氟化羟基可力定

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 氟化羟基可力定
• 英文名称: 2,4,6-trimethylpyridine-bishydrofluoride
• 英文别名: 2,4,6-Trimethylpyridinium fluoride；2,4,6-trimethylpyridin-1-ium;fluoride
• 化学式: C₈H₁₁N*2FH
• mdl: MFCD00066483
• 分子量: 161.195
• InChiKey: IDKGEEJHKVNSCI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.53
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.375
• 拓扑面积：
  12.9
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  bis(cyclopentadienyl)dimethylzirconium(IV) 、 氟化羟基可力定 以 二氯甲烷 为溶剂， 以92%的产率得到bis(η5-cyclopentadienyl)zirconium(IV) difluoride
  参考文献：
  名称：

  2,4,6-Trimethylpyridine–bishydrofluoride: a novel fluorinating reagent for organo transition-metal alkyls

  摘要：

  Complexes [M(eta(5)-C(5)Me(5))F-3] (M = Zr 2, Hf 5), [Zr(eta(5)-C5H5)F-2] 7 and [Hf(eta(5)-C(5)Me(5))(2)F-2] 8 are obtained by treating the corresponding metal alkyls with [tmpy .(HF)(2)] (tmpy = 2,4,6-trimethylpyridine); using an excess of [tmpy .(HF)(2)] in the preparation of 2 and 5 leads to the complexes [Htmpy][{M(eta(5)-C(5)Me(5))F-2}(mu-F)(3)] (M = Zr 3, Hf 6), respectively and a crystal structure determination of 3 confirms its ionic nature; [Ti(eta(5)-C(5)Me(5))Cl2F] 10 and 2 were synthesised also from their corresponding alkyls by alkyl-fluorine exchange using Me(3)SnF.

  DOI：

  10.1039/cc9960000029
• 作为试剂：
  描述：

  1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene 在 氟化羟基可力定 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 以80%的产率得到
  参考文献：
  名称：

  Collidinium- und Imidazolium-Salze Fluor-haltiger Anionen. Die Kristallstruktur von [CollH]₂ [AsF₆][As₂ F₁₁] (Coll = 2,4,6-Trimethylpyridin) / Collidinium and Imidazolium Salts of Fluorine-Containing Anions. The Crystal Structure of [CollH]₂[AsF₆][As₂F₁₁] (Coll = 2,4,6-Trimethylpyridine)

  摘要：

  含氟阴离子的Collidinium和Imidazolium盐的晶体结构，[CollH]₂ [AsF₆][As₂F₁₁] (Coll = 2,4,6-三甲基吡啶)的晶体结构。通过s-Collidine (1,Coll)和n HF (n = 1-2)的水合物化合物形成，通过升华转化为[CollH]⁺ [HF₂]^- (2)。[CollH]₂[AsF₆][As₂F] J (3)可从1和超酸体系HF/AsF5中获得。2与2,3-二氢-1,3-二异丙基-4,5-二甲基咪唑-2-基亚胺（4,Im）反应，得到咪唑盐[ImH]⁺ [HF₂]^- (5)。讨论了[CollH]₂[AsF₆][As₂Fn ] (3)的晶体结构中的氢键。

  DOI：

  10.1515/znb-2001-0710

文献信息

• Hydrogen fluoride adduct of an ambiphilic phosphine–borane: NMR characterization and theoretical analysis of the bonding situation
  作者：Sylvie Moebs-Sanchez、Nathalie Saffon、Ghenwa Bouhadir、Laurent Maron、Didier Bourissou

  DOI：10.1039/c002068k

  日期：——

  The HF adduct of the ambiphilic phosphine–borane [o-iPr2P(C6H4)BMes2] has been spectroscopically characterized and the nature of the interaction between the ensuing hydrogenophosphonium and fluoroborate moieties has been analyzed computationally.

  两亲性膦硼烷 [o-iPr2P(C6H4)BMes2] 的 HF 加合物已进行了光谱表征，并通过计算分析了随后产生的氢膦和氟硼酸盐部分之间的相互作用的性质。
• In fluorine-containing media homogeneously dispersible nanoparticles and media containing the same
  申请人：Nanosolutions GmbH

  公开号：EP1431352A1

  公开（公告）日：2004-06-23

  The present invention relates to nanoparticles being dispersible in fluorine-containing media, comprising: an inorganic nanoparticle core, and an outer layer comprising an organic compound modifying the surface of the nanoparticle core and having a first portion comprising at least one linking group for the nanoparticle and a second portion comprising at least one fluorinated group, a process for their manufacture and fluorinated media containing the same.

  本发明涉及可在含氟介质中分散的纳米颗粒，包括 无机纳米粒子核，以及 由有机化合物组成的外层，该有机化合物对纳米粒子核心的表面进行了改性，其第一部分包含至少一个纳米粒子连接基团，第二部分包含至少一个氟化基团；本发明还涉及其制造工艺和含有本发明的含氟介质。
• Core/shell nanoparticles suitable for (F) RET-assays
  申请人：Nanosolutions GmbH

  公开号：EP1473347A1

  公开（公告）日：2004-11-03

  The present invention relates to luminescent inorganic nanoparticles comprising (a) a core made from a first metal salt or oxide being surrounded by (b) a shell made from a second metal salt or oxide being luminescent and having non-semiconductor properties. These particles can be advantageously used in (fluorescence) resonance energy transfer ((F)RET)-based bioassays in view of their higher (F)RET efficiency.

  本发明涉及发光无机纳米粒子，包括 (a) 由第一种金属盐或氧化物制成的核心，其周围环绕着 (b) 由第二种金属盐或氧化物制成的外壳，具有发光和非半导体特性。 鉴于这些颗粒具有较高的荧光共振能量转移（(F)RET）效率，因此可以很好地用于基于（荧光）共振能量转移（(F)RET）的生物测定。
• Luminescent core/shell nanoparticles
  申请人：Nanosolutions GmbH

  公开号：EP1473348A1

  公开（公告）日：2004-11-03

  The present invention relates to Luminescent nanoparticles comprising (a) a core made from a luminescent metal salt selected from phosphates, sulfates or fluorides, being surrounded by (b) a shell made from a metal salt or oxide capable of preventing or reducing energy transfer from the core after its electronic excitation to the surface of the nanoparticle, e.g. a shell made from a non-luminescent metal salt or oxide,    which are characterized by higher quantum yields and can be used in various fields including light generation and security marking.

  本发明涉及发光纳米粒子，包括 (a) 由选自磷酸盐、硫酸盐或氟化物的发光金属盐制成的内核，其周围有 (b) 由金属盐或氧化物制成的外壳，该外壳能够阻止或减少电子激发后能量从内核转移到纳米粒子表面，例如由非发光金属盐或氧化物制成的外壳、 其特点是量子产率较高，可用于包括光生成和安全标识在内的多个领域。
• Synthesis of nanoparticles
  申请人：——

  公开号：US20030032192A1

  公开（公告）日：2003-02-13

  The present invention relates to methods for the preparation of inorganic nanoparticles capable of fluorescence, wherein the nanoparticles consist of a host material that comprises at least one dopant. The synthesis of the invention in organic solvents allows to gain a considerably higher yield compared to the prior art synthesis in water. All kinds of objects can advantageously be marked and reliably authenticated by using an automated method on the basis of a characteristic emission. Further, the size distribution of the prepared nanoparticles is narrower which renders a subsequent size-selected separation process superfluous.

  本发明涉及制备具有荧光功能的无机纳米粒子的方法，其中纳米粒子由包含至少一种掺杂剂的主材料组成。本发明在有机溶剂中的合成比现有技术在水中的合成产量要高得多。利用自动方法，可以根据发射特征对各种物体进行标记和可靠的鉴定。此外，所制备的纳米颗粒的粒度分布更窄，这使得随后的粒度选择分离过程变得多余。