2,6-二硝基-4-三氟甲基苯磺酸 | 54729-99-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2,6-二硝基-4-三氟甲基苯磺酸
• 英文名称: 2,6-Dinitro-4-trifluormethylbenzolsulfonsaeure
• 英文别名: 2,6-Dinitro-4-trifluormethylbenzolsulphonat；2,6-Dinitro-4-trifluoromethylbenzenesulfonic acid；2,6-dinitro-4-(trifluoromethyl)benzenesulfonic acid
• CAS: 54729-99-6
• 化学式: C₇H₃F₃N₂O₇S
• 分子量: 316.171
• InChiKey: IVFGXTYRSDHGSH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  154
• 氢给体数：
  1
• 氢受体数：
  10

安全信息

• 海关编码：
  2904909090

反应信息

• 作为产物：
  描述：

  4-氯-3,5-二硝基三氟甲苯 在 sodium sulfite 作用下， 生成 2,6-二硝基-4-三氟甲基苯磺酸
  参考文献：
  名称：

  用三氟甲基取代的芳基卤化物和磺酸盐修饰人血清白蛋白。

  摘要：

  DOI：

  10.1021/ja00834a029

文献信息

• METHOD FOR NON-ENZYMATIC COMBINATION OF NUCLEIC ACID CHAINS
  申请人：Japan Science and Technology Agency

  公开号：EP3187584A1

  公开（公告）日：2017-07-05

  Provided, as a technique for binding a nucleic acid chain and a nucleic acid chain by a natural structure or an analogous structure thereto, is a non-enzymatic nucleic acid chain binding method, which is a method for binding a nucleic acid chain and a nucleic acid chain not via an enzymatic reaction, including a step of reacting a nucleic acid chain having a phosphorothioate group and a nucleic acid chain having a hydroxyl group or amino group in the presence of an electrophile.

  作为一种通过天然结构或类似结构结合核酸链和核酸链的技术，提供了一种非酶结合核酸链的方法，它是一种不通过酶反应结合核酸链和核酸链的方法，包括在亲电子体存在的情况下，使具有硫代磷酸基的核酸链和具有羟基或氨基的核酸链发生反应的步骤。
• Histidine copolymer and methods for using same
  申请人：——

  公开号：US20030045465A1

  公开（公告）日：2003-03-06

  The invention provides a pharmaceutical agent delivery composition comprising: (i) a transport polymer comprising a linear or branched peptide having from about 10 to about 300 amino acid residues, having from about 5 to 100% histidine residues, and optionally having from 0 to about 95% non-histidine amino acid residues; (ii) at least one pharmaceutical agent; and optionally (iii) one or more intracellular delivery components in association with the transport polymer. The invention also provides methods for using such composition to deliver the pharmaceutical agent to the interior of cells.

  本发明提供了一种药剂递送组合物，该组合物包括：(i) 由线性或支链多肽组成的转运聚合物，该多肽具有约 10 至约 300 个氨基酸残基，组氨酸残基含量约为 5 至 100%，非组氨酸氨基酸残基含量可选为 0 至约 95%；(ii) 至少一种药剂；以及可选的(iii) 一种或多种与转运聚合物结合的细胞内递送组分。本发明还提供了使用这种组合物向细胞内部递送药剂的方法。
• HISTIDINE COPOLYMER AND METHODS FOR USING SAME
  申请人：Mixson, A. James

  公开号：EP1242052A1

  公开（公告）日：2002-09-25
• EP1242052A4
  申请人：——

  公开号：EP1242052A4

  公开（公告）日：2003-07-02
• Branched cationic copolymers and methods for antimicrobial use
  申请人：Mixson A J

  公开号：US20060281683A1

  公开（公告）日：2006-12-14

  The invention provides a branched copolymer for the treatment of bacterial, fungal, and viral infections. The branched copolymer is characterized as having (i) at least 10 amino acids, (ii) at least 10% of the amino acids are histidine, (iii) at least 10% of the amino acids are non-histidine, (iv) said branched polymer comprising one or more backbones, (v) one or more terminal branches, and (vi) optionally, one or more non-terminal branches.