1,2-二氢-1,2-蒽二醇 | 577-94-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 中文名称: 1,2-二氢-1,2-蒽二醇
• 英文名称: cis-1,2-dihydroxy-1,2-dihydroanthracene
• 英文别名: cis-1,2-dihydroanthracene-1,2-diol；1,2-Dihydro-1,2-anthracenediol；1,2-dihydroanthracene-1,2-diol
• CAS: 577-94-6
• 化学式: C₁₄H₁₂O₂
• 分子量: 212.248
• InChiKey: UJETWGFPSGKAAS-UHFFFAOYSA-N

物化性质

• 沸点：
  435.0±45.0 °C(Predicted)
• 密度：
  1.346±0.06 g/cm3(Predicted)
• 熔点：
  197 °C

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  9,10-二氢蒽 在 葡萄糖 、 维生素B1 E_. coli (pHA₁₇₁) 、 isoropyl β-D-thiogalactopyranoside 、 氨苄西林 作用下， 以 various solvent(s) 为溶剂， 以15 mg的产率得到1,2-二氢-1,2-蒽二醇
  参考文献：
  名称：

  各种三环稠合芳族化合物的氧化反应，利用大肠杆菌和带有几个芳烃双加氧酶基因的淡紫色链霉菌转化子进行。

  摘要：

  使用表达几种芳烃双加氧酶基因的大肠杆菌转化子的细胞，对包括各种三环稠合芳族化合物（例如芴，二苯并呋喃，二苯并噻吩，咔唑，a啶和菲啶）在内的芳烃（芳族化合物）进行了生物转化（生物转化）实验。带有从海洋细菌Nocardioides sp。衍生的菲双加氧酶（phdABCD）基因的大肠杆菌。菌株KP7转化了所有这些三环芳族化合物，而带有恶臭假单胞菌F1甲苯双加氧酶（todC1C2BA）基因或假拟疟原虫KF707联苯双加氧酶（bphA1A2A3A4）基因的大肠杆菌无法转化这些底物。出乎意料的是，大肠杆菌携带杂种双加氧酶（todC1 ::: 在甲苯和联苯双加氧酶之间具有亚基取代的bphA2A3A4）基因能够转化芴，二苯并呋喃和二苯并噻吩。还评估了携带菲双加氧酶基因的淡紫色链霉菌转化体的细胞对各种三环稠合芳族化合物的生物转化。该放线菌转化的能力与携带相应基因的大肠杆菌相似。用这些重组细菌细胞从芳香族化合

  DOI：

  10.1271/bbb.65.2472

文献信息

• [EN] AN INTEGRATED PROCESS TO COPRODUCE AROMATIC HYDROCARBONS AND ETHYLENE AND PROPYLENE<br/>[FR] PROCÉDÉ INTÉGRÉ POUR CO-PRODUIRE DES HYDROCARBURES AROMATIQUES ET DE L'ÉTHYLÈNE ET DU PROPYLÈNE
  申请人：SHELL OIL CO

  公开号：WO2010042440A1

  公开（公告）日：2010-04-15

  An integrated process for producing aromatic hydrocarbons and ethylene and/or propylene and optionally other lower olefins from low molecular weight hydrocarbons, preferably methane, which comprises: (a) contacting at least one low molecular weight alkane, preferably methane, with a halogen, preferably bromine. under process conditions sufficient to produce a monohaloalkane, preferably monobromomethane, (b) reacting the monohaloalkane in the presence of a coupling catalyst to produce aromatic hydrocarbons and C2+ alkanes, (c) separating the aromatic hydrocarbons from the product mixture of step (b) to produce aromatic hydrocarbons, and (d) cracking at least part of the C2+ alkanes in an alkane cracking system to produce ethylene and/or propylene and optionally other lower olefins.

  一种从低分子量碳氢化合物，优选为甲烷，生产芳香烃和乙烯和/或丙烯以及可选的其他较低烯烃的集成工艺，包括：(a) 在足以产生单卤代烷烃，优选为单溴甲烷的过程条件下，使至少一种低分子量烷烃，优选为甲烷，与卤素，优选为溴素接触；(b) 在偶联催化剂存在下将单卤代烷烃反应以产生芳香烃和C2+烷烃；(c) 将步骤(b)的产物混合物中的芳香烃分离出来以产生芳香烃；以及(d) 在烷烃裂解系统中裂解至少部分C2+烷烃以产生乙烯和/或丙烯以及可选的其他较低烯烃。
• INTEGRATED PROCESS TO COPRODUCE AROMATIC HYDROCARBONS AND ETHYLENE AND PROPYLENE
  申请人：FONG Howard Lam Ho

  公开号：US20100234637A1

  公开（公告）日：2010-09-16

  An integrated process for producing aromatic hydrocarbons and ethylene and/or propylene and optionally other lower olefins from low molecular weight hydrocarbons, preferably methane, which comprises: (a) contacting one or more low molecular weight alkanes, preferably methane, with a halogen, preferably bromine, under process conditions sufficient to produce a monohaloalkane, preferably monobromomethane, (b) reacting a first portion of the monohaloalkane in the presence of a coupling catalyst under process conditions sufficient to produce aromatic hydrocarbons and C 2-5 alkanes, (c) separating the aromatic hydrocarbons from the product mixture of step (b) to produce aromatic hydrocarbons, (d) reacting a second portion of the monohaloalkane in the presence of a coupling catalyst under process conditions sufficient to produce ethylene and/or propylene.

  从低分子量烃，最好是甲烷，生产芳香烃、乙烯和/或丙烯以及可选的其他低碳烯烃的综合过程，包括：(a)将一个或多个低分子量烷烃，最好是甲烷，与卤素，最好是溴，在足以产生单卤代烷，最好是溴代甲烷的工艺条件下接触；(b)在存在偶联催化剂的情况下，反应第一部分单卤代烷，在足以产生芳香烃和C2-5烷烃的工艺条件下；(c)将芳香烃从步骤(b)的产物混合物中分离出来，以产生芳香烃；(d)在存在偶联催化剂的情况下，反应第二部分单卤代烷，在足以产生乙烯和/或丙烯的工艺条件下。
• PROCESS FOR THE CONVERSION OF ETHANE TO MIXED LOWER ALKANES TO AROMATIC HYDROCARBONS
  申请人：Lauritzen Ann Marie

  公开号：US20090156870A1

  公开（公告）日：2009-06-18

  A process for producing aromatic hydrocarbons which comprises a) contacting ethane or mixed lower alkanes with an aromatic hydrocarbon conversion catalyst to produce reaction products including benzene, b) separating methane, hydrogen, and C 2-5 hydrocarbons from the reaction products of step a), and c) hydrodealkylating the remaining reaction products to produce benzene. In a preferred embodiment, the feed is split into two streams, one of which is catalytically or thermally cracked to produce ethylene which is then combined with the remaining ethane or lower alkanes and contacted with the aromatic hydrocarbon conversion catalyst.

  生产芳烃的过程包括a）将乙烷或混合低碳烷烃与芳烃转化催化剂接触，产生包括苯在内的反应产物，b）从步骤a）的反应产物中分离甲烷、氢气和C2-5烃烃，以及c）对剩余的反应产物进行脱烷基化处理以产生苯。在一种优选实施方式中，将原料分成两条流，其中一条流被催化或热裂解以产生乙烯，然后与剩余的乙烷或低碳烷烃结合，并与芳烃转化催化剂接触。
• Alteration of the Substrate Specificity of the Angular Dioxygenase Carbazole 1,9a-Dioxygenase
  作者：Hiromasa UCHIMURA、Tadafumi HORISAKI、Takashi UMEDA、Haruko NOGUCHI、Yusuke USAMI、Li LI、Tohru TERADA、Shugo NAKAMURA、Kentaro SHIMIZU、Tetsuo TAKEMURA、Hiroshi HABE、Kazuo FURIHATA、Toshio OMORI、Hisakazu YAMANE、Hideaki NOJIRI

  DOI：10.1271/bbb.80512

  日期：2008.12.23

  Carbazole 1,9a-dioxygenase (CARDO) consists of terminal oxygenase (CARDO-O) and electron transport components. CARDO can catalyze specific oxygenation for various substrates: angular dioxygenation for carbazole and dibenzo-p-dioxin, lateral dioxygenation for anthracene, and monooxygenation for methylene carbon of fluorene and sulfide sulfur of dibenzothiophene. To elucidate the molecular mechanism determining its unique substrate specificity, 17 CARDO-O site-directed mutants at amino acid residues I262, F275, Q282, and F329, which form the substrate-interacting wall around the iron active site by CARDO-O crystal structure, were generated and characterized. F329 replacement dramatically reduced oxygenation activity. However, several mutants produced different products from the wild-type enzyme to a large extent: I262V and Q282Y (1-hydroxycarbazole), F275W (4-hydroxyfluorene), F275A (unidentified cis-dihydrodiol of fluoranthene), and I262A and I262W (monohydroxydibenzothiophenes). These results suggest the possibility that the respective substrates bind to the active sites of CARDO-O mutants in a different orientation from that of the wild-type enzyme.

  Carbazole 1,9a-二氧化酶（CARDO）由末端氧化酶（CARDO-O）和电子传递组件组成。CARDO能够对多种底物催化特定的氧化反应：对喹啉和二苯并-对-二氧的角氧化，对蒽的侧氧化，以及对弗鲁安的亚甲基碳和二苯并噻吩的硫的单氧化。为了阐明决定其独特底物特异性的分子机制，生成并表征了17个CARDO-O的定点突变体，这些突变体位于氨基酸残基I262、F275、Q282和F329，这些残基通过CARDO-O的晶体结构形成围绕铁活性位点的底物相互作用壁。F329的替换显著降低了氧化活性。然而，几个突变体与野生型酶相比，产生了不同的产物：I262V和Q282Y（1-羟基喹啉），F275W（4-羟基弗鲁安），F275A（未鉴定的弗鲁安烯顺式二氢二醇），以及I262A和I262W（单羟基二苯并噻吩）。这些结果表明，不同底物可能以不同于野生型酶的取向结合在CARDO-O突变体的活性位点。
• Green Electroluminescent Compounds and Organic Electroluminescent Device Using the Same
  申请人：Hyun Seung-Hak

  公开号：US20090128010A1

  公开（公告）日：2009-05-21

  The present invention relates to organic electroluminescent compounds represented by Chemical Formula 1 or 2, a process for preparing the same, and an organic light emitting diode (OLED) which comprises, as a luminescent region interposed between an anode and a cathode, at least one compound (s) selected from those represented by Chemical Formula 1 or 2, and at least one compound selected from anthracene derivatives, benz[a]anthracene derivatives and naphthacene derivatives. The electroluminescent compound according to the present invention is a green electroluminescent compound having maximized electroluminescent efficiency and lifetime of device.

  本发明涉及有机电致发光化合物，其化学式为1或2，制备该化合物的方法以及包括至少一种化合物（s）和蒽衍生物、苯并[a]蒽衍生物和萘蒽衍生物中至少一种化合物作为发光区域的有机发光二极管（OLED），该OLED位于阳极和阴极之间。根据本发明的电致发光化合物是一种绿色电致发光化合物，具有最大化的电致发光效率和器件寿命。