1-(2,3-二甲基苯基)吡咯烷 | 957065-89-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 中文名称: 1-(2,3-二甲基苯基)吡咯烷
• 中文别名: 1-(2,3-二甲基苯基)吡咯
• 英文名称: 1-(2,3-Dimethylphenyl)pyrrolidine
• CAS: 957065-89-3
• 化学式: C₁₂H₁₇N
• mdl: MFCD09878389
• 分子量: 175.27
• InChiKey: OPHSFWFVNOENHP-UHFFFAOYSA-N

物化性质

• 沸点：
  293.5±29.0 °C(Predicted)
• 密度：
  0.992±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 危险品标志：
  Xi
• 海关编码：
  2933990090

文献信息

• Diverse carbene transferase enzyme catalysts derived from a P450 enzyme
  申请人：California Institute of Technology

  公开号：US11525123B2

  公开（公告）日：2022-12-13

  The present disclosure provides cytochrome P450 variants useful for carrying out in vivo and in vitro carbene insertion reactions. Methods for preparing carbene insertion products including cyclopropenes, cyclopropanes, bicyclobutanes, substituted lactones, cyclized compounds, and substituted amines are also described.

  本公开提供了有助于进行体内和体外碳烯插入反应的细胞色素 P450 变体。还描述了制备碳烯插入产物（包括环丙烯、环丙烷、双环丁烷、取代内酯、环化化合物和取代胺）的方法。
• DIVERSE CARBENE TRANSFERASE ENZYME CATALYSTS DERIVED FROM A P450 ENZYME
  申请人：California Institute of Technology

  公开号：US20210292718A1

  公开（公告）日：2021-09-23

  The present disclosure provides cytochrome P450 variants useful for carrying out in vivo and in vitro carbene insertion reactions. Methods for preparing carbene insertion products including cyclopropenes, cyclopropanes, bicyclobutanes, substituted lactones, cyclized compounds, and substituted amines are also described.