1,2-二月桂酰-甘油-3-磷酰胆碱 | 63644-55-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 中文名称: 1,2-二月桂酰-甘油-3-磷酰胆碱
• 英文名称: dilauroylphosphatidylglycerol
• 英文别名: DLPG；Didodecanoyl-phosphatidylglycerol；1,2-Didodecanoyl-sn-glycero-3-phosphoryl-1'-sn-glycerin；dilauryloylphosphatidylglycerol；[3-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-2-dodecanoyloxypropyl] dodecanoate
• CAS: 63644-55-3
• 化学式: C₃₀H₅₉O₁₀P
• 分子量: 610.766
• InChiKey: LHCZDUCPSRJDJT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  41
• 可旋转键数：
  32
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  149
• 氢给体数：
  3
• 氢受体数：
  10

安全信息

• 海关编码：
  2931900090

文献信息

• Formulated and/or Co-Formulated Liposome Compositions Containing IDO Antagonist Prodrugs Useful In The Treatment of Cancer and Methods Thereof
  申请人：Nammi Therapeutics, Inc.

  公开号：US20210163418A1

  公开（公告）日：2021-06-03

  Formulated and/or co-formulated liposomes comprising IDO prodrugs and methods of making the liposomes are disclosed herein. The IDO prodrug compositions comprise a drug moiety, a lipid moiety, and linkage unit that inhibit IDO-1. The IDO prodrugs can be formulated and/or co-formulated into a liposome to provide a method of treating cancer, immunological disorders, and other disease by utilizing a targeted drug delivery vehicle.