2,2-二甲基-4,4-联苯二醇 | 59517-19-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2,2-二甲基-4,4-联苯二醇
• 中文别名: 2,2'-二甲基-4,4'-联苯二醇
• 英文名称: 2,2'-dimethyl-4,4'-dihydroxy-1,1'-biphenyl
• 英文别名: 2,2'-dimethyl-4,4'-dihydroxybiphenol；2,2'-dimethyl-4,4'-dihydroxybiphenyl；2,2'-dimethyl-4,4'-biphenol；2,2'-Dimethyl-biphenyl-4,4'-diol；4.4'-Dioxy-2.2'-dimethyl-diphenyl；2,2'-Dimethyl-4,4'-dihydroxy-biphenyl；2,2'-Dimethyl-4,4'-biphenyldiol；4-(4-hydroxy-2-methylphenyl)-3-methylphenol
• CAS: 59517-19-0
• 化学式: C₁₄H₁₄O₂
• 分子量: 214.264
• InChiKey: GTFQLBWTUKSJQG-UHFFFAOYSA-N

物化性质

• 熔点：
  123 °C(Solv: benzene (71-43-2))
• 沸点：
  343.7±37.0 °C(Predicted)
• 密度：
  1.163±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,2-二甲基-4,4-联苯二醇 在 sodium hydroxide 、 N-溴代丁二酰亚胺(NBS) 、 硫酸 、 过氧化苯甲酰 作用下， 以 甲醇 、 四氯化碳 、 丙酮 为溶剂， 反应 23.0h， 生成 2,2'-divinyl-4,4'-biphenol
  参考文献：
  名称：

  Shape-Persistent Macromolecular Disks from Reactive Supramolecular Rod Bundles

  摘要：

  We have synthesized a coil-rod-coil molecule based on a reactive rod block that self-organizes into a 3-D hexagonal close-packed (hcp) bundle structure in the melt state. Photo-cross-linking within an aromatic bundle yielded macromolecular disklike objects (molecular weight of 330 kDa) with a narrow size distribution that was essentially the same as that of the supramolecular bundles. In addition, cross-linking proceeded with the retention of the 3-D hcp symmetry of the supramolecular bundles. The 3-D symmetry of the macromolecular objects was observed to recover after their isolation from the solutions and transform into an isotropic liquid in the bulk state in a reversible way, suggesting that the macromolecular objects are shape-persistent in solutions as well as an isotropic liquid phase of the bulk.

  DOI：

  10.1021/ja0465552
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 2,2-二甲基-4,4-联苯二醇
  参考文献：
  名称：

  Schultz; Rhode, Chemisches Zentralblatt, 1902, vol. 73, # II, p. 1447

  摘要：

  DOI：

文献信息

• METHOD FOR PREPARING HYDROQUINONES AND DIHYDROXYBIPHENYL COMPOUNDS FROM MIXTURES OF BROMOPHENOLS AND BENZOQUINONES
  申请人：General Electric Company

  公开号：US20040199027A1

  公开（公告）日：2004-10-07

  A method is described for the simultaneous preparation of p-bromophenols and p-benzoquinones, intermediates useful in the preparation of hydroquinones and 4,4′-dihydroxybiphenyls, respectively. Hydroquinones and 4,4′-dihydroxybiphenyls are useful monomers for the preparation of a variety of polymers. The method also comprises reducing the p-benzoquinone to its corresponding hydroquinone in the presence of the p-bromophenol. Limiting the amount of HBr present in the reaction mixture was shown to control the amount of benzoquinone produced. The method also allows for the recycling of many of the reagents used, thereby reducing the cost of producing each monomer.

  描述了一种同时制备对溴苯酚和对苯醌的方法，这些中间体在制备对羟基苯酚和4,4'-二羟基联苯中很有用。对羟基苯酚和4,4'-二羟基联苯是制备各种聚合物的有用单体。该方法还包括在对溴苯酚存在的情况下将对苯醌还原为其相应的对羟基苯酚。据显示，限制反应混合物中存在的HBr的量可以控制产生的苯醌的量。该方法还允许回收使用的许多试剂，从而降低生产每种单体的成本。
• Synthesis and self-assembly of coil–rod–coil molecules with lateral methyl and ethyl groups in the center of the rod segment
  作者：Lirong Tian、Ke-Li Zhong、Yuanjuan Liu、Zhegang Huang、Long Yi Jin、Linda S. Hirst

  DOI：10.1039/c0sm00147c

  日期：——

  state reveals that side chains, methyl and ethyl groups in the middle of the rod segment, dramatically influence the self assembly behavior in the liquid-crystalline phase. Molecules containing a lateral methyl group based on PEO coil chain (DP of 12 and 17) self-organize into a hexagonally perforated layer (HPL) structure in the liquid- crystalline phase, while the molecule with a lateral ethyl group

  棒-螺旋分子由柔性和刚性嵌段组成，具有很强的自组装能力，可以以大块状态自组装成各种有序的纳米结构。在本文中，我们报告了线圈-棒-线圈低聚物的自组装行为的合成和表征。这些新材料由5个联苯醚键连接在一起的五个联苯组成一个杆段，并在杆组成单元和聚环氧乙烷的中心并入了侧向的甲基或乙基（聚醚）的聚合度（DP）为7、12和17个线圈段。通过差示扫描量热法（DSC）和X射线散射（XRD）在本体状态下对这些分子进行结构研究，发现杆段中间的侧链，甲基和乙基极大地影响了分子的自组装行为。液晶相。含有侧甲基的分子基于聚醚 盘绕链（DP为12和17）在液晶相中自组织为六边形穿孔层（HPL）结构，而带有侧向乙基的分子基于 聚醚线圈链（DP为7）自组装为二维矩形柱状液晶结构。随着含乙基分子的线圈长度的进一步增加，分子在结晶相中自组织成一维层状结构。
• Process for the recovery of dihydroxybiaryl compounds
  申请人：Ofori Yaw John

  公开号：US20050075519A1

  公开（公告）日：2005-04-07

  A method for preparing and isolating dihydroxybiaryl compounds, such as 4,4′-dihydroxybiphenyl, is disclosed. The alkali metal salt of the dihydroxybiaryl compound is protonated with the monohydroxyaryl halide compound initially used in the reductive coupling reaction which produced the alkali metal salt. In addition, the alkali metal salt of the monohydroxyaryl halide compound is produced by the process, which can then be recycled as the base and monohydroxyaryl halide in a further reductive coupling reaction to form the alkali metal salt of the dihydroxybiaryl compound.

  本发明公开了一种制备和分离二羟基联芳烃化合物的方法，例如4,4'-二羟基联苯。该方法是通过用最初在还原偶联反应中用于生成碱金属盐的单羟基芳基卤化物化合物质子化二羟基联芳烃化合物的碱金属盐。此外，该过程还产生了单羟基芳基卤化物的碱金属盐，该碱金属盐可以作为基础和单羟基芳基卤化物在进一步还原偶联反应中再生产碱金属盐的二羟基联芳烃化合物。
• Thermotropic liquid crystalline aromatic polyesters
  申请人：Montedison S.p.A.

  公开号：EP0323710A1

  公开（公告）日：1989-07-12

  Thermotropic liquid crystalline aromatic polyesters comprise: (a) units derived from one or more dicarboxylic aromatic acids of the formula: HOOC-Ar₁-O-Ar₂-COOH      (1) in which: Ar₁    is a divalent aromatic radical consisting of one ring, or of a plurality of condensed, partially codensed or non condensed rings, containing from 6 to 18 carbon atoms, and which may be substituted Ar₂    is a divalent aromatic radical consisting of a plurality of condensed, partially condensed or non-condensed rings, containing from 12 to 18 (b) units derived from one or more aromatic diols of the formula: HO-Ar₃-OH      (2) in which Ar₃    is a divalent aromatic radical consisting of one ring, or of a plurality of condensed, partially condensed or non-condensed rings, containing from 6 to 18 carbon atoms, and which may be substituted and if desired, units derived from one or more other aromatic diacids and/or hydroxy acids of the formulae: (c)      HOOC-Ar₃-COOH      (3) (in which Ar₃ is as defined above), and (d)      HO-Ar₃-(CH=CH)n-COOH      (4) (in which Ar₃ is as defined above and n is 0 or 1).

  热致液晶芳香族聚酯包括： (a) 由一个或多个公式为：HOOC-Ar₁-O-Ar₂-COOH（1）的二元芳香族酸衍生的单元，其中： Ar₁是一个二价的芳香基团，包含一个环或多个凝聚的、部分凝聚的或非凝聚的环，含有6到18个碳原子，并且可以被取代； Ar₂是一个二价的芳香基团，包含多个凝聚的、部分凝聚的或非凝聚的环，含有12到18个碳原子。 (b) 由一个或多个公式为：HO-Ar₃-OH（2）的芳香族二元醇衍生的单元，其中 Ar₃是一个二价的芳香基团，包含一个环或多个凝聚的、部分凝聚的或非凝聚的环，含有6到18个碳原子，并且可以被取代。 如果需要，还可以包括由一个或多个其他芳香族二元酸和/或羟基酸的公式衍生的单元： (c) HOOC-Ar₃-COOH（3）（其中Ar₃如上所定义）和 (d) HO-Ar₃-（CH=CH）n-COOH（4）（其中Ar₃如上所定义，n为0或1）。
• 一种甲酚制备联苯二酚的方法
  申请人：中国科学院大连化学物理研究所

  公开号：CN114181047A

  公开（公告）日：2022-03-15

  本发明涉及一种甲酚类化合物制备联苯二酚的方法。该方法以光能为能量，在半导体光催化剂的催化作用下，即可将甲酚转化为联苯二酚。其反应过程如下：将甲酚，半导体光催化剂和溶剂混合后，加入到耐压石英容器(>1MPa)中并用惰性气体置换。常温光照搅拌，反应时间大于或等于1小时。反应结束后催化剂与反应体系通过过滤分离，并可多次循环使用。反应产物通过结晶分离，联苯二酚的选择性可达61％。该方法制备的联苯二酚化合物可作为抗氧化剂及替代双酚A制备聚碳酸酯。