1-(1-oxo-2-propenyl)azetidine | 98501-45-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1-(1-oxo-2-propenyl)azetidine
• 英文别名: 1-(Azetidin-1-yl)prop-2-en-1-one
• CAS: 98501-45-2
• 化学式: C₆H₉NO
• mdl: MFCD12091259
• 分子量: 111.144
• InChiKey: FQCJGOFQLJELIV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  杂氮环丁烷 、 丙烯酰氯 在 三乙胺 作用下， 以 乙醚 为溶剂， 以48%的产率得到1-(1-oxo-2-propenyl)azetidine
  参考文献：
  名称：

  Living Anionic Polymerization of N-Methacryloylazetidine: Anionic Polymerizability of N,N-Dialkylmethacrylamides

  摘要：

  Anionic polymerization of a series of N, N-dialkylmethacrylamides Such as N-methacryloylazetidine (M4), N-methacryloylpyrrolidine (M5), and N-methacryloylpiperidine (M6) was carried out with diphenylmethyllithium (Ph2CHLi) or diphenylmethylpotassium (Ph2CHK) in the presence of LiCl or Et2Zn in THF to clarify the relationship between polymerizability and monomer structure. Poly(M4)s possessing predicted Molecular weights and very narrow molecular weight distributions (M-w/M-n < 1.1) were obtained quantitatively with Ph2CHLi/LiCl or Ph2CHK/Et2Zn at -40 to 0 degrees C within 24 h. From the polymerizations of M4 at the various temperatures ranging from -40 to -20 degrees C, the apparent rate constant and the activation energy of the anionic polymerization were determined as follows: In k(p)(ap) = -6.17 x 10(3)/T + 22.4 L mol(-1) s(-1) and 51 +/- 5 kJ mol(-1), respectively. Compared to the previous report oil the anionic polymerization of N-methacryloyl-2-methylaziridine (M3), the polymerization rate of M4 was significantly slower and the activation energy was slightly larger, indicating the lower polymerizability of M4. The acryloyl counterpart, N-acryloylazetidine (A4), also underwent the anionic polymerization to afford the well-defined polymer quantitatively. The polymerizations of M5 gave the polymers in 30-77% yields but did not complete even after I week at 0 degrees C. By contrast, no polymer was obtained from the anionic polymerization system of M6 similar to the case of N,N-dimethylmethacrylamide (DMMA). From the experimental results, it was demonstrated that the polymerizability of a series of N,N-dialkylmethacrylamides with cyclic substituents decreased drastically with increasing the ring size from three to six (M3 > M4 > M5 >> M6 = DMMA). The observed relative 3 polymerizability was well correlated with the chemical shifts of vinyl beta-carbons for monomers in the C-13 NMR spectra. The NMR data Suggested that the polymerizable M3 and M4 attained effective conjugation between C=C and C=O double bonds, while M5, M6, and DMMA had negligible conjugation effects.

  DOI：

  10.1021/ma901984d

文献信息

• Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain
  申请人：Barth Martine

  公开号：US20060178360A1

  公开（公告）日：2006-08-10

  The present invention concerns novel benzenesulphonamide compounds, defined by formula I and the description, their method of preparation and their use in therapy.

  本发明涉及新型苯磺酰胺化合物，由公式I和描述所定义，其制备方法及在治疗中的用途。
• POLISHING COMPOSITION
  申请人：Fujimi Incorporated

  公开号：EP3605588A1

  公开（公告）日：2020-02-05

  Provided is a polishing composition by which the amount of edge roll off can be effectively reduced. The polishing composition provided by the present invention contains an abrasive, a basic compound, a nitrogen-containing water-soluble polymer and water. The nitrogen-containing water-soluble polymer does not have a N-H bond in the molecule.

  本发明提供了一种抛光组合物，通过它可以有效地减少边缘滚落量。本发明提供的抛光组合物包含一种研磨剂、一种碱性化合物、一种含氮水溶性聚合物和水。含氮水溶性聚合物分子中没有 N-H 键。
• Method of manufacturing a heat-shrink elastomeric element
  申请人：Halliburton Energy Services, Inc.

  公开号：US11065807B2

  公开（公告）日：2021-07-20

  Provided are methods and systems for manufacturing and using heat-shrink elastomeric. An example method of manufacturing a heat-shrink elastomeric element comprises providing a thermoplastic elastomeric element having a first shape; modifying the thermoplastic elastomeric element to produce a thermoset elastomeric element having the first shape; heating the thermoset elastomeric element to a temperature of at least the glass transition temperature of the thermoset elastomeric element; adjusting the first shape of the thermoset elastomeric element to produce a second shape with at least one dimension greater than that of the first shape; and cooling the thermoset elastomeric element to a temperature below that of the glass transition temperature of the thermoset elastomeric element to produce the heat-shrink elastomeric element.

  本发明提供了制造和使用热缩弹性体的方法和系统。制造热缩弹性体元件的一种示例方法包括：提供具有第一形状的热塑性弹性体元件；对热塑性弹性体元件进行改性，以制造具有第一形状的热固性弹性体元件；将热固性弹性体元件加热到至少为热固性弹性体元件玻璃化转变温度的温度；调整热固性弹性元件的第一形状，以产生第二形状，其至少一个尺寸大于第一形状的尺寸；以及将热固性弹性元件冷却到低于热固性弹性元件玻璃化温度的温度，以产生热缩弹性元件。
• DERIVES DU BENZENESULFONAMIDE, LEUR PROCEDE DE PREPARATION ET LEUR UTILISATION POUR LE TRAITEMENT DE LA DOULEUR
  申请人：LABORATOIRES FOURNIER S.A.

  公开号：EP1606288A1

  公开（公告）日：2005-12-21
• SHAPE MEMORY POLYMERS AND PROCESS FOR PREPARING
  申请人：Georgia Tech Research Corporation

  公开号：EP2491082A1

  公开（公告）日：2012-08-29