2-(N,N-二甲氨基)-5-甲基苯酚 | 102439-20-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 中文名称: 2-(N,N-二甲氨基)-5-甲基苯酚
• 英文名称: 2-(N,N-dimethylamino)-5-methylphenol
• 英文别名: 2-(dimethylamino)-5-methylphenol；2-Dimethylamino-5-methyl-phenol
• CAS: 102439-20-3
• 化学式: C₉H₁₃NO
• 分子量: 151.208
• InChiKey: BNFWECMODLGJLC-UHFFFAOYSA-N

物化性质

• 熔点：
  75 °C(Solv: ligroine (8032-32-4))
• 沸点：
  228.5±20.0 °C(Predicted)
• 密度：
  1.063±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  23.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N,N-二甲基对甲苯胺 在 iron(III) chloride hexahydrate 、 lithium hydroxide 作用下， 以 四氢呋喃 、 水 、 甲苯 为溶剂， 反应 9.0h， 生成 2-(N,N-二甲氨基)-5-甲基苯酚
  参考文献：
  名称：

  铁 (III)-催化的 CH 官能化：N,N-二烷基苯胺的邻苯甲酰氧基化及其在 1,4-苯并恶氮中的应用

  摘要：

  介绍了通过邻位 N,N-二烷基苯胺的 C-H 官能化进行的 AC-O 键形成反应。铁催化的选择性邻苯甲酰氧基化遵循极性 Friedel-Crafts 机制，对苯胺的亲核性敏感。各种 N,N-二取代苯胺和 N-苯基杂环的苯甲酰氧基化是在极其温和的条件下进行的。此外，该方法已成功用于生成 1,4-苯并氧氮杂和 o-氨基苯酚。

  DOI：

  10.1002/ejoc.201402751

文献信息

• Iron(III)-Catalyzed C-H Functionalization:<i>ortho</i>-Benzoyloxylation of<i>N</i>,<i>N</i>-Dialkylanilines and Its Application to 1,4-Benzoxazepines
  作者：Barreddi Chiranjeevi、Botla Vinayak、Thupakula Parsharamulu、Vemulapalli S. PhaniBabu、Bharatam Jagadeesh、Balasubramanian Sridhar、Malapaka Chandrasekharam

  DOI：10.1002/ejoc.201402751

  日期：2014.12

  A C–O bond-formation reaction that proceeds through C–H functionalization of N,N-dialkylanilines at the ortho-position is presented. The iron-catalyzed selective ortho-benzoyloxylation follows a polar Friedel–Crafts-like mechanism and is sensitive to the nucleophilicity of the anilines. The benzoyloxylation of a variety of N,N-disubstituted anilines and N-phenyl heterocycles is carried out under extremely

  介绍了通过邻位 N,N-二烷基苯胺的 C-H 官能化进行的 AC-O 键形成反应。铁催化的选择性邻苯甲酰氧基化遵循极性 Friedel-Crafts 机制，对苯胺的亲核性敏感。各种 N,N-二取代苯胺和 N-苯基杂环的苯甲酰氧基化是在极其温和的条件下进行的。此外，该方法已成功用于生成 1,4-苯并氧氮杂和 o-氨基苯酚。
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  申请人：Lori Franco

  公开号：US20140057911A1

  公开（公告）日：2014-02-27

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  某些具有芳香族和卤素取代基的4,6-二取代氨基嘧啶衍生物。
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  作者：A Rane

  DOI：10.1038/sj.tpj.6500013

  日期：2001.1.1
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  申请人：KIHARA Akiko

  公开号：US20080199215A1

  公开（公告）日：2008-08-21

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• CELLULOSE ESTER FILM FOR OPTICAL USE, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING SUCH CELLULOSE ESTER FILM FOR OPTICAL USE
  申请人：Kataoka Emiko

  公开号：US20100137578A1

  公开（公告）日：2010-06-03

  Disclosed is a cellulose ester film for optical use which contains an ultraviolet absorbent and hardly suffers from retardation fluctuations. The cellulose ester film is excellent in spectral absorption property as an optical film. In addition, the cellulose ester film is free from coloration and has excellent transparency, which having sufficient ultraviolet absorption and excellent long-term light resistance. Also disclosed are a polarizing plate and liquid crystal display wherein high contrast is maintained by using such a cellulose ester film for optical use. Specifically disclosed is a cellulose ester film for optical use which is characterized by containing at least one compound represented by one of the general formulae 1-3. Also specifically disclosed are a polarizing plate and liquid crystal display using such a cellulose ester film for optical use.