2-hydroxyethyl 3-methylbenzoate | 70192-58-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-hydroxyethyl 3-methylbenzoate
• CAS: 70192-58-4
• 化学式: C₁₀H₁₂O₃
• mdl: MFCD20257333
• 分子量: 180.203
• InChiKey: NEKGHNXKFVBGAV-UHFFFAOYSA-N

物化性质

• 沸点：
  313.4±25.0 °C(Predicted)
• 密度：
  1.143±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  乙二醇 、 间甲基苯腈 反应 96.0h， 生成 2-hydroxyethyl 3-methylbenzoate
  参考文献：
  名称：

  446.腈的非催化醇解

  摘要：

  DOI：

  10.1039/jr9630002417

文献信息

• Esterification of Aldehydes and Alcohols with Pyridinium Hydrobromide Perbromide in Water
  作者：Shinsei Sayama、Tetsuo Onami

  DOI：10.1055/s-2004-835630

  日期：——

  The direct esterification of aldehydes and alcohols was carried out with pyridinium hydrobromide perbromide in water at room temperature. A variety of aldehydes were converted to respective ester derivatives with alcoholssuch as methanol, 1,2-ethanediol, 1,3-propanediol. Further, a variety of aliphatic alcohols were also converted to the corresponding Tishchenko-like dimeric esters in good yields under

  醛和醇的直接酯化反应在室温下用过溴化氢溴化吡啶鎓在水中进行。多种醛与醇例如甲醇、1,2-乙二醇、1,3-丙二醇转化为各自的酯衍生物。此外，在相同的反应条件下，各种脂肪醇也以良好的产率转化为相应的 Tishchenko 样二聚酯。
• Electrochemical esterification reaction of alkynes with diols <i>via</i> cleavage of carbon–carbon triple bonds without catalyst and oxidant
  作者：Pei-Long Wang、Hui-Zhi Shen、Hui-Hui Cheng、Hui Gao、Pin-Hua Li

  DOI：10.1039/d0gc02193h

  日期：——

  as it is catalyst-free, oxidant-free, and additive-free and shows atom-economy. This is the first example of an electrochemical reaction via cleavage of carbon–carbon triple bonds. Meanwhile, this is also the first example of a carbon–carbon triple bond cleavage reaction of alkynes with diols.

  开发了一种新型的炔烃电化学酯化反应，用于酯的合成，其中二醇及其衍生物用作伙伴。该方法是绿色的，因为它不含催化剂，不含氧化剂和添加剂，并且具有原子经济性。这是通过裂解碳-碳三键进行电化学反应的第一个例子。同时，这也是炔烃与二醇的碳-碳三键裂解反应的第一个例子。
• Highly Selective Methodology for the Direct Conversion of Aromatic Aldehydes to Glycol Monoesters
  作者：Hashem Sharghi、Mona Hosseini Sarvari

  DOI：10.1021/jo020724o

  日期：2003.5.1

  Al(2)O(3)/MeSO(3)H (AMA) was found to be an extremely efficient reagent for the conversion of aromatic aldehydes and diols to glycol monoesters. The remarkable selectivity achieved with this reagent is an attractive feature of the present method.

  发现Al（2）O（3）/ MeSO（3）H（AMA）是将芳族醛和二醇转化为乙二醇单酯的极为有效的试剂。用这种试剂达到的显着选择性是本方法的一个吸引人的特征。
• Process for producing organic compound epoxy resin composition, cured article obtained from the epoxy resin, and semiconductor device obtained with epoxy resin
  申请人：——

  公开号：US20040260039A1

  公开（公告）日：2004-12-23

  There are disclosed a process for producing an organic compound in the presence of a particular substituted triarylphosphine compound, particularly, a process for producing an oxyalkylene derivative at a high yield using the above compound which is very active and easy to handle, by reacting an organic epoxy compound with a carboxylic acid ester, a carboxylic acid anhydride, a sulfonic acid ester or a carbonic acid ester, and an epoxy resin composition using a particular substituted triarylphosphine compound as a curing accelerator, a cured material of the composition and a semiconductor device using the composition.

  本文披露了一种在特定取代三芳基膦化合物存在下生产有机化合物的工艺，特别是一种使用上述化合物作为催化剂，通过将有机环氧化合物与羧酸酯、羧酸酐、磺酸酯或碳酸酯反应，以及使用特定取代三芳基膦化合物作为固化促进剂的环氧树脂组合物的工艺，从而高产地生产氧代烷基衍生物，还包括该组合物的固化材料和使用该组合物的半导体器件。
• IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
  申请人：Alcouffe Chantal

  公开号：US20130116250A1

  公开（公告）日：2013-05-09

  The invention relates to compounds corresponding to formula (I): in which R 2 and R 3 together form, with the carbon atoms of the phenyl nucleus to which they are attached, a 6-membered nitrogenous heterocycle corresponding to one of formula (A), (B) or (C) below: in which the wavy lines represent the phenyl nucleus to which R 2 and R 3 are attached. Preparation process and therapeutic use.

  该发明涉及与公式（I）相对应的化合物： 其中R2和R3与它们所附着的苯环的碳原子一起形成一个6元杂氮杂环，该杂环相当于下列公式（A）、（B）或（C）之一： 其中波浪线代表R2和R3所附着的苯环。 制备过程和治疗用途。