2-(N,N-二甲氨基)-5-甲基苯酚 | 102439-20-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 中文名称: 2-(N,N-二甲氨基)-5-甲基苯酚
• 英文名称: 2-(N,N-dimethylamino)-5-methylphenol
• 英文别名: 2-(dimethylamino)-5-methylphenol；2-Dimethylamino-5-methyl-phenol
• CAS: 102439-20-3
• 化学式: C₉H₁₃NO
• 分子量: 151.208
• InChiKey: BNFWECMODLGJLC-UHFFFAOYSA-N

物化性质

• 熔点：
  75 °C(Solv: ligroine (8032-32-4))
• 沸点：
  228.5±20.0 °C(Predicted)
• 密度：
  1.063±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  23.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N,N-二甲基对甲苯胺 在 iron(III) chloride hexahydrate 、 lithium hydroxide 作用下， 以 四氢呋喃 、 水 、 甲苯 为溶剂， 反应 9.0h， 生成 2-(N,N-二甲氨基)-5-甲基苯酚
  参考文献：
  名称：

  铁 (III)-催化的 CH 官能化：N,N-二烷基苯胺的邻苯甲酰氧基化及其在 1,4-苯并恶氮中的应用

  摘要：

  介绍了通过邻位 N,N-二烷基苯胺的 C-H 官能化进行的 AC-O 键形成反应。铁催化的选择性邻苯甲酰氧基化遵循极性 Friedel-Crafts 机制，对苯胺的亲核性敏感。各种 N,N-二取代苯胺和 N-苯基杂环的苯甲酰氧基化是在极其温和的条件下进行的。此外，该方法已成功用于生成 1,4-苯并氧氮杂和 o-氨基苯酚。

  DOI：

  10.1002/ejoc.201402751

文献信息

• NOVEL 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES HAVING BOTH AROMATIC AND HALOGENIC SUBSTITUENTS
  申请人：Lori Franco

  公开号：US20140057911A1

  公开（公告）日：2014-02-27

  Certain 4,6-disubstituted aminopyrimidine derivatives having both aromatic and halogenic substituents.

  某些具有芳香族和卤素取代基的4,6-二取代氨基嘧啶衍生物。
• Postgenomic prospects of success in drug development and pharmacotherapy
  作者：A Rane

  DOI：10.1038/sj.tpj.6500013

  日期：2001.1.1
• Metal-Free Functionalization of <i>N</i>,<i>N</i>-Dialkylanilines via Temporary Oxidation to <i>N</i>,<i>N</i>-Dialkylaniline <i>N</i>-Oxides and Group Transfer
  作者：Robert S. Lewis、Michael F. Wisthoff、J. Grissmerson、William J. Chain

  DOI：10.1021/ol501813s

  日期：2014.7.18

  A simple set of protocols for the controlled elaboration of anilines is reported allowing access to a diverse array of aminophenols, aminoarylsulfonates, alkylated anilines, and aminoanilines in 29-95% yield in a single laboratory operation from easily isolable, bench-stable N,N-dialkylaniline N-oxides. The introduction of new C-O, C-C, and C-N bonds on the aromatic ring is made possible by a temporary increase in oxidation level and excision of a weak N-O bond.
• AROMATIC POLYCARBONATE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS
  申请人：KIHARA Akiko

  公开号：US20080199215A1

  公开（公告）日：2008-08-21

  In an electrophotographic photoreceptor including a conductive substrate and a single layer type photosensitive layer, the aromatic polycarbonate is contained to a single layer type photosensitive layer, which aromatic polycarbonate includes a constituent unit represented by the following general formula (1) derived from a compound having a basic asymmetric bishydroxy enamine skeleton represented by the general formula: Accordingly, the electrophotographic photoreceptor is obtained which is excellent in charge transportability, mechanical strength, electric property, durability, etc. and can form good images for a long time.
• CELLULOSE ESTER FILM FOR OPTICAL USE, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING SUCH CELLULOSE ESTER FILM FOR OPTICAL USE
  申请人：Kataoka Emiko

  公开号：US20100137578A1

  公开（公告）日：2010-06-03

  Disclosed is a cellulose ester film for optical use which contains an ultraviolet absorbent and hardly suffers from retardation fluctuations. The cellulose ester film is excellent in spectral absorption property as an optical film. In addition, the cellulose ester film is free from coloration and has excellent transparency, which having sufficient ultraviolet absorption and excellent long-term light resistance. Also disclosed are a polarizing plate and liquid crystal display wherein high contrast is maintained by using such a cellulose ester film for optical use. Specifically disclosed is a cellulose ester film for optical use which is characterized by containing at least one compound represented by one of the general formulae 1-3. Also specifically disclosed are a polarizing plate and liquid crystal display using such a cellulose ester film for optical use.