1-(p-Nitrophenyl)-3-(p-dimethylaminophenyl)-thioharnstoff | 32767-52-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(p-Nitrophenyl)-3-(p-dimethylaminophenyl)-thioharnstoff
• 英文别名: 1-(4-(Dimethylamino)phenyl)-3-(4-nitrophenyl)-2-thiourea；1-[4-(dimethylamino)phenyl]-3-(4-nitrophenyl)thiourea
• CAS: 32767-52-5
• 化学式: C₁₅H₁₆N₄O₂S
• 分子量: 316.384
• InChiKey: ZTFJDQSUKGFENB-UHFFFAOYSA-N

物化性质

• 沸点：
  480.1±55.0 °C(Predicted)
• 密度：
  1.390±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  105
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  N,N-二甲基-对苯二胺 、 异硫代氰基4-硝基苯酯 以 四氢呋喃 为溶剂， 反应 9.0h， 以71%的产率得到1-(p-Nitrophenyl)-3-(p-dimethylaminophenyl)-thioharnstoff
  参考文献：
  名称：

  Urea-based constructs readily amplify and attenuate nonlinear optical activity in response to H-bonding and anion recognition

  摘要：

  首次证明基于尿素的分子结构在溶液中具有非线性光学（NLO）活性。我们证明自组装触发了 NLO 活性的大幅扩增和特定阴离子识别驱动的衰减。这种正交调制以及出色的非线性-透明度权衡使它们成为有吸引力的非线性光学探针，用于通过二次谐波显微镜进行弱自组装和阴离子传输相关的研究。

  DOI：

  10.1039/c2cc36631b

文献信息

• Walter,W.; Ruess,K.-P., Justus Liebigs Annalen der Chemie, 1971, vol. 746, p. 54 - 64
  作者：Walter,W.、Ruess,K.-P.

  DOI：——

  日期：——
• NOVEL COMPOUNDS
  申请人：New Pharma Research Sweden AB

  公开号：EP1224165A1

  公开（公告）日：2002-07-24
• Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems
  申请人：Utterodt Andreas

  公开号：US20070040151A1

  公开（公告）日：2007-02-22

  A two-component initiator system having accelerators for curing polymerizable materials comprising the following components: (a) a hydroperoxide compound containing one or more hydroperoxide groups that are bound to a tertiary carbon; (b) a thiourea derivative; and (c) as accelerator, a copper compound which is soluble in the preparation is preferably free of amine and is particularly suited for polymerizable dental compositions.
• US6875764B1
  申请人：——

  公开号：US6875764B1

  公开（公告）日：2005-04-05
• [EN] NOVEL COMPOUNDS<br/>[FR] NOUVEAUX COMPOSES
  申请人：NEW PHARMA RES SWEDEN AB

  公开号：WO2001030749A1

  公开（公告）日：2001-05-03

  The present invention relates to novel compounds, pharmaceutical compositions containing the same as well as a method for treatment of parasitic disorders, wherein said compounds are administered. The present compounds are especially well suited for treatment of coccidiosis, particularly in poultry, and they have general formula (I), where Y is S or O and R is as defined in the specification.