azarifar、Maryam Golbaghi

  DOI：10.1080/17415993.2015.1082181

  日期：2016.1.2

  An efficient and facile procedure using trans-3,5-dihydroperoxy-3,5-dimethyl-1,2-dioxolane has been developed for oxidative desulfurization of thioureas and thiobarbituric acids. The reactions proceeded smoothly very fast under mild conditions in basic media at room temperature to afford the respective ureas in excellent yields. Simple procedure and work up, mild conditions, high yields, short reaction times, use of highly potent and non-toxic oxidant are the main merits of the present method.[GRAPHICS].
• Tuned multifunctional linker molecules for electronic charge transport through organic-inorganic composite structures and use thereof
  申请人：Sony Deutschland GmbH

  公开号：EP1215205B1

  公开（公告）日：2007-11-21