5-Chloro-6-methyl-N-[1-(4-methylphenyl)ethyl]pyrimidin-4-amine | 83942-38-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 5-Chloro-6-methyl-N-[1-(4-methylphenyl)ethyl]pyrimidin-4-amine
• CAS: 83942-38-5
• 化学式: C₁₄H₁₆ClN₃
• 分子量: 261.75
• InChiKey: YCDBFVLFCCFHMR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  37.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them
  申请人：SANKYO COMPANY LIMITED

  公开号：EP0057440A1

  公开（公告）日：1982-08-11

  Compounds having the formula (I) (wherein: R1 and R2 are each alkyl or halogen, or they are trimethylene or tetramethylene; R3 is hydrogen or alkyl; A is alkylene; and R4 is optionally substituted phenyloxy or benzyloxy substituted with at least one alkyl, halogen, alkoxy, alkylthio, alkenyl, trifluoromethyl or nitro; optionally substituted phenyl substituted with one or two halogen atoms, alkyl or alkoxy; furyl or thienyl) and their salts are potent fungicidal, insecticidal and acaricidal agents which may be prepared by reacting a compound of formula (IV) (wherein R' and R2 are as defined and R7 is a leaving group), with a compound of formula (V)

  具有式（I）的化合物 其中R1 和 R2 分别是烷基或卤素，或者是三亚甲基或四亚甲基；R3 是氢或烷基；A 是亚烷基；R4 是被至少一个烷基、卤素、烷氧基、烷硫基、烯基、三氟甲基或硝基取代的任选取代的苯氧基或苄氧基；被一个或两个卤素原子、烷基或烷氧基取代的任选取代苯基；呋喃基或噻吩基）及其盐类是强效的杀真菌、杀虫和杀螨剂，可通过与式 (IV) 化合物反应制得 (其中 R' 和 R2 定义相同，R7 为离去基团）与式（V）化合物反应制得
• US4435402A
  申请人：——

  公开号：US4435402A

  公开（公告）日：1984-03-06