2-(4-羟基苯甲酰基)苯甲酸 | 54996-37-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-(4-羟基苯甲酰基)苯甲酸
• 英文名称: 5-benzoylsalicylic acid
• 英文别名: 2-Hydroxy-5-benzoyl-benzoesaeure；5-benzoyl-2-hydroxy-benzoic acid；5-Benzoyl-2-hydroxy-benzoesaeure；4-Oxy-benzophenon-carbonsaeure-(3)；4-Oxy-α-oxo-diphenylmethan-carbonsaeure-(3)；4-hydroxy-3-carboxybenzophenone；5-Benzoyl-salicylsaeure；5-benzoyl-2-hydroxybenzoic acid
• CAS: 54996-37-1
• 化学式: C₁₄H₁₀O₄
• 分子量: 242.231
• InChiKey: JOKBLKCZHGIRNO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2918990090

反应信息

• 作为反应物：
  描述：

  2-(4-羟基苯甲酰基)苯甲酸 在 甲醇 、 硫酸 作用下， 生成 5-benzoyl-2-hydroxy-benzoic acid methyl ester
  参考文献：
  名称：

  Shah; Shah, Journal of the University of Bombay, Science: Physical Sciences, Mathematics, Biological Sciences and Medicine, 1949, vol. 18/3 A, p. 25,27

  摘要：

  DOI：
• 作为产物：
  描述：

  水杨酸乙酯 在 二硫化碳 、 氢氧化钾 、 三氯化铝 作用下， 生成 2-(4-羟基苯甲酰基)苯甲酸
  参考文献：
  名称：

  Limpricht, Justus Liebigs Annalen der Chemie, 1896, vol. 290, p. 168

  摘要：

  DOI：

文献信息

• [EN] DUAL ANDROGEN RECEPTOR/AKR1C3 INHIBITORS<br/>[FR] INHIBITEURS DOUBLES DE RÉCEPTEUR DES ANDROGÈNES/AKR1C3
  申请人：UNIV CALIFORNIA

  公开号：WO2021101903A1

  公开（公告）日：2021-05-27

  The present invention provides benzamide compounds, compositions containing the benzamides, and use of the benzamides for inhibiting androgen receptor (AR) and/or aldo-keto reductase family 1 member C3 (AKR1C3). Also described herein methods for the treatment of hormone-mediated diseases and conditions, including hormone-related cancers such as castration resistant prostate cancer.

  本发明提供苯甲酰胺化合物，含有苯甲酰胺的组合物，以及利用苯甲酰胺抑制雄激素受体（AR）和/或醛酮还原酶家族1成员C3（AKR1C3）的用途。本文还描述了治疗激素介导疾病和症状的方法，包括激素相关癌症，如去势耐药前列腺癌。
• Hair growth stimulant
  申请人：——

  公开号：US20030003071A1

  公开（公告）日：2003-01-02

  The present invention provides a hair growth agent and a hair fostering shampoo that have N-methyltaurine as an essential ingredient, and have hair growth period extending effects, and moreover are capable of giving hair fitness and body and giving hair a feeling of volume. Moreover, the present invention also provides a cell activating agent and a hair fitness/body improving agent that are blended into hair cosmetics.

  本发明提供了一种含有N-甲基牛磺酸作为基本成分的生发剂和促进头发生长的洗发水，它们具有延长头发生长期的效果，并且能够赋予头发健康和体积感，使头发感觉更加丰盈。此外，本发明还提供了一种细胞活化剂和一种混合在头发化妆品中的头发健康/体积改善剂。
• Fragrance composition
  申请人：TAKASAGO INTERNATIONAL CORPORATION

  公开号：US20030216283A1

  公开（公告）日：2003-11-20

  A fragrance composition having high fragrance properties such as fragrance diffusivity and long-lasting property obtained without changing the fragrance note of the fragrance composition which is useful in various fragrance providing products such as cosmetics, toiletry products, bath compositions and pharmaceuticals having satisfactory fragrance properties such as fragrance diffusivity and long-lasting property. The fragrance composition contains 0.1 to 90 % by weight of a glyceryl ether derivative represented by the following general formula (I), such as 2 -ethylhexyloxypropanediol as a fixative or fragrance note-improving agent. The fragrance providing product contains 0.01 to 50 % by weight of the fragrance composition in the final product composition. General formula (I) is: 1 wherein R 1 represents an aliphatic hydrocarbon group having 4 to 12 carbon atoms which may have a branched chain or an aromatic hydrocarbon group, which may have a substituent.

  具有高香气性能的香氛组合物，如香气扩散性和持久性，可在不改变香气组合物的香调的情况下获得，适用于各种具有满意的香气性能，如香气扩散性和持久性的化妆品、洗涤用品、沐浴组合物和药品。香气组合物包含按重量百分比为0.1到90%的由以下一般式（I）代表的甘油醚衍生物，如2-乙基己氧基丙二醇作为固定剂或香气调节剂。提供香气的产品在最终产品组合物中含有按重量百分比为0.01到50%的香气组合物。一般式（I）为：其中R1表示具有4到12个碳原子的脂肪烃基，可能具有支链或芳香烃基，可能具有取代基。
• NOVEL SUGAR DERIVATIVE GELATORS
  申请人：KYUSHU UNIVERSITY

  公开号：US20180208618A1

  公开（公告）日：2018-07-26

  A novel gelator including a sugar derivative; a gelator including a compound of Formula (1) or Formula (2): wherein R 1 is a linear or branched alkyl group having a carbon atom number of 9 to 20, a cyclic alkyl group having a carbon atom number of 13 to 20, or a linear or branched alkenyl group having a carbon atom number of 9 to 20, R 2 is a hydrogen atom, a linear or branched alkyl group having a carbon atom number of 1 to 10, or an aryl group optionally having a substituent, and R 3 and R 4 are hydroxy groups.

  一种包括糖衍生物的新型凝胶剂；一种包括化合物Formula（1）或Formula（2）的凝胶剂：其中，R1是具有碳原子数为9至20的直链或支链烷基基团，具有碳原子数为13至20的环烷基基团，或具有碳原子数为9至20的直链或支链烯基基团，R2是氢原子，具有碳原子数为1至10的直链或支链烷基基团，或具有取代基的芳基基团，而R3和R4是羟基。
• Solid Wax Composition and Solid Oily Cosmetic
  申请人：The Nisshin OilliO Group, Ltd.

  公开号：US20190307672A1

  公开（公告）日：2019-10-10

  The present invention provides a composition that has an excellent hardness adjustment action, can be used as a solidifying agent for various cosmetics, and when added to cosmetics, can impart those cosmetics with excellent shape retention properties, an oil oozing suppression effect during use, a favorable texture and good storage stability, and also provides an oily solid cosmetic to which the composition has been added. Specifically, the invention provides a solid wax composition containing a component (A):candelilla wax, and a component (B): a monoester having a total of 40 to 48 carbon atoms, wherein the mass ratio between the component (A) and the component (B) in the solid wax composition satisfies component (A):component (B)=45:55 to 95:5, and the monoester is a monoester of a monovalent fatty acid and a monohydric alcohol.

  本发明提供了一种具有优异硬度调节作用的组合物，可用作各种化妆品的固化剂，并且当添加到化妆品中时，可以赋予这些化妆品优秀的保持形状性能、使用过程中的抑制油分泌效果、良好的质地和良好的储存稳定性，并且提供了添加了该组合物的油性固体化妆品。具体来说，该发明提供了一种固体蜡组合物，包含组分（A）：蜡燭树蜡，以及组分（B）：总碳原子数为40至48的单酯，其中在固体蜡组合物中，组分（A）和组分（B）之间的质量比满足组分（A）：组分（B）=45:55至95:5，而且该单酯是一种单价脂肪酸和一价醇的单酯。