1,3-二氢-1,3,3-三甲基-6'-(4-吗啉基)-螺[2H-吲哚-2,3'-[3H]萘并[2,1-b][1,4]恶嗪] | 114747-48-7

• 物质功能分类: 化学试剂 - 有机试剂 - 多环化合物
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶嗪类
• 中文名称: 1,3-二氢-1,3,3-三甲基-6'-(4-吗啉基)-螺[2H-吲哚-2,3'-[3H]萘并[2,1-b][1,4]恶嗪]
• 中文别名: 1,3-二氢-1,3,3-三甲基-6'-（4-吗啉基）-螺[2H-吲哚-2,3'-[3H]萘并[2,1-B][1,4]恶嗪]
• 英文名称: 1,3,3-trimethyl-6'-morpholinospiro(indoline-2,3'-3H-naphtho[2,1-b][1,4]-oxazine)
• 英文别名: 1,3,3-trimethyl-6-(4-morpholino)spiro{indolino-2,3'-[3H]naphtho[2,1-b]oxazine}；1,3,3-trimethyl-6'-morpholinospiro(indoline-2,3'-naphtho[2,1-b][1,4]oxazine)；1,3,3-trimethyl-6'-morpholinospiro(indolino-2,3'-[3H]naphth[2,1-b]oxazine)；6'-Morpholino-1,3,3-trimethylspiro(indoline-2,3'-[3H]naphth[2,1-b][1,4]oxazine)；1,3,3-Trimethyl-6'-morpholinospiro[indoline-2,3'-naphtho[2,1-b][1,4]oxazine]；1',3',3'-trimethyl-6-morpholin-4-ylspiro[benzo[f][1,4]benzoxazine-3,2'-indole]
• CAS: 114747-48-7
• 化学式: C₂₆H₂₇N₃O₂
• 分子量: 413.519
• InChiKey: VBGVMVBBKHCPIQ-UHFFFAOYSA-N

物化性质

• 熔点：
  196℃
• 沸点：
  652.7±55.0 °C(Predicted)
• 密度：
  1.26±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  31
• 可旋转键数：
  1
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  37.3
• 氢给体数：
  0
• 氢受体数：
  5

安全信息

• 危险性防范说明：
  P261,P305+P351+P338
• 危险性描述：
  H302,H315,H319,H335

反应信息

• 作为反应物：
  描述：

  1,3-二氢-1,3,3-三甲基-6'-(4-吗啉基)-螺[2H-吲哚-2,3'-[3H]萘并[2,1-b][1,4]恶嗪] 在 氢气 作用下， 生成
  参考文献：
  名称：

  Gabbutt, Christopher D.; Hepworth, John D.; Heron, B. Mark, Molecular Crystals and Liquid Crystals Science and Technology, Section A: Molecular Crystals and Liquid Crystals, 2000, vol. 345, p. 647/323 - 652/328

  摘要：

  DOI：
• 作为产物：
  描述：

  1-亚硝基-2-萘酚 以 甲醇 为溶剂， 生成 1,3-二氢-1,3,3-三甲基-6'-(4-吗啉基)-螺[2H-吲哚-2,3'-[3H]萘并[2,1-b][1,4]恶嗪]
  参考文献：
  名称：

  Red Colouring Photochromic 6′-Substituted Spiroindolinon Aphth[2,1-b][1,4]Oxazines

  摘要：

  Electron donating/withdrawing substituents and electronegative centres have been successfully employed in substantially widening the range of photo-generated colours available in the spiroindolinonaphthoxazine class of photochromic materials.

  DOI：

  10.1080/10587259408037780

文献信息

• One-Pot Synthesis of 6′-Amino-Substituted Spirooxazines
  作者：O. A. Fedorova、A. V. Koshkin、V. Lokshin、A. Samat、S. P. Gromov

  DOI：10.1055/s-2005-870006

  日期：——

  A one-pot synthesis of 6'-amino-substituted spiroindolinonaphth[2,1-b][1,4]oxazines is developed through the condensation of 2-methylene-1,3,3-trimethylindoline derivatives and 1-amino-2-naphthol in the presence of different secondary amines and oxidizing agents using methanol or toluene as the solvent. The main advantage of the method is its simplicity, and starting from readily accessible reagents

  通过 2-methylene-1,3,3-trimethylindoline 衍生物与 1-amino-2 的缩合，一锅法合成 6'-氨基取代的螺吲哚啉萘 [2,1-b][1,4] 恶嗪-萘酚在不同的仲胺和氧化剂的存在下使用甲醇或甲苯作为溶剂。该方法的主要优点是简单，并且从容易获得的试剂开始，它可以在温和的反应条件下以良好的收率制备螺萘恶嗪的氨基衍生物。
• One-Pot Synthesis of Photochromic 6′-Amino-Substituted Spirooxazines from 1-Nitroso-2-naphthol Zinc Chelate and Indoline Base
  作者：Mei-Li Pang、Ji-Ben Meng、Hui-Juan Zhang、Pei-Pei Liu、Zhi-Hong Zou、Jie Han

  DOI：10.1055/s-0030-1258197

  日期：2010.10

  A series of spirooxazine derivatives containing nitrogen heterocycles were synthesized through the condensation of 2-methylene-1,3,3-trimethylindoline derivatives with the zinc salt of 1-nitroso-2-naphthol using ethanol as solvent. The method is simple, starts from readily accessible and inexpensive reagents, and leads to the synthesis of 6′-substituted spirooxazines in moderate to good yields. We simplified the workup and found that, for some target compounds, recrystallization can effectively improve efficiency of the separation and purification.

  以乙醇为溶剂，通过 2-亚甲基-1,3,3-三甲基吲哚啉衍生物与 1-亚硝基-2-萘酚锌盐的缩合，合成了一系列含氮杂环的螺噁嗪衍生物。该方法简单易行，从容易获得且价格低廉的试剂开始，以中等至良好的收率合成 6′-取代的螺噁嗪。我们简化了操作步骤，并发现对于某些目标化合物，重结晶可以有效提高分离和纯化的效率。
• Transformation of 6′-aminosubstituted spironaphthoxazines induced by Pb(II) and Eu(III) cations
  作者：Olga A. Fedorova、Alexander V. Koshkin、Sergey P. Gromov、Yuri P. Strokach、Tatjana M. Valova、Michael V. Alfimov、Alexei V. Feofanov、Iouri S. Alaverdian、Vladimir A. Lokshin、Andre Samat

  DOI：10.1002/poc.890

  日期：2005.6

  The transformation of spiroindolinonaphth[2,1-b][1,4]oxazines (SNOs) conjugated with aza-15(18)-crown-5(6) ether moieties or morpholine in the presence of Pb2+ or lanthanoid cations in MeCN solution was studied by UV–Vis, NMR and surface-enhanced resonance Raman scattering spectroscopy methods. The Pb2+ or Eu3+ cations induce the formation of the betaine merocyanine form of SNO. When the merocyanine

  在Pb 2+或镧系元素阳离子存在下，与aza-15（18）-crown-5（6）醚部分或吗啉共轭的螺吲哚并萘并[2,1- b ] [1,4]恶嗪（SNOs）的转化通过UV-Vis，NMR和表面增强共振拉曼散射光谱法研究了MeCN溶液。Pb 2+或Eu 3+阳离子诱导甜菜碱亚花青形式的SNO形成。当将花菁复合物置于黑暗中时，不可逆地和区域选择性地形成相应的恶唑衍生物。版权所有©2005 John Wiley＆Sons，Ltd.
• Photochromic articles
  申请人：PILKINGTON PLC

  公开号：EP0245020A2

  公开（公告）日：1987-11-11

  A plastic organic photochromic article, typically a lens such as an ophthalmic lens or a window such as a vehicle roof light, comprising a plastics host material having a photochromic compound incorporated therein or applied thereto, the article being characterised in that it exhibits the following properties, measured at Air Mass 2 at 25 °C: (a) an integrated visible transmission in the faded state (B.IVT) ranging from 90 to 25 %, (b) an integrated visible transmission in the darkened state (D.IVT) ranging from 1 to 50 %, preferably 4 to 30 %, (c) the rate of darkening of the article when it is exposed to actinic radiation is such that 88% of the darkening range is achieved in 30 seconds or less, i.e.TB8 30 secs, (d) the rate of fading of the article from its fully darkened condition is such that more than 60 % of the optical density range is recovered in 60 seconds, i.e. % ODG-1 60%, and (e) the induced optical density of the article, i.e. the change in the optical density of the article, in moving from the faded state (B.IVT) to the darkened state (D.IVT), is greater than 0.45. Typically, the photochromic compound is a spiro-oxazine compound of general formula (II),

  一种塑料有机光致变色制品，通常是镜片（如眼科镜片）或车窗（如车顶灯），由塑料主材料组成，塑料主材料中含有或涂有光致变色化合物： (a) 在褪色状态下的综合可见光透射率（B.IVT）从 90%到 25%不等、 (b) 变暗状态下的综合可见透射率（D.IVT）为 1-50%，最好为 4-30%、 (c) 当物品暴露在光辐射下时，其变黑的速度能在 30 秒或更短时间内达到变黑范围的 88%，即 TB8 30 秒、 (d) 物品从完全变暗状态开始褪色的速度为 60 秒内恢复 60%以上的光密度范 围，即 % ODG-1 60%，以及 (e) 物品的诱导光密度，即物品从褪色状态（B.IVT）到变暗状态（D.IVT）的光密度变化大于 0.45。 典型的光致变色化合物是通式（II）的螺嗪化合物、
• PHOTOCHROMIC POLYPROPYLENE FIBER AND PREPARATION METHOD THEREOF
  申请人：Taiwan Textile Research Institute

  公开号：EP3901205A1

  公开（公告）日：2021-10-27

  A photochromic polypropylene fiber is provided. The photochromic polypropylene fiber includes about 98 to 99 parts by weight of polypropylene, about 0.2 to 0.8 parts by weight of a photochromic agent, about 0.1 to 1 parts by weight of an ultraviolet absorber, and about 0.1 to 1 parts by weight of a light stabilizer. The ultraviolet absorber includes and the light stabilizer includes wherein n is 10-14. A preparation method of the photochromic polypropylene fiber is further provided.

  提供一种光致变色聚丙烯纤维。光致变色聚丙烯纤维包括约 98 至 99 重量份的聚丙烯、约 0.2 至 0.8 重量份的光致变色剂、约 0.1 至 1 重量份的紫外线吸收剂和约 0.1 至 1 重量份的光稳定剂。紫外线吸收剂包括 光稳定剂包括 其中 n 为 10-14。还提供了一种光致变色聚丙烯纤维的制备方法。