2-(4-氯苯基)-3-硝基丙烷-1-胺 | 149172-64-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-(4-氯苯基)-3-硝基丙烷-1-胺
• 英文名称: Benzeneethanamine, 4-chloro-beta-(nitromethyl)-
• 英文别名: 2-(4-chlorophenyl)-1-nitropropan-1-amine
• CAS: 149172-64-5
• 化学式: C9H11ClN2O2
• 分子量: 214.65
• InChiKey: DJKBPQPMXQDZEX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  71.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• EP1401423A4
  申请人：——

  公开号：EP1401423A4

  公开（公告）日：2006-08-16
• METHOD OF TREATING GASTROESOPHAGEAL REFLUX DISEASE AND NOCTURNAL ACID BREAKTHROUGH
  申请人：Depomed development Ltd

  公开号：EP1401423A1

  公开（公告）日：2004-03-31
• PHARMACEUTICAL DOSAGE FORMS HAVING IMMEDIATE RELEASE AND/OR CONTROLLED RELEASE PROPERTIES THAT CONTAIN A GABA<SB>B</SB> RECEPTOR AGONIST
  申请人：Impax Laboratories, Inc.

  公开号：EP1729740A2

  公开（公告）日：2006-12-13
• Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
  申请人：Buhr Wilm

  公开号：US20060241134A1

  公开（公告）日：2006-10-26

  The invention relates to the combination of certain active compounds from the acid pump antagonist class and compounds which modify gastrointestinal motility.
• [EN] METHOD OF TREATING GASTROESOPHAGEAL REFLUX DISEASE AND NOCTURNAL ACID BREAKTHROUGH<br/>[FR] METHODE DE TRAITEMENT DE REFLUX GASTROESOPHAGIEN PATHOLOGIQUE ET DE SECRETION D'ACIDE NOCTURNE
  申请人：DEPOMED DEV LTD

  公开号：WO2002096404A1

  公开（公告）日：2002-12-05

  A method of concurrent treatment for gastroesophageal reflux disease and nocturnal acid breakthrough is described, which comprises the delivery of an GABAb receptor agonist such as 4-amino-3-(4-chlorophenyl) butanoic acid, in the evening, in a gastric retained drug delivery system.