Sangivamycin monohydrate | 129601-63-4

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 吡咯并嘧啶核苷和核苷酸
• 英文名称: Sangivamycin monohydrate
• 英文别名: 4-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carboxamide;hydrate
• CAS: 129601-63-4
• 化学式: C12H17N5O6
• 分子量: 327.29
• InChiKey: QTYUIEDCERYPNJ-CCUUNMJDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.1
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  171
• 氢给体数：
  6
• 氢受体数：
  9

文献信息

• A METHOD FOR TESTING ANTIMICROBIAL SUSCEPTIBILITY
  申请人：The University Of Western Australia

  公开号：EP3607084A1

  公开（公告）日：2020-02-12
• COMPOSITIONS AND METHODS FOR TREATMENT OF FILOVIRUS-MEDIATED DISEASES
  申请人：Johansen Lisa M.

  公开号：US20110028564A1

  公开（公告）日：2011-02-03

  The invention features compositions, methods, and kits useful for the treatment of filovirus-mediated diseases, e.g., hemorrhagic fever caused by Ebola virus, in an animal.
• METHOD FOR TESTING ANTIMICROBIAL SUSCEPTIBILITY
  申请人：The University of Western Australia

  公开号：US20210292807A1

  公开（公告）日：2021-09-23

  The present invention relates to methods for the qualitative and quantitative determination of the susceptibility of microbial organisms such as bacteria to antimicrobial agents such as antibiotics. For example, the present invention provides a method of determining the susceptibility of a unicellular or multicellular microorganism to an antimicrobial agent by acoustic flow cytometry. The method comprising exposing cells of the microorganism to at least one antimicrobial agent, wherein said cells of the microorganism are in and/or derived from a sample obtained from a subject having or suspected of having an infection with said microorganism; measuring effect of said at least one antimicrobial agent on cellular morphology of said cells of the microorganism by acoustic flow cytometry; and determining susceptibility of the microorganism to the at least one antimicrobial agent from the acoustic flow cytometry data output.
• US8475804B2
  申请人：——

  公开号：US8475804B2

  公开（公告）日：2013-07-02
• [EN] A METHOD FOR TESTING ANTIMICROBIAL SUSCEPTIBILITY<br/>[FR] PROCÉDÉ DE TEST DE LA SENSIBILITÉ ANTIMICROBIENNE
  申请人：UNIV WESTERN AUSTRALIA

  公开号：WO2018184073A1

  公开（公告）日：2018-10-11

  The present invention relates to methods for the qualitative and quantitative determination of the susceptibility of microbial organisms such as bacteria to antimicrobial agents such as antibiotics. For example, the present invention provides a method of determining the susceptibility of a unicellular or multicellular microorganism to an antimicrobial agent by acoustic flow cytometry. The method comprising exposing cells of the microorganism to at least one antimicrobial agent, wherein said cells of the microorganism are in and/or derived from a sample obtained from a subject having or suspected of having an infection with said microorganism; measuring effect of said at least one antimicrobial agent on cellular morphology of said cells of the microorganism by acoustic flow cytometry; and determining susceptibility of the microorganism to the at least one antimicrobial agent from the acoustic flow cytometry data output.