6-[2-[2-[7-(Diethylamino)-2,4-dioxochromen-3-ylidene]ethylidene]-5-[dihydroxy(oxo)-lambda6-sulfanylidene]-3,3-dimethylindol-1-ium-1-yl]hexanoic acid

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 6-[2-[2-[7-(Diethylamino)-2,4-dioxochromen-3-ylidene]ethylidene]-5-[dihydroxy(oxo)-lambda6-sulfanylidene]-3,3-dimethylindol-1-ium-1-yl]hexanoic acid
• 英文别名: 6-[2-[2-[7-(diethylamino)-2,4-dioxochromen-3-ylidene]ethylidene]-5-[dihydroxy(oxo)-λ6-sulfanylidene]-3,3-dimethylindol-1-ium-1-yl]hexanoic acid
• 化学式: C31H37N2O8S+
• 分子量: 597.7
• InChiKey: ACILOXWOYCJZEB-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  42
• 可旋转键数：
  12
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  153
• 氢给体数：
  3
• 氢受体数：
  9

文献信息

• COUMARIN-BASED CYANINE DYES FOR NON-SPECIFIC PROTEIN BINDING
  申请人：Berkelman Thomas R.

  公开号：US20100041163A1

  公开（公告）日：2010-02-18

  Protein dyes whose molecular structure is that of a coumarin moiety coupled to a quaternary ammonium heterocycle through a vinyl or polyvinyl linkage demonstrate the ability to associate with proteins in a non-covalent, non-specific manner at low pH, where the associated form displays a significantly higher fluorescence emission than the unassociated form. This makes the dyes useful as selective labels for proteins at the low pH and eliminates the need for the removal of extraneous components from the medium in which the proteins reside prior to detection.
• US7563907B2
  申请人：——

  公开号：US7563907B2

  公开（公告）日：2009-07-21
• US7625758B2
  申请人：——

  公开号：US7625758B2

  公开（公告）日：2009-12-01
• US7863048B2
  申请人：——

  公开号：US7863048B2

  公开（公告）日：2011-01-04