benzophenone radical-anion | 4460-50-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: benzophenone radical-anion
• CAS: 4460-50-8
• 化学式: C₁₃H₁₀KO
• 分子量: 221.32
• InChiKey: ZMZIEZHJTIVGGP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.54
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  benzophenone radical-anion 在 air 、 氢化钾 、 N,N,N-trimethylphenylammonium perchlorate 作用下， 以 四氢呋喃 为溶剂， 反应 30.5h， 生成 Dipotassium benzophenone dianion
  参考文献：
  名称：

  Selivanov, B. A.; Bil'kis, I. I.; Danilov, I. S., Journal of Organic Chemistry USSR (English Translation), 1982, vol. 18, # 10, p. 1888 - 1896

  摘要：

  DOI：
• 作为产物：
  描述：

  Dipotassium benzophenone dianion 在 air 、 氢化钾 作用下， 以 四氢呋喃 为溶剂， 反应 27.5h， 生成 benzophenone radical-anion
  参考文献：
  名称：

  Selivanov, B. A.; Bil'kis, I. I.; Danilov, I. S., Journal of Organic Chemistry USSR (English Translation), 1982, vol. 18, # 10, p. 1888 - 1896

  摘要：

  DOI：

文献信息

• Catalysts
  申请人：——

  公开号：US20030225275A1

  公开（公告）日：2003-12-04

  The invention describes ligands of formula (I), wherein LIG represents an &eegr; 5 -ligand substituted by a group R 1 and a group (R″) m ; X represents a 1 to 3 atom bridge; Y represents a nitrogen or phosphorus atom; Z represents a carbon, nitrogen or phosphorus atom.

  该发明描述了化合物的配体（I）的结构，其中LIG代表一个由基团R1和基团（R″）m取代的&eegr;5-配体；X代表1至3个原子的桥；Y代表一个氮或磷原子；Z代表一个碳、氮或磷原子。
• Use of sulfur containing initiators for anionic polymerization of monomers
  申请人：Hogan E Terrence

  公开号：US20060030657A1

  公开（公告）日：2006-02-09

  An initiator is presented for anionically polymerizing monomers, to provide a functional head group on the polymer. A polymer having a functional head group derived from a sulfur containing anionic initiator, and optionally as additional functional group resulting from the use of a functional terminating reagent, coupling agent or linking agent is also provided. A method is presented for anionically polymerizing monomers comprising the step of polymerizing the monomers with a sulfur containing anionic initiator to provide a functional head group on the polymer. An elastomeric compound, comprising a functional polymer and filler is also described. Also provided is a tire having decreased rolling resistance resulting from a tire component containing a vulcanizable elastomeric compound.

  提供了一种用于阴离子聚合单体的引发剂，以在聚合物上提供一个功能性头基团。还提供了一种具有源自含硫阴离子引发剂的功能性头基团的聚合物，以及根据使用功能性终止试剂、偶联剂或连接剂而产生的额外功能性基团。还提供了一种用于阴离子聚合单体的方法，包括使用含硫阴离子引发剂聚合单体的步骤，以在聚合物上提供一个功能性头基团。还描述了一种包含功能性聚合物和填料的弹性化合物。还提供了一种具有减少滚动阻力的轮胎，其轮胎部件含有可硫化的弹性化合物。
• Branched amino acids
  申请人：——

  公开号：US20030171434A1

  公开（公告）日：2003-09-11

  The invention relates to novel branched amino acids and novel methods for their production. The amino acids are useful in the preparation of non-natural peptides and peptidomimetics, by efficient synthesis methodology allowing good enantiomeric specificity at the alpha carbon. Typically the stereochemistry at the alpha carbon is at least 85%, preferably at least 95%, such as in excess of 99% enantiomerically pure. L-stereochemistry at this location is convenient as most biological interactions will favour this configuration, but the invention also extends to enantiomerically enriched and preferably at least 85%, preferably at least 95% such as at least 99% enantiomerically pure D stereoconfiguration. Compounds of the invention will find utility in the preparation of non-natural peptides and peptidomimetics, such as those used in the exploration of receptor specificity and activity or in peptidomimetic inhibitors of enzyme function. The compounds of the invention are built into such peptides/peptidomimetics using standard peptide chemistry.

  该发明涉及新型分支型氨基酸及其制备的新方法。这些氨基酸在非天然肽和肽类似物的制备中非常有用，通过高效的合成方法，在α碳处具有良好的对映体特异性。通常，α碳的立体化学至少为85％，最好至少为95％，例如超过99％的对映纯。在这个位置的L-立体化学很方便，因为大多数生物相互作用都会偏向于这种配置，但该发明也扩展到对映富集的、优选至少为85％、最好至少为95％，例如至少为99％的对映纯D立体构型。该发明的化合物将在标准肽化学中被构建成这样的肽/肽类似物。该发明的化合物将在非天然肽和肽类似物的制备中发挥作用，例如在探索受体特异性和活性或肽类似物酶功能抑制剂中使用。
• Diagnostic imaging contrast agents with extended blood retention
  申请人：——

  公开号：US20020164289A1

  公开（公告）日：2002-11-07

  The present invention relates to contrast agents for diagnostic imaging with prolonged blood retention. In particular, this invention relates to novel compounds that are characterized by an image enhancing moiety (IEM); a protein plasma binding moiety (PPBM); and a blood half-life extending moiety (BHEM). This invention also relates to pharmaceutical compositions comprising these compounds and to methods of using the compounds and compositions for blood half-life extension and contrast enhancement of diagnostic imaging.

  本发明涉及用于诊断成像的对比剂，其具有延长血液滞留时间的特性。特别地，本发明涉及新型化合物，其特征在于具有图像增强基团（IEM）；蛋白质血浆结合基团（PPBM）；以及延长血液半衰期的基团（BHEM）。本发明还涉及包含这些化合物的药物组合物，以及使用这些化合物和组合物进行血液半衰期延长和诊断成像对比增强的方法。
• Diagnostic Imaging Contrast Agents with Extended Blood Retention
  申请人：McMurry Thomas J.

  公开号：US20120107249A1

  公开（公告）日：2012-05-03

  The present invention relates to contrast agents for diagnostic imaging with prolonged blood retention. In particular, this invention relates to novel compounds that are characterized by an image enhancing moiety (IEM); a protein plasma binding moiety (PPBM); and a blood half-life extending moiety (BHEM). This invention also relates to pharmaceutical compositions comprising these compounds and to methods of using the compounds and compositions for blood half-life extension and contrast enhancement of diagnostic imaging.

  本发明涉及用于诊断成像的对比剂，其具有延长血液保留时间的特性。具体而言，本发明涉及新颖化合物，其特征在于具有图像增强基团（IEM）；蛋白质血浆结合基团（PPBM）；以及延长血液半衰期基团（BHEM）。本发明还涉及包括这些化合物的药物组合物，以及使用这些化合物和组合物进行血液半衰期延长和诊断成像对比增强的方法。