2-(2-羟基-N-(2-羟基-4-碘苯基)-4-碘苯胺基)-5-碘苯酚 | 831220-48-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 2-(2-羟基-N-(2-羟基-4-碘苯基)-4-碘苯胺基)-5-碘苯酚
• 英文名称: (5,5',5''-triiodo-2,2',2''-triphenol)amine
• 英文别名: 2,2',2''-Nitrilotris(5-iodophenol)；2-(2-hydroxy-N-(2-hydroxy-4-iodophenyl)-4-iodoanilino)-5-iodophenol
• CAS: 831220-48-5
• 化学式: C₁₈H₁₂I₃NO₃
• 分子量: 671.012
• InChiKey: DZFSMPGBWLGHGH-UHFFFAOYSA-N

物化性质

• 熔点：
  184 °C
• 沸点：
  658.7±55.0 °C(Predicted)
• 密度：
  2.378±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  25
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  63.9
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  乙烯基三氯硅烷 、 2-(2-羟基-N-(2-羟基-4-碘苯基)-4-碘苯胺基)-5-碘苯酚 以 二丁醚 为溶剂， 反应 4.0h， 以49.2%的产率得到1-vinyl-((6,6',6''-triiodo)-3,4,6,7,10,11-tribenzo)silatrane
  参考文献：
  名称：

  The synthesis of bromo and iodo trifunctionalised tribenzosilatranes

  摘要：

  In this report we present a direct synthesis of bromo 8 and iodo 9 trisubstituted tribenzosilatranes. Cornmercially available o-anisidine I was transformed into the triarylamine 3 in a two-step sequence. which was halogenated to furnish;h the tribromo 4 or the triiodo 5 substituted triamines, respectively. Subsequent deprotection of the methyl ethers furnished the novel tripod ligands 6 and 7. A transilylation reaction in the last step led to the synthesis of the desired para-halogenated tribenzosilatrane 8 and 9. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2004.11.034
• 作为产物：
  描述：

  tris(2-methoxyphenyl)amine 在 碘 、 silver trifluoroacetate 、 三溴化硼 作用下， 以 二氯甲烷 为溶剂， 反应 20.67h， 生成 2-(2-羟基-N-(2-羟基-4-碘苯基)-4-碘苯胺基)-5-碘苯酚
  参考文献：
  名称：

  The synthesis of bromo and iodo trifunctionalised tribenzosilatranes

  摘要：

  In this report we present a direct synthesis of bromo 8 and iodo 9 trisubstituted tribenzosilatranes. Cornmercially available o-anisidine I was transformed into the triarylamine 3 in a two-step sequence. which was halogenated to furnish;h the tribromo 4 or the triiodo 5 substituted triamines, respectively. Subsequent deprotection of the methyl ethers furnished the novel tripod ligands 6 and 7. A transilylation reaction in the last step led to the synthesis of the desired para-halogenated tribenzosilatrane 8 and 9. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2004.11.034

文献信息

• The synthesis of bromo and iodo trifunctionalised tribenzosilatranes
  作者：Rubén Alvarez、Georg H. Mehl

  DOI：10.1016/j.tetlet.2004.11.034

  日期：2005.1

  In this report we present a direct synthesis of bromo 8 and iodo 9 trisubstituted tribenzosilatranes. Cornmercially available o-anisidine I was transformed into the triarylamine 3 in a two-step sequence. which was halogenated to furnish;h the tribromo 4 or the triiodo 5 substituted triamines, respectively. Subsequent deprotection of the methyl ethers furnished the novel tripod ligands 6 and 7. A transilylation reaction in the last step led to the synthesis of the desired para-halogenated tribenzosilatrane 8 and 9. (C) 2004 Elsevier Ltd. All rights reserved.