10,11-二氢-5-(3-哌啶丙酰基)-5H-二苯并[b,f]氮杂卓 | 26082-81-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯氮卓类
• 中文名称: 10,11-二氢-5-(3-哌啶丙酰基)-5H-二苯并[b,f]氮杂卓
• 英文名称: 10,11-Dihydro-5-(3-piperidinopropionyl)-5H-dibenz(b,f)azepine
• 英文别名: 1-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-3-piperidin-1-ylpropan-1-one
• CAS: 26082-81-5
• 化学式: C₂₂H₂₆N₂O
• 分子量: 334.5
• InChiKey: HZJCVBIFQOESNH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  25
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  23.6
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2933990090

文献信息

• TRICYCLIC COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF
  申请人：ORLOW Seth J.

  公开号：US20090304615A1

  公开（公告）日：2009-12-10

  A method of identification of tricyclic compounds (formula I) that control melanin synthesis (melanogenesis), and the use of such compounds and compositions thereof to modify (e.g., inhibit) melanin production are disclosed. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of conditions that are causally related to aberrant melanogenesis activity including by way of non-limiting example, hyperpigmentation and others.
• [EN] TRICYCLIC COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF<br/>[FR] COMPOSÉS TRICYCLIQUES EN TANT QUE MODIFICATEURS DE LA MÉLANOGENÈSE ET LEURS UTILISATIONS
  申请人：UNIV NEW YORK SCHOOL MEDICINE

  公开号：WO2009064493A1

  公开（公告）日：2009-05-22

  A method of identification of tricyclic compounds (formula I) that control melanin synthesis (melanogenesis), and the use of such compounds and compositions thereof to modify (e.g., inhibit) melanin production are disclosed. Formula (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of conditions that are causally related to aberrant melanogenesis activity including by way of non-limiting example, hyperpigmentation and others.