2-(2-甲基烯丙基)四氢-2H-吡喃 | 67217-57-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 中文名称: 2-(2-甲基烯丙基)四氢-2H-吡喃
• 英文名称: 2-(2-methallyl)tetrahydro-2H-pyran
• 英文别名: Tetrahydro-2-(2-methyl-2-propen-1-yl)-2H-pyran；2-(2-methylprop-2-enyl)oxane
• CAS: 67217-57-6
• 化学式: C₉H₁₆O
• 分子量: 140.225
• InChiKey: GRYNYFQMSAYKER-UHFFFAOYSA-N

物化性质

• 沸点：
  184.1±9.0 °C(Predicted)
• 密度：
  0.860±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-甲氧基四氢吡喃 、 异丁烯基三甲基硅烷 、 乙酸酐 在 溴化铋 作用下， 反应 1.5h， 以30%的产率得到5-methoxy-7-methyloct-7-en-1-yl acetate
  参考文献：
  名称：

  Bismuth(III) bromide in organic synthesis. A catalytic method for the allylation of tetrahydrofuranyl and tetrahydropyranyl ethers

  摘要：

  A bismuth bromide-catalyzed (10.0 mol %) multicomponent reaction involving the allylation of THF- and THP-ethers, followed by in situ derivatization with acetic anhydride to generate highly functionalized esters has been developed under solvent-free conditions. To the best of our knowledge, this is the first report of a catalytic procedure for the allylation of THF- and THP-ethers to yield ring-opened products. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.08.079

文献信息

• Bismuth(III) bromide in organic synthesis. A catalytic method for the allylation of tetrahydrofuranyl and tetrahydropyranyl ethers
  作者：Scott W. Krabbe、Veronica V. Angeles、Ram S. Mohan

  DOI：10.1016/j.tetlet.2010.08.079

  日期：2010.10

  A bismuth bromide-catalyzed (10.0 mol %) multicomponent reaction involving the allylation of THF- and THP-ethers, followed by in situ derivatization with acetic anhydride to generate highly functionalized esters has been developed under solvent-free conditions. To the best of our knowledge, this is the first report of a catalytic procedure for the allylation of THF- and THP-ethers to yield ring-opened products. (C) 2010 Elsevier Ltd. All rights reserved.