2-[2-(1H-benzimidazol-2-yl)phenyl]-3H-benzimidazol-5-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 2-[2-(1H-benzimidazol-2-yl)phenyl]-3H-benzimidazol-5-amine
• 化学式: C₂₀H₁₅N₅
• 分子量: 325.4
• InChiKey: WAMPXQLOMPYMBT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  25
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  83.4
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• BIS-BENZIMIDAZOLES AND RELATED COMPOUNDS AS POTASSIUM CHANNEL MODULATORS
  申请人：Icagen, Inc.

  公开号：EP1511744A2

  公开（公告）日：2005-03-09
• Bis-benzimidazoles and related compounds as potassium channel modulators
  申请人：ICAgen, Inc.

  公开号：US20040029925A1

  公开（公告）日：2004-02-12

  The present invention provides a genus of bis-benzimidazole compounds, methods and pharmaceutical compositions that are useful as modulators of potassium ion channels. The compounds of the invention are of use in both therapeutic and diagnostic methods.
• US7132439B2
  申请人：——

  公开号：US7132439B2

  公开（公告）日：2006-11-07
• US7482373B2
  申请人：——

  公开号：US7482373B2

  公开（公告）日：2009-01-27
• [EN] BIS-BENZIMIDAZOLES AND RELATED COMPOUNDS AS POTASSIUM CHANNEL MODULATORS<br/>[FR] BIS-BENZIMIDAZOLES ET COMPOSES ASSOCIES UTILISES COMME MODULATEURS DES CANAUX POTASSIQUES
  申请人：ICAGEN INC

  公开号：WO2003094861A2

  公开（公告）日：2003-11-20

  The present invention provides a genus of bis-benzimidazole compounds, methods and pharmaceutical compositions that are useful as modulators of potassium ion channels. The compounds of the invention are of use in both therapeutic and diagnostic methods.