1,2,3,5-四氯-4-甲基苯 | 875-40-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1,2,3,5-四氯-4-甲基苯
• 英文名称: 2,3,4,6-tetrachloro-toluene
• 英文别名: 2,3,4,6-Tetrachlor-toluol；1,2,3,5-tetrachloro-4-methyl-benzene；2.3.4.6-Tetrachlor-toluol；1,2,3,5-Tetrachloro-4-methylbenzene
• CAS: 875-40-1
• 化学式: C₇H₄Cl₄
• 分子量: 229.921
• InChiKey: UURGNCIPRITNBJ-UHFFFAOYSA-N

物化性质

• 熔点：
  94°C
• 沸点：
  253.97°C (estimate)
• 密度：
  1.5044 (estimate)
• 溶解度：
  氯仿（少量溶解）、二氯甲烷（少量溶解）、甲醇（少量，超声处理）

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,2,3,5-四氯-4-甲基苯 生成 2,3,4,6-tetrachloro-1-(trichloromethyl)benzene
  参考文献：
  名称：

  Beilstein; Kuhlberg, Justus Liebigs Annalen der Chemie, 1869, vol. 150, p. 294

  摘要：

  DOI：
• 作为产物：
  描述：

  2,3,4-三氯甲苯 在 氢化铝 、 汞 作用下， 生成 1,2,3,5-四氯-4-甲基苯
  参考文献：
  名称：

  Cohen; Dakin, Journal of the Chemical Society, 1904, vol. 85, p. 1280

  摘要：

  DOI：

文献信息

• POLYAZAMACROCYCLIC COMPOUND, AND A PRODUCTION METHOD AND A BIOMEDICAL USE THEREFOR
  申请人：Yoo Jeongsoo

  公开号：US20130004423A1

  公开（公告）日：2013-01-03

  According to the present invention, a novel polyazamacrocyclic compound which is used as a bifunctional chelating agent (BFC) can be synthesized selectively and in high yield. The novel polyazamacrocyclic compound synthesized by this method chelates with metals and thus can be conjugated with bioactive molecules such as peptides, and can be used in the diagnosis and treatment of medical conditions.

  根据本发明，一种新型聚氮大环化合物可选择性地且高收率地合成，用作双功能螯合剂（BFC）。通过这种方法合成的新型聚氮大环化合物与金属螯合，因此可以与生物活性分子如肽结合，并可用于医学疾病的诊断和治疗。
• Silsesquioxane derivative having functional group
  申请人：Ito Kenya

  公开号：US20060089504A1

  公开（公告）日：2006-04-27

  A conventional silsesquioxane derivative has the problems that the functional groups are restricted and the chemical structure is not readily controlled and that it is expensive. The present inventors have developed a process for producing a silsesquioxane derivative at a high yield by a simple process in order to solve such problems. The novel silsesquioxane derivative according to the present invention is controlled in a structure thereof and has a functional group, which is excellent in reactivity with a target compound, to be modified. The present invention relates to a production process for a silsesquioxane derivative represented by Formula (2), characterized by using a silicon compound represented by Formula (1). In Formula (1) and Formula (2), R is a group selected from hydrogen, alkyl, aryl and arylalkyl; M is a monovalent alkaline metal atom; at least one of Y is a group represented by Formula (3), and the remainder of Y is hydrogen; R 1 and R 2 in Formula (3) represent the same group as defined for R; and Z is a functional group or a group having a functional group.

  一种传统的六硅氧烷衍生物存在以下问题：功能基团受限、化学结构不易控制且价格昂贵。本发明人已经开发出一种通过简单工艺高产率生产六硅氧烷衍生物的方法，以解决这些问题。根据本发明的新型六硅氧烷衍生物在结构上受控，并具有与目标化合物反应活性优异的功能基团，可进行改性。本发明涉及一种生产六硅氧烷衍生物的方法，其特征在于使用化学式（1）所代表的硅化合物。在化学式（1）和化学式（2）中，R是从氢、烷基、芳基和芳基烷基中选择的基团；M是一价碱金属原子；至少一个Y是由化学式（3）表示的基团，其余的Y为氢；化学式（3）中的R1和R2代表与R定义相同的基团；Z是功能基团或具有功能基团的基团。
• Silsesquioxane derivative and process for producing the same
  申请人：Yoshida Kazuhiro

  公开号：US20060052623A1

  公开（公告）日：2006-03-09

  The PSQ silsesquioxane derivative of the invention is represented by Formula (1), and it may be utilized as additives to ordinary organic polymers for improving the flame retardancy, heat resistance, weather resistance, light resistance, electric insulating property, surface property, hardness, mechanical strength and chemical resistance thereof. In Formula (1), R is hydrogen, alkyl, aryl or arylalkyl; at least one Y is a group represented by Formula (2) and the other Y is hydrogen; in Formula (2), R 1 and R 2 are a group independently defined similarly to R; and Z is preferably a functional group, or a group having a functional group.

  该发明的PSQ硅氧烷衍生物由化学式（1）表示，可用作普通有机聚合物的添加剂，以改善其阻燃性、耐热性、耐候性、耐光性、电绝缘性、表面性能、硬度、机械强度和化学稳定性。在化学式（1）中，R为氢、烷基、芳基或芳基烷基；至少一个Y是由化学式（2）表示的基团，另一个Y为氢；在化学式（2）中，R1和R2是独立定义的与R类似的基团；Z最好是一个功能基团，或具有功能基团的基团。
• POLYSILOXANE COMPOUND AND METHOD OF PRODUCING THE SAME
  申请人：Ootake Nobumasa

  公开号：US20110178313A1

  公开（公告）日：2011-07-21

  A polysiloxane represented by the formula (1) or (2): where R, R 1 , R 2 , m and n are defined in the specification.

  由公式（1）或（2）表示的聚硅氧烷：其中R、R1、R2、m和n在规范中定义。
• Silsesquioxane derivative
  申请人：Morimoto Yoshitaka

  公开号：US20050215807A1

  公开（公告）日：2005-09-29

  If chlorosilane is used in order to introduce a functional group into a silsesquioxane derivative having Si—OH, by-produced hydrogen chloride has to be treated. However, if alkoxysilane is substituted for chlorosilane, the long reaction time is required. A production process for a silsesquioxane derivative represented by Formula (2) characterized by using a compound represented by Formula (1), has been developed in order to solve such problems of conventional techniques.

  如果氯硅烷用于将官能团引入具有Si—OH的硅氧烷衍生物中，副产的氢氯酸必须进行处理。然而，如果用烷氧基硅烷替代氯硅烷，则需要较长的反应时间。为了解决传统技术的这些问题，已经开发出一种以式(1)代表的化合物为特征的式(2)所表示的硅氧烷衍生物的生产过程。