(RS)-1,1,1-trifluoro-2-(4-ethoxyphenyl)-3-(3-phenoxybenzyloxy)propane | 107714-62-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (RS)-1,1,1-trifluoro-2-(4-ethoxyphenyl)-3-(3-phenoxybenzyloxy)propane
• 英文别名: 2-(4-ethoxyphenyl)-3,3,3-trifluoro-1-(3-phenoxybenzyl)oxypropane；3-phenoxybenzyl 3,3,3-trifluoro-2-phenylpropyl ether；1,1,1-trifluoro-2-(4-ethoxyphenyl)-3-(3-phenoxybenzyloxy)propane；2-(4-ethoxyphenyl)-3,3,3-trifluoropropyl 3-phenoxybenzyl ether；1-ethoxy-4-[1,1,1-trifluoro-3-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene
• CAS: 107714-62-5
• 化学式: C₂₄H₂₃F₃O₃
• 分子量: 416.44
• InChiKey: ZLAFALWCDWDCIC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  30
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  (RS)-1,1,1-trifluoro-2-(4-ethoxyphenyl)-3-(3-phenoxybenzyloxy)propane 在 2-(2-cyanopropan-2-yldiazenyl)-2-methylpropanenitrile N-溴代丁二酰亚胺(NBS) 作用下， 以 四氯化碳 为溶剂， 生成 (2RS)-1,1,1-trifluoro-2-(4-ethoxyphenyl)-3-[(RS)-α-bromo-3-phenoxybenzyloxy]-propane
  参考文献：
  名称：

  Insecticidal ethers

  摘要：

  这项发明涉及新型氟化醚，可用作杀虫剂和杀螨剂，涉及其制备的工艺和中间体，涉及其杀虫和杀螨组合物，以及用于 bekämpfung 和控制昆虫和螨虫害的方法。

  公开号：

  US05225607A1
• 作为产物：
  描述：

  4-溴苯乙醚 在 盐酸 、 sodium hydroxide 、 sodium tetrahydroborate 、 四(三苯基膦)钯 、 四丁基溴化铵 作用下， 以 四氢呋喃 、 1,4-二氧六环 、 乙醚 为溶剂， 反应 12.0h， 生成 (RS)-1,1,1-trifluoro-2-(4-ethoxyphenyl)-3-(3-phenoxybenzyloxy)propane
  参考文献：
  名称：

  α-三氟甲基取代的β-乙氧基乙烯基锌试剂：制备和钯催化的交叉偶联，作为功能化CF（3）化合物的新型途径。

  摘要：

  DOI：

  10.1021/jo952215a

文献信息

• Novel ether compound, a process for manufacturing the same, a
  申请人：Sumitomo Chemical Company, Limited

  公开号：US04840971A1

  公开（公告）日：1989-06-20

  An ether compound represented by the following general formula (I), its produciton method and an insecticidal and/or acaricidal composition containing it as an active ingredient: ##STR1## wherein R.sub.1 and R.sub.2, which may be identical or different, represent a hydrogen or halogen atom or a lower alkyl, lower haloalkyl, lower alkoxyl, lower haloalkoxyl, lower alkenyl or lower alkenyloxyl group, or represent, taken together, methylenedioxy, lower alkylene, ethyleneoxy or lower alkylethyleneoxy group; R.sub.3 represents a hydrogen or fluorine atom; R.sub.4 represents a hydrogen or halogen atom or a lower alkyl, lower haloalkyl, lower alkoxyl or lower haloalkoxyl group; m represents an integer of 1 or 2; Y represents an oxygen or sulfur atom or a group represented by the formula --CH.sub.2 -- or --NH--; and Z represents a nitrogen atom or a group represented by the formula --CH.dbd., and its starting materials.

  由以下一般式(I)表示的醚类化合物，其生产方法以及含有其作为活性成分的杀虫和/或杀螨组合物： ##STR1## 其中，R.sub.1和R.sub.2可以相同或不同，表示氢或卤素原子或较低的烷基，较低的卤代烷基，较低的烷氧基，较低的卤代烷氧基，较低的烯基或较低的烯氧基基团，或表示一起取的亚甲二氧基，较低的烷基，乙烯氧基或较低的烷基乙烯氧基基团；R.sub.3表示氢或氟原子；R.sub.4表示氢或卤素原子或较低的烷基，较低的卤代烷基，较低的烷氧基或较低的卤代烷氧基基团；m表示1或2的整数；Y表示氧或硫原子或由公式--CH.sub.2--或--NH--表示的基团；Z表示氮原子或由公式--CH.dbd.表示的基团，以及其起始材料。
• Ether compounds, process for their preparation, compositions containing the same and use thereof
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0240978A2

  公开（公告）日：1987-10-14

  Ether compounds represented by the following general formula (I), their production and insecticidal and/or acaricidal compositions containing it as an active ingredient: wherein R, and R2, which may be identical or different, represent a hydrogen or halogen atom or a lower alkyl, lower haloalkyl, lower alkoxyl, lower haloalkoxyl, lower alkenyl or lower alkenyloxyl group, or represent, taken together, methylenedioxy, lower alkylene, ethyleneoxy or lower alkylethyleneoxy group; R3 represents a hydrogen or fluorine atom; R4 represents a hydrogen or halogen atom or a lower alkyl, lower haloalkyl, lower alkoxyl or lower haloalkoxyl group; m represents an integer of 1 or 2; Y represents an oxygen or sulfur atom or a group represented by the formula -CH2-or -NH-; and Z represents a nitrogen atom or a group represented by the formula -CH =, and starting materials.

  由以下通式(I)代表的醚类化合物、其生产以及含有该化合物作为活性成分的杀虫和/或杀螨剂组合物： 其中，R 和 R2（可以相同或不同）代表氢原子或卤素原子或低级烷基、低级卤代烷基、低级烷氧基、低级卤代烷氧基、低级烯基或低级烯酰氧基，或同时代表亚甲基二氧基、低级亚烷基、亚乙基氧基或低级亚烷基乙氧基；R3 代表氢原子或氟原子；R4 代表氢原子或卤素原子或低级烷基、低级卤代烷基、低级烷氧基或低级卤代烷氧基；m 代表 1 或 2 的整数；Y 代表氧原子或硫原子或由式 -CH2- 或 -NH- 代表的基团；Z 代表氮原子或由式 -CH = 代表的基团，以及起始原料。
• Process for intermediates for insecticidal compounds
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0280383A1

  公开（公告）日：1988-08-31

  The invention provides novel compounds of formula I, useful as intermediates for insecticidal ethers, wherein W represents 1 to 4 substituents selected from halo, alkyl, alkoxy, haloalkyl, haloalkoxy and alkoxyalkyl, or W represents a bidentate alkylene or alkylenedioxy group linking adjacent carbon atoms, X represents fluoroalkyl, and Y is selected from chlorine, bromine and alkoxy; and a process for preparing said ethers. The compounds of formula I are prepared by reacting a ketone of formula: with a phosphonium salt of formula Hal⁻ (Q)₃P⁺-CH₂-Y, where Hal⁻ represents a halide ion and Q represents alkyl or aryl.

  本发明提供了可用作杀虫醚中间体的新型式 I 化合物，其中 W 代表 1 至 4 个选自卤代、烷基、烷氧基、卤代烷基、卤代烷氧基和烷氧基烷基的取代基，或 W 代表连接相邻碳原子的双叉亚烷基或亚烷基二氧基基团，X 代表氟代烷基，Y 选自氯、溴和烷氧基；以及制备所述醚的工艺。 式 I 化合物通过使式：的酮与式 Hal- (Q)₃P⁺-CH₂-Y 的鏻盐反应制备，其中 Hal- 代表卤离子，Q 代表烷基或芳基。
• Insecticidal compositions
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0415568A2

  公开（公告）日：1991-03-06

  The invention provides insecticidal compositions for use in the application of insecticides to paddy-field rice, comprising a solid carrier, at least one insecticidal active ingredient, and a water-immiscible oil, said water-immiscible oil being a straight or branched chain, saturated or unsaturated C₈₋₁₈ alcohol or a lower alkyl ester of a straight or branched chain, saturated or unsaturated C₈₋₁₈ monocarboxylic acid, said water-immiscible oil being miscible with the insecticidal active ingredient and having a specific gravity of less than 1 and a boiling point at atmospheric pressure of greater than 200°C. The invention also provides processes for their preparation and a method of controlling insect pests of rice in a paddy-field.

  本发明提供了用于在稻田施用杀虫剂的杀虫组合物，该组合物包括固体载体、至少一种杀虫活性成分和水溶性油，所述水溶性油是直链或支链的饱和或不饱和C₈₋₁₈醇或直链或支链的低级烷基酯、直链或支链、饱和或不饱和 C₈₋₁₈醇或直链或支链、饱和或不饱和 C₈₋₁₈单羧酸的低级烷基酯、所述不溶于水的油与杀虫活性成分混溶，比重小于 1，常压下沸点大于 200°C。本发明还提供了其制备工艺和一种防治稻田中水稻害虫的方法。
• Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0545891A2

  公开（公告）日：1993-06-09

  The present invention relates to aldehyde compounds represented by the general formula (I) wherein R₁ and R₂, which may be identical or different, represent a hydrogen or halogen atom or a C₁₋₅ alkyl, C₁₋₅-haloalkyl, C₁₋₅-alkoxyl, C₁₋₅-haloalkoxyl, C₂₋₅-alkenyl or C₂₋₅-alkenyloxyl group, or represent, taken together, a methylenedioxy, C₃₋₄-alkylene, ethyleneoxy or C₁₋₅-alkylethyleneoxy group with the proviso that when R₁ and R₂ are identical they are not hydrogen atoms. These compounds are valuable intermediates for the production of insecticidal and/or acaricidal ether compounds.

  本发明涉及通式 (I) 所代表的醛化合物 其中 R₁ 和 R₂ 可以相同或不同，代表氢原子或卤素原子或 C₁₋₅ 烷基、C₁₋₅-卤代烷基、C₁₋₅-烷氧基、C₁₋₅-卤代烷氧基、C₂₋₅-烯基或 C₂₋₅-烯氧基、或共同代表亚甲基二氧基、C₃₋₄-亚烷基、乙烯氧基或 C₁₋₅-烷基乙烯氧基，但当 R₁ 和 R₂ 相同时，它们不是氢原子。 这些化合物是生产杀虫和/或杀螨醚化合物的重要中间体。