1,3-二溴庚烷 | 42474-22-6

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机溴化物
• 中文名称: 1,3-二溴庚烷
• 英文名称: 1,3-Dibrom-heptan
• 英文别名: 1,3-dibromo-heptane；1,3-Dibromoheptane；1,3-dibromoheptane
• CAS: 42474-22-6
• 化学式: C₇H₁₄Br₂
• 分子量: 257.996
• InChiKey: YSHNCQWGGQDYBI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,3-二溴庚烷 在 乙醇 、 锌 作用下， 生成 丁基环丙烷
  参考文献：
  名称：

  CYCLOPROPANE HYDROCARBONS FROM gamma-BROMOETHERS¹

  摘要：

  DOI：

  10.1021/jo01121a001
• 作为产物：
  描述：

  丁基环丙烷 在 N-溴代丁二酰亚胺(NBS) 、 溴 作用下， 以 二氯甲烷 为溶剂， 生成 1,3-二溴庚烷
  参考文献：
  名称：

  Reactions of alkylcyclopropanes with bromine and with hydrogen bromide

  摘要：

  DOI：

  10.1021/ja00421a024

文献信息

• COMPOSITIONS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS
  申请人：Mahmood Ashfaq

  公开号：US20120269724A1

  公开（公告）日：2012-10-25

  The present invention relates to compounds and related technetium and rhenium complexes thereof which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled metal complexes, particularly tissues, organs, or tumors which express certain receptors to which the compounds or complexes of the invention have an affinity. The present invention also relates to methods of treating cancer, particularly those cancer lines which express certain receptors to which the compounds or complexes of the invention have an affinity. In yet another embodiment, the present invention provides methods of imaging and/or inhibiting receptors or neuroreceptors using compounds or complexes of the invention which have an affinity for the receptor or neuroreceptor to be imaged and/or inhibited.

  本发明涉及化合物及其相关的锝和铼配合物，适用于组织、器官或肿瘤的成像或治疗。在另一实施例中，本发明涉及使用放射标记的金属配合物成像组织、器官或肿瘤的方法，特别是那些表达本发明化合物或配合物具有亲和力的特定受体的组织、器官或肿瘤。本发明还涉及治疗癌症的方法，特别是那些表达本发明化合物或配合物具有亲和力的特定受体的癌细胞系。在另一实施例中，本发明提供了使用具有与待成像和/或抑制的受体或神经受体具有亲和力的本发明化合物或配合物成像和/或抑制受体或神经受体的方法。
• POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP
  申请人：BRIDGESTONE CORPORATION

  公开号：US20160289355A1

  公开（公告）日：2016-10-06

  A method for preparing a functionalized polymer, the method comprising the steps of (i) preparing a halocarbon-activated nitrogen heterocycle containing a functional group, (ii) preparing a reactive polymer, and (iii) reacting the reactive polymer with the halocarbon-activated nitrogen heterocycle containing a functional group.
• US8747810B2
  申请人：——

  公开号：US8747810B2

  公开（公告）日：2014-06-10
• US9738738B2
  申请人：——

  公开号：US9738738B2

  公开（公告）日：2017-08-22
• [EN] COMPOSITIONS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS<br/>[FR] COMPOSITIONS ET PROCÉDÉS D'IMAGERIE DE TISSUS, ORGANES ET TUMEURS
  申请人：HARVARD COLLEGE

  公开号：WO2010144891A1

  公开（公告）日：2010-12-16

  The present invention relates to compounds and related technetium and rhenium complexes thereof which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled metal complexes, particularly tissues, organs, or tumors which express certain receptors to which the compounds or complexes of the invention have an affinity. The present invention also relates to methods of treating cancer, particularly those cancer lines which express certain receptors to which the compounds or complexes of the invention have an affinity. In yet another embodiment, the present invention provides methods of imaging and/or inhibiting receptors or neuroreceptors using compounds or complexes of the invention which have an affinity for the receptor or neuroreceptor to be imaged and/or inhibited.