2,4-二氯-6-苯基苯氧基乙基胺 | 1422-18-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2,4-二氯-6-苯基苯氧基乙基胺
• 中文别名: 2,4-二氯-6-苯基苯氧基乙胺
• 英文名称: DPEA
• 英文别名: 2,4-Dichloro-6-phenylphenoxyethylamine；2-(2,4-Dichloro-6-phenylphenoxy)ethylamine；2-(2,4-dichloro-6-phenylphenoxy)ethanamine
• CAS: 1422-18-0
• 化学式: C₁₄H₁₃Cl₂NO
• 分子量: 282.169
• InChiKey: VPBHLDHENUNWHJ-UHFFFAOYSA-N

物化性质

• 沸点：
  150-160 °C(Press: 1 Torr)
• 密度：
  1.266±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  35.2
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2922199090

文献信息

• Affinity resins and their use in isolating bacterial luciferase
  申请人：THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

  公开号：EP0057600A2

  公开（公告）日：1982-08-11

  Novel affinity resins can be used for the isolation of bacterial luciferase, by saturating the resin with a sample containing bacterial luciferase suspended in an anionic buffer solution; washing the saturated resin with additional anionic buffer to remove unbound protein; eluting the washed saturated resin with a cationic buffer solution; and recovering the bacterial luciferase. Novel resins which can be used for this purpose comprise a support material, a spacer arm and a ligand, and are represented by formulae J, K and M.

  新型亲和树脂可用于分离细菌荧光素酶，具体方法是：用悬浮在阴离子缓冲溶液中含有细菌荧光素酶的样品使树脂饱和；用额外的阴离子缓冲溶液洗涤饱和树脂以除去未结合的蛋白质；用阳离子缓冲溶液洗脱洗涤后的饱和树脂；然后回收细菌荧光素酶。可用于此目的的新型树脂由支撑材料、间隔臂和配体组成，用式 J、K 和 M 表示。
• ANTIMICROBIAL THERAPY FOR BACTERIAL INFECTIONS
  申请人：The Regents of the University of California

  公开号：EP2020857A2

  公开（公告）日：2009-02-11
• Antimicrobial therapy for bacterial infections
  申请人：Nizet Victor

  公开号：US20090042976A1

  公开（公告）日：2009-02-12

  The disclosure provides a molecular genetic approach of targeted mutagenesis and heterologous expression, coupled with in vitro and in vivo models of bacterial pathogenesis, to demonstrate that the S. aureus pigment is a virulence factor and potential novel target for antimicrobial therapy.
• ANTIMICROBIAL COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS
  申请人：NIZET Victor

  公开号：US20140154302A1

  公开（公告）日：2014-06-05

  The disclosure provides compounds and methods to treat a microbial or a bacterial pathogenesis, and demonstrates that the S. aureus pigment is a virulence factor and potential novel target for antimicrobial therapy.
• US4412001A
  申请人：——

  公开号：US4412001A

  公开（公告）日：1983-10-25