1,1,3-三甲基-3-苯基丁胺 | 61455-15-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1,1,3-三甲基-3-苯基丁胺
• 英文名称: 1,1,3-trimethyl-3-phenylbutylamine
• 英文别名: 3-Phenyl-1.1.3-trimethylbutylamin；2,4-Dimethyl-4-phenylpentan-2-amine
• CAS: 61455-15-0
• 化学式: C₁₃H₂₁N
• 分子量: 191.316
• InChiKey: DEUVNZSGVYBCGE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1,1,3-三甲基-3-苯基丁胺 在 磺酰氯 作用下， 以 正己烷 为溶剂， 生成 N,N'-bis(1,1,3-trimethyl-3-phenylbutyl)sulfamide
  参考文献：
  名称：

  Prochazka,M., Collection of Czechoslovak Chemical Communications, 1976, vol. 41, p. 1557 - 1564

  摘要：

  DOI：
• 作为产物：
  描述：

  N-(1,1,3-trimethyl-3-phenylbutyl)formamide 在 sodium hydroxide 作用下， 生成 1,1,3-三甲基-3-苯基丁胺
  参考文献：
  名称：

  Prochazka,M., Collection of Czechoslovak Chemical Communications, 1976, vol. 41, p. 1557 - 1564

  摘要：

  DOI：

文献信息

• COMPOUND CONTAINING DIPHENYLMETHANE STRUCTURE AND USE THEREOF
  申请人：Guangzhou Trojan Pharmatec Ltd.

  公开号：EP3901132A1

  公开（公告）日：2021-10-27

  Disclosed are a compound containing a diphenylmethane structure and a use thereof, belonging to the technical field of compound and polypeptide synthesis. The structure of the compound containing a diphenylmethane structure of the present invention is represented by General Formula (1). The compound containing a diphenylmethane structure of the present invention contains a hydroxyl group, an amino group, a substituted amino group, and an active group, and can be used as an amino acid or peptide C-terminal protection reagent. A peptide synthesis reaction using this protection carrier has a fast reaction speed and a high reagent utilization rate in a suitable solvent system; post-treatment is carried out by means of simple liquid-liquid extraction separation, i.e. effective purification can be carried out, and finally, a product with a high purity can be obtained; and during a synthesis process, the change in solubility is small and an operation process has a strong universality, and therefore, the present method can be developed into a universal production method.

  本发明公开了一种含有二苯基甲烷结构的化合物及其用途，属于化合物和多肽合成技术领域。本发明含有二苯基甲烷结构的化合物的结构由通式（1）表示。本发明的含二苯基甲烷结构的化合物含有羟基、氨基、取代氨基和活性基团，可用作氨基酸或肽的 C-末端保护试剂。使用该保护载体进行多肽合成反应，在合适的溶剂体系中，反应速度快，试剂利用率高；通过简单的液液萃取分离进行后处理，即可以进行有效的纯化，最终可以得到纯度较高的产品；并且在合成过程中，溶解度变化小，操作过程具有较强的通用性，因此，本发明方法可以发展成为一种通用的生产方法。
• Oxygen-free direct conversion of methane and catalysts therefor
  申请人：DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES

  公开号：US10702854B2

  公开（公告）日：2020-07-07

  A process of methane catalytic conversion produces olefins, aromatics, and hydrogen under oxygen-free, continuous flowing conditions. Such a process has little coke deposition and realizes atom-economic conversion. Under the conditions encountered in a fixed bed reactor (i.e. reaction temperature: 750-1200° C.; reaction pressure: atmospheric pressure; the weight hourly space velocity of feed gas: 1000-30000 ml/g/h; and fixed bed), conversion of methane is 8-50%. The selectivity of olefins is 30-90%. And selectivity of aromatics is 10-70%. The catalyst for this methane conversion has a SiO2-based matrix having active species that are formed by confining dopant metal atoms in the lattice of the matrix.

  甲烷催化转化工艺可在无氧、连续流动的条件下生产烯烃、芳烃和氢气。这种工艺几乎没有焦炭沉积，可实现原子经济转换。在固定床反应器的条件下（即反应温度：750-1200 摄氏度；反应压力：常压；原料气重量小时空间速度：1000-30000 毫升/克/小时；固定床），甲烷的转化率为 8-50%。烯烃的选择性为 30-90%。芳烃的选择性为 10-70%。这种甲烷转化催化剂以二氧化硅为基质，其活性物质是通过在基质晶格中限制掺杂金属原子而形成的。
• Single-stranded nucleic acid molecule having delivery function and gene expression regulating ability
  申请人：BONAC CORPORATION

  公开号：US11142769B2

  公开（公告）日：2021-10-12

  The present invention provides a single-stranded nucleic acid molecule having a delivery function and capable of inhibiting expression of a target gene. The single-stranded nucleic acid molecule of the present invention is a single-stranded nucleic acid molecule composed of a region (Xc), a linker region (Lx) and a region (X), wherein said region (Xc) is complementary to said region (X), at least one of said region (X) and said region (Xc) contains an expression inhibitory sequence that inhibits expression of the target gene, and a bio-related substance having a delivery function is bonded to at least one selected from the group consisting of the 5′-terminus, the 3′-terminus, and said linker region (Lx).

  本发明提供了一种具有递送功能并能抑制靶基因表达的单链核酸分子。本发明的单链核酸分子是由区域（Xc）、连接区（Lx）和区域（X）组成的单链核酸分子，其中所述区域（Xc）与所述区域（X）互补、所述区域(X)和所述区域(Xc)中至少有一个包含表达抑制序列，可抑制目的基因的表达，具有递送功能的生物相关物质与至少一种选自5′-末端、3′-末端和所述连接区(Lx)的物质结合。
• Prochazka,M., Collection of Czechoslovak Chemical Communications, 1976, vol. 41, p. 1557 - 1564
  作者：Prochazka,M.

  DOI：——

  日期：——
• TIMBERLAKE J. W.; ALENDER J.; GARNER A. W.; HODGES M. L.; OZMERAL C.; SZI+, J. ORG. CHEM., 1981, 46, NO 10, 2082-2089
  作者：TIMBERLAKE J. W.、 ALENDER J.、 GARNER A. W.、 HODGES M. L.、 OZMERAL C.、 SZI+

  DOI：——

  日期：——