[2-[[[Diethoxy(oxido)phosphaniumyl]-(4-nitrophenyl)methyl]amino]phenyl]-phenylmethanone | 1203510-89-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [2-[[[Diethoxy(oxido)phosphaniumyl]-(4-nitrophenyl)methyl]amino]phenyl]-phenylmethanone
• 英文别名: [2-[[[diethoxy(oxido)phosphaniumyl]-(4-nitrophenyl)methyl]amino]phenyl]-phenylmethanone
• CAS: 1203510-89-7
• 化学式: C₂₄H₂₅N₂O₆P
• 分子量: 468.446
• InChiKey: YBXCBKZQHUOOLX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  33
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  116
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  对硝基苯甲醛 、 亚磷酸二乙酯 、 2-氨基二苯甲酮 在 AlKIT-5⁽¹⁰⁾ 作用下， 以 乙腈 为溶剂， 反应 5.0h， 以85%的产率得到[2-[[[Diethoxy(oxido)phosphaniumyl]-(4-nitrophenyl)methyl]amino]phenyl]-phenylmethanone
  参考文献：
  名称：

  Mesoporous aluminosilicate nanocage-catalyzed three-component coupling reaction: an expedient synthesis of α-aminophosphonates

  摘要：

  Here we demonstrate for the first time the synthesis of alpha-aminophosphonates through the three-component coupling reaction of aldehydes, amines, and diethyl phosphite by using highly acidic 3D mesoporous aluminosilicate nanocage catalyst, which gave excellent yield with a high selectivity in a short reaction time due to its high acidity, 3D pores, and a huge space in the nanocages. (c) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.10.003

文献信息

• Mesoporous aluminosilicate nanocage-catalyzed three-component coupling reaction: an expedient synthesis of α-aminophosphonates
  作者：Ajayan Vinu、Pranjal Kalita、Veerappan V. Balasubramanian、Hamid Oveisi、Tamil Selvan、Ajayan Mano、Murugulla A. Chari、B.V. Subba Reddy

  DOI：10.1016/j.tetlet.2009.10.003

  日期：2009.12

  Here we demonstrate for the first time the synthesis of alpha-aminophosphonates through the three-component coupling reaction of aldehydes, amines, and diethyl phosphite by using highly acidic 3D mesoporous aluminosilicate nanocage catalyst, which gave excellent yield with a high selectivity in a short reaction time due to its high acidity, 3D pores, and a huge space in the nanocages. (c) 2009 Elsevier Ltd. All rights reserved.