2,4,5-三氨基甲苯 | 27530-46-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2,4,5-三氨基甲苯
• 中文别名: 6-脱氧-3-C-甲基-2-O-甲基六糖
• 英文名称: 5-methyl-benzene-1,2,4-triyltriamine
• 英文别名: 5-Methyl-benzen-1,2,4-triyltriamin；2.4.5-Triamino-toluol；5-methyl-1,2,4-triamino-benzene；5-methyl-1,2-4-triamino-benzene；1,2,4-Benzenetriamine, 5-methyl-；5-methylbenzene-1,2,4-triamine
• CAS: 27530-46-7
• 化学式: C₇H₁₁N₃
• mdl: MFCD01658127
• 分子量: 137.184
• InChiKey: DUPRNVZNPMWDDU-UHFFFAOYSA-N

物化性质

• 沸点：
  337.6±37.0 °C(Predicted)
• 密度：
  1.218±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.142
• 拓扑面积：
  78.1
• 氢给体数：
  3
• 氢受体数：
  3

安全信息

• 海关编码：
  2921590090

反应信息

• 作为反应物：
  描述：

  2,4,5-三氨基甲苯 在 selenium(IV) oxide 作用下， 生成 6-methyl-benzo[1,2,5]selenadiazol-5-ylamine
  参考文献：
  名称：

  Efros; El'zow, Zhurnal Obshchei Khimii, 1958, vol. 28, p. 2172; engl. Ausg. S. 2211

  摘要：

  DOI：
• 作为产物：
  描述：

  对苯二甲酸 在 镍 作用下， 以 水 为溶剂， 生成 2,4,5-三氨基甲苯
  参考文献：
  名称：

  Process for the preparation of triamino benzenes by catalytic

  摘要：

  通过在含有至少一个摩尔等量的单酸或二酸的水中对2,4-二硝基苯胺进行催化氢化，可以高产高纯度地得到1,2,4-三氨基苯。这些产物被认为是染料和生物杀菌剂的中间体，具有重要的用途。

  公开号：

  US04141917A1

文献信息

• [EN] KETAL ESTER DERIVATIVES<br/>[FR] DÉRIVÉS CÉTO-ESTERS
  申请人：SEGETIS INC

  公开号：WO2010036884A1

  公开（公告）日：2010-04-01

  The present disclosure relates to the preparation of acrylate, alkacrylate, allyl, and polycarbonate derivatives of hydroxy ketal esters, and uses thereof.

  本公开涉及羟基缩醛酮酯的丙烯酸酯、烯丙酸酯、烯丙基和聚碳酸酯衍生物的制备以及它们的用途。
• [EN] KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS<br/>[FR] COMPOSÉS CÉTAL AMIDES, PROCÉDÉS DE FABRICATION ET APPLICATIONS
  申请人：SEGETIS INC

  公开号：WO2010075330A1

  公开（公告）日：2010-07-01

  Disclosed herein are ketal amide compounds. The ketal amide compounds are synthesized by the reaction of ketal acids or ketal esters with amine functional compounds. Also disclosed are methodologies useful to make the ketal amide compounds. Also disclosed herein are formulations and articles containing the ketal amide compounds.

  本文披露了酮缩酸或酮缩酯与胺官能化合物反应合成的酮酰胺化合物。还披露了用于制备酮酰胺化合物的有用方法。同时还披露了含有酮酰胺化合物的配方和制品。
• COMPOSITIONS AND METHODS COMPRISING CONDUCTIVE METAL ORGANIC FRAMEWORKS AND USES THEREOF
  申请人：Massachusetts Institute of Technology

  公开号：US20170073364A1

  公开（公告）日：2017-03-16

  Compositions and methods comprising metal organic frameworks (MOFs) and related uses are generally provided. In some embodiments, a MOF comprises a plurality of metal ions, each coordinated with at least one ligand comprising at least two sets of ortho-diimine groups arranged about an organic core.

  通常提供包括金属有机框架（MOFs）和相关用途的组合物和方法。在某些实施例中，MOF包括多个金属离子，每个离子都与至少一个配体配位，该配体包括至少两个正交二亚胺基团集合在有机核心周围。
• HETERO COMPOUND
  申请人：HARADA Hironori

  公开号：US20090076070A1

  公开（公告）日：2009-03-19

  [Problems] To provide a useful compound as an active ingredient for a preventing and/or treating agent for rejection in the transplantation of an organ, bone marrow, or a tissue, an autoimmune disease, or the like, which has an excellent S1P 1 agonist activity. [Means for Solving] Since the compound of the invention has an S1P 1 agonist activity, it is useful as an active ingredient for a treating or preventing agent for a disease caused by unfavorable lymphocytic infiltration, for example, an autoimmune disease such as graft rejection in the transplantation of an organ, bone marrow, or a tissue, a graft-versus-host disease, rheumatic arthritis, multiple sclerosis, systemic lupus erythematosus, a nephrotic syndrome, encephalomeningitis, myasthenia gravis, pancreatitis, hepatitis, nephritis, diabetes, pulmonary disorder, asthma, atopic dermatitis, inflammatory bowel disease, atherosclerosis, ischemia-reperfusion injury, or an inflammatory disease, and further, a disease caused by the abnormal growth or accumulation of cells such as cancer and leukemia.

  [问题] 提供一种有优异S1P1激动剂活性的化合物，作为器官、骨髓或组织移植、自身免疫性疾病等引起的排异的预防和/或治疗剂的有效活性成分。 [解决方法] 由于本发明的化合物具有S1P1激动剂活性，因此可用作治疗或预防由不良淋巴细胞浸润引起的疾病的活性成分，例如器官、骨髓或组织移植的移植排斥、移植物抗宿主病、风湿性关节炎、多发性硬化症、全身性红斑狼疮、肾病综合症、脑脊髓炎、重症肌无力、胰腺炎、肝炎、肾炎、糖尿病、肺部疾病、哮喘、特应性皮炎、炎症性肠病、动脉粥样硬化、缺血再灌注损伤或异常细胞生长或积累引起的癌症和白血病等疾病。
• POLYMERIZABLE-MONOMER-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME
  申请人：DIC Corporation

  公开号：EP3159393A1

  公开（公告）日：2017-04-26

  The problem to be solved by the present invention is to provide: a liquid crystal composition suitable for a liquid crystal display element which hardly generates drop marks in production without worsening various characteristics thereof as liquid crystal display elements such as dielectric anisotropy, viscosity, nematic phase upper limit temperature, low-temperature nematic phase stability, γ1 and others, and also burn-in characteristics of display elements, and which realizes a stable discharge amount of a liquid crystal material in an ODF process, and to provide a liquid crystal display element using the composition. The purpose of the present invention is to provide a liquid crystal composition provided with photosensitizing properties as the entire composition where a polymerizable monomer is combined with specific liquid crystal compounds.

  本发明要解决的问题是：提供一种适用于液晶显示元件的液晶组合物，该组合物在生产过程中几乎不会产生液滴痕迹，同时不会使其作为液晶显示元件的各种特性（如介电各向异性、粘度、向列相上限温度、低温向列相稳定性、γ1 等）以及显示元件的烧损特性恶化，并且能够在 ODF 工艺中实现稳定的液晶材料放电量，以及提供一种使用该组合物的液晶显示元件。本发明的目的是提供一种具有光敏特性的液晶组合物，作为可聚合单体与特定液晶化合物结合的整个组合物。