2-(1-吡咯烷基)甲基丙烯酸

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 中文名称: 2-(1-吡咯烷基)甲基丙烯酸
• 中文别名: 2-吡咯烷-1-甲基丙烯酸
• 英文名称: 2-Pyrrolidin-1-ylmethyl-acrylic acid
• 英文别名: 2-(pyrrolidin-1-ium-1-ylmethyl)prop-2-enoate
• 化学式: C₈H₁₃NO₂
• 分子量: 155.197
• InChiKey: NJQWKGMEAUKIKT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  丙二酸 以73%的产率得到
  参考文献：
  名称：

  Krawczyk Henryk, Synth. Commun, 25 (1995) N 5, S 641-650

  摘要：

  DOI：

文献信息

• The Mannich Reaction of Malonic Acid. An Efficient Route to Some α-Functionalized Acrylates
  作者：Henryk Krawczyk

  DOI：10.1080/00397919508011401

  日期：1995.3

  Abstract Variousα-functionalized acrylates can be easily synthesized by means of the Mannich reaction of malonic acid with paraformaldehyde and secondary aliphatic amines.

  摘要 通过丙二酸与多聚甲醛和脂肪仲胺的曼尼希反应，可以很容易地合成各种α-官能化丙烯酸酯。
• ANTIFOULING COMPOSITION
  申请人：Jotun A/S

  公开号：EP3489311A1

  公开（公告）日：2019-05-29

  The present invention provides a copolymer comprising repeat units of formulae (A), (B1) and/or (B2) and optionally (C): wherein in formula (A) R is selected from H and C1-6 alkyl; X1 is selected from COO, CONH and OCO; m is 0 or 1; R1 is selected from substituted or unsubstituted, linear or branched, C1-8 alkylene; n is 0 or 1; and R2 is a substituted or unsubstituted heterocyclyl, NRxRy, NHCORx or CONRxRy, wherein Rx and Ry are independently selected from substituted or unsubstituted, linear or branched, C1-8 alkyl, in formulae (B1) and (B2) R is selected from H and C1-6 alkyl; X2 is selected from COOR3 and OCOR3; o is 0 or 1; R3 is selected from substituted or unsubstituted, linear or branched, C1-8 alkylene; each R4 is independently selected from C1-10 alkyl and C5-10 aryl; in formula (B1) q is an integer from 1 to 160, and in formula (B2) q is 0 or an integer from 1 to 80, R5 is selected from C1-10 alkyl, C5-10 aryl or O-Si(R6)3, wherein R6 is independently selected from C1-10 alkyl and C5-10 aryl; and in formula (C): R is selected from H and C1-6 alkyl; and X3 is selected from COOH, COOR7, OCOR7,OH or OR7 wherein R7 is selected from substituted or unsubstituted, linear or branched, C1-8 alkyl; wherein said copolymer comprises 1-40 wt% of repeat unit (A), a total of 10-90 wt% of repeat units (B1) and/or (B2) and 0 to 70 wt% of repeat unit (C).

  本发明提供了一种由式（A）、（B1）和/或（B2）以及可选的（C）的重复单元组成的共聚物： 其中 式 (A) 中 R 选自 H 和 C1-6 烷基； X1 选自 COO、CONH 和 OCO； m 为 0 或 1； R1 选自取代或未取代的、直链或支链 C1-8 烷基； n 为 0 或 1；以及 R2 是取代或未取代的杂环基、NRxRy、NHCORx 或 CONRxRy、 其中 Rx 和 Ry 独立地选自取代或未取代的、直链或支链 C1-8 烷基、 在式 (B1) 和 (B2) 中 R 选自 H 和 C1-6 烷基； X2 选自 COOR3 和 OCOR3； o 为 0 或 1； R3 选自取代或未取代的、直链或支链 C1-8 烷基； 每个 R4 独立选自 C1-10 烷基和 C5-10 芳基； 在式 (B1) 中 q 是 1 到 160 之间的整数、 在式 (B2) 中 q 是 0 或 1 至 80 的整数、 R5 选自 C1-10 烷基、C5-10 芳基或 O-Si(R6)3，其中 R6 独立地选自 C1-10 烷基和 C5-10 芳基；以及 在式 (C) 中 R 选自 H 和 C1-6 烷基；以及 X3 选自 COOH、COOR7、OCOR7、OH 或 OR7，其中 R7 选自取代或未取代、直链或支链 C1-8 烷基； 其中，所述共聚物包括 1-40 wt%的重复单元（A）、总共 10-90 wt%的重复单元（B1）和/或 （B2）以及 0-70 wt%的重复单元（C）。
• Krawczyk Henryk, Synth. Commun, 25 (1995) N 5, S 641-650
  作者：Krawczyk Henryk

  DOI：——

  日期：——
• [EN] ANTIFOULING COMPOSITION<br/>[FR] COMPOSITION ANTISALISSURE
  申请人：JOTUN AS

  公开号：WO2019101920A1

  公开（公告）日：2019-05-31

  The present invention provides a copolymer comprising repeat units of formulae (A), (B1 ) and/or (B2) and optionally (C): wherein in formula (A) R is selected from H and C1-6 alkyl; X1 is selected from COO, CONH and OCO; m is 0 or 1; R1 is selected from substituted or unsubstituted, linear or branched, C1-8 alkylene; n is 0 or 1; and R2 is a substituted or unsubstituted heterocyclyl, NRxRy, NHCORx or CONRxRy, wherein Rx and Ry are independently selected from substituted or unsubstituted, linear or branched, C1-8 alkyl, in formulae (B1 ) and (B2) R is selected from H and C1-6 alkyl; X2 is selected from COOR3 and OCOR3; o is 0 or 1; R3 is selected from substituted or unsubstituted, linear or branched, C1-8 alkylene; each R4 is independently selected from C1-10 alkyl and C5-10 aryl; in formula (B1 ) q is an integer from 1 to 160, and in formula (B2) q is 0 or an integer from 1 to 80, R5 is selected from C1-10 alkyl, C5-10 aryl or 0-Si(R6)3, wherein R6 is independently selected from C1-10alkyl and C5-10 aryl; and in formula (C): R is selected from H and C1-6 alkyl; and X3 is selected from COOH, COOR7, OCOR7,OH or OR7 wherein R7 is selected from substituted or unsubstituted, linear or branched, C1-8 alkyl; wherein said copolymer comprises 1 -40 wt% of repeat unit (A), a total of 10-90 wt% of repeat units (B1 ) and/or (B2) and 0 to 70 wt% of repeat unit (C).