thioacetic acid S-[2-(2-acetylsulfanyl-ethylsulfanyl)-thioethyl] ester | 56015-80-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 硫代羧酸及其衍生物
• 英文名称: thioacetic acid S-[2-(2-acetylsulfanyl-ethylsulfanyl)-thioethyl] ester
• 英文别名: bis-(2-acetylsulfanyl-ethyl)-disulfide；Bis-(2-acetylmercapto-aethyl)-disulfid；thioacetic acid S-[2-(2-acetylsulfanyl-ethyldisulfanyl)-ethyl] ester；2,2'-Bis(acetylthio)diethyl disulfide；S-[2-(2-acetylsulfanylethyldisulfanyl)ethyl] ethanethioate
• CAS: 56015-80-6
• 化学式: C₈H₁₄O₂S₄
• 分子量: 270.462
• InChiKey: UIDUHHDZZGVYII-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  14
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  135
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  ethanedithiol monoacetate 在 溴 、 potassium carbonate 作用下， 以 二氯甲烷 、 水 为溶剂， 以88%的产率得到thioacetic acid S-[2-(2-acetylsulfanyl-ethylsulfanyl)-thioethyl] ester
  参考文献：
  名称：

  Cyclodextrin Dimers as Cleavable Carriers of Photodynamic Sensitizers

  摘要：

  Several phthalocyanines carrying hydrophobic components have been synthesized and shown to bind to a group of cyclodextrin dimers with a carbon-carbon double bond in the linker. The complexes are soluble in water. On irradiation in the presence of oxygen, the singlet oxygen produced cleaves the olefinic linkers in the complexes, resulting in precipitation of the sensitizers. This process concentrates the sensitizers in the light beam, a process that has useful potential in photodynamic therapy.

  DOI：

  10.1021/ja011709o

文献信息

• Beta-cyclodextrin dimers and phthalocyanines and uses thereof
  申请人：——

  公开号：US20030134824A1

  公开（公告）日：2003-07-17

  The invention provides &bgr;-cyclodextrin dimers and phthalocyanines which can be used in photodynamic therapy of cancer.

  这项发明提供了可用于癌症光动力疗法的β-环糊精二聚体和酞菁化合物。
• LUBRICATING OIL COMPOSITION
  申请人：Idemitsu Kosan Co., Ltd.

  公开号：EP2508590A1

  公开（公告）日：2012-10-10

  A lubricating oil composition which is excellent in wear resistance, despite its low phosphorus content, low sulfur content and low sulfuric acid ash content, and which exhibits excellent friction reducing effect even when used for a DLC-treated sliding part, is provided by compounding a specific sulfur-containing compound and a specific polar group-containing compound in a base oil.

  通过在基础油中加入特定的含硫化合物和特定的含极性基团化合物，提供了一种尽管磷含量低、硫含量低和硫酸灰分含量低，但却具有优异耐磨性的润滑油组合物，该组合物即使用于经 DLC 处理的滑动部件也能表现出优异的减摩效果。
• Reaction for nucleophilic opening of thiirane ring by thiols
  作者：A. V. Fokin、A. F. Kolomiets、L. S. Rudnitskaya、V. I. Shevchenko

  DOI：10.1007/bf00927483

  日期：1975.3
• Ray; Mitra, Journal of the Indian Chemical Society, 1929, vol. 6, p. 866
  作者：Ray、Mitra

  DOI：——

  日期：——
• [EN] BETA-CYCLODEXTRIN DIMERS AND PHTHALOCYANINES AND USES THEREOF<br/>[FR] DIMERES DE BETA-CYCLODEXTRINE ET PHTHALOCYANINES, ET LEURS UTILISATIONS
  申请人：UNIV COLUMBIA

  公开号：WO2003052060A2

  公开（公告）日：2003-06-26

  The invention provides β-cyclodextrin dimers and phthalocyanines which can be used in photodynamic therapy of cancer.