N,N'-(1,3-phenylene)bis(4-fluorobenzamide) | 142629-47-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N'-(1,3-phenylene)bis(4-fluorobenzamide)
• 英文别名: 4-fluoro-N-[3-[(4-fluorobenzoyl)amino]phenyl]benzamide
• CAS: 142629-47-8
• 化学式: C₂₀H₁₄F₂N₂O₂
• 分子量: 352.34
• InChiKey: UMFCDXRRLQDGTB-UHFFFAOYSA-N

物化性质

• 熔点：
  265-267 °C(Solv: N,N-dimethylformamide (68-12-2); water (7732-18-5))
• 沸点：
  378.0±37.0 °C(Predicted)
• 密度：
  1.378±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  26
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N,N'-(1,3-phenylene)bis(4-fluorobenzamide) 在 N-benzyl-DABCO tribromide 、 劳森试剂 作用下， 以 四氯化碳 、 二氯甲烷 、 甲苯 为溶剂， 反应 1.0h， 生成
  参考文献：
  名称：

  Mild and Convenient Synthesis of Benzodithiazoles by Oxidative Cyclization of Bis(thiobenzanilides)

  摘要：

  Benzodithiazoles were prepared by oxidative cyclization of bis(thiobenzanilides). The reactions were performed at room temperature under mild conditions and rely on the use of N-benzyl-DABCO tribromide.

  DOI：

  10.1055/s-0032-1317510
• 作为产物：
  描述：

  对氟苯甲酰氯 、 间苯二胺 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 生成 N,N'-(1,3-phenylene)bis(4-fluorobenzamide)
  参考文献：
  名称：

  Mild and Convenient Synthesis of Benzodithiazoles by Oxidative Cyclization of Bis(thiobenzanilides)

  摘要：

  Benzodithiazoles were prepared by oxidative cyclization of bis(thiobenzanilides). The reactions were performed at room temperature under mild conditions and rely on the use of N-benzyl-DABCO tribromide.

  DOI：

  10.1055/s-0032-1317510

文献信息

• THERMALLY REVERSIBLE CROSS-LINKED POLY (ARYL ETHER KETONE) MEDIA AND METHOD FOR HIGH DENSITY DATA STORAGE
  申请人：DiPietro Richard Anthony

  公开号：US20080186612A1

  公开（公告）日：2008-08-07

  A composition of matter for a recording medium in atomic force data storage devices. The composition includes one or more poly(aryl ether ketone) copolymers, each of the one or more poly(aryl ether ketone) copolymers including (a) a first monomer including an aryl ether ketone and (b) a second monomer including an aryl ether ketone and a hydrogen bonding cross-linking moiety, the moiety capable of forming two or more hydrogen bonds at room temperature, each of the one or more poly(aryl ether ketone) copolymers having two terminal ends, each terminal end having a phenylethynyl moiety. The covalent and hydrogen bonding cross-linking of the poly(aryl ether ketone) oligomers may be tuned to match thermal and force parameters required in read-write-erase cycles.

  一种用于原子力数据存储设备中的记录介质的物质组成物。该组成物包括一种或多种聚芳醚酮共聚物，每种聚芳醚酮共聚物包括（a）第一单体，包括芳基醚酮和（b）第二单体，包括芳基醚酮和氢键交联基团，该基团能够在室温下形成两个或更多的氢键，每种聚芳醚酮共聚物具有两个端点，每个端点具有苯乙炔基团。聚芳醚酮寡聚物的共价和氢键交联可以调节以匹配读写擦除循环所需的热和力参数。
• THERMALLY REVERSIBLE CROSS-LINKED POLY(ARYL ETHER KETONE) MEDIA AND METHOD FOR HIGH DENSITY DATA STORAGE
  申请人：DiPietro Richard Anthony

  公开号：US20110257344A1

  公开（公告）日：2011-10-20

  A composition of matter for a recording medium in atomic force data storage devices. The composition includes one or more poly(aryl ether ketone) copolymers, each of the one or more poly(aryl ether ketone) copolymers including (a) a first monomer including an aryl ether ketone and (b) a second monomer including an aryl ether ketone and a hydrogen bonding cross-linking moiety, the moiety capable of forming two or more hydrogen bonds at room temperature, each of the one or more poly(aryl ether ketone) copolymers having two terminal ends, each terminal end having a phenylethynyl moiety. The covalent and hydrogen bonding cross-linking of the poly(aryl ether ketone) oligomers may be tuned to match thermal and force parameters required in read-write-erase cycles.

  一种用于原子力数据存储设备中的记录介质的物质组成物。该组成物包括一个或多个聚芳醚酮共聚物，每个聚芳醚酮共聚物包括（a）第一单体，其中包括芳基醚酮和（b）第二单体，其中包括芳基醚酮和氢键交联基团，该基团能够在室温下形成两个或更多的氢键，每个聚芳醚酮共聚物具有两个端点，每个端点具有苯乙炔基团。聚芳醚酮寡聚物的共价和氢键交联可以调整以匹配读写擦除循环所需的热力学和力学参数。
• A journey from benzanilides to dithiobenzanilides: Synthesis of selective spasmolytic compounds
  作者：Gerda Brunhofer、Walter H. Granig、Christian R. Studenik、Thomas Erker

  DOI：10.1016/j.bmc.2010.11.043

  日期：2011.1

  A series of dithiobenzanilide derivatives was synthesized and each compound was evaluated for its ability to reduce KCl-induced contractions of smooth muscle preparations of the guinea pig. Starting from a recent publication describing benzanilide derivatives as antispasmodic agents, structure-activity guided synthesis was performed to obtain compounds with improved spasmolytic activity. First, compounds with two amide bonds were designed and second, both amide oxygens were replaced by two sp(2) sulfur atoms resulting in dithiobenzanilide derivatives. The most potent antispasmodic dithiobenzanilide 19 showed improved activity with an IC50 value of 0.4 mu M. Moreover, the study also demonstrated that these active compounds were able to antagonize the effect of spasmogens like acetylcholine and phenylephrine and that the activity is not mediated by activation of ATP-dependent potassium channels (K-ATP-channels) or inhibition of endothelial nitric oxide synthase (eNOS). (C) 2010 Elsevier Ltd. All rights reserved.
• CHLORINE RESISTANT POLYAMIDES AND MEMBRANES MADE FROM THE SAME
  申请人：Murphy Andrew Patrick

  公开号：US20080277333A1

  公开（公告）日：2008-11-13

  A chlorine resistant polyamide is formed from the reaction product of an amine and an acid chloride monomer wherein the acid chloride monomer is modified with electron-withdrawing groups that exhibit sufficient activity to (i) minimize any chlorination on both the amine and acid chloride side and (ii) minimize N-chlorination. A membrane is made from the polyamide and, in one application, the membrane is used in a desalination unit.
• METHOD FOR FORMING AND ALIGNING CHEMICALLY MEDIATED DISPERSION OF MAGNETIC NANOPARTICLES IN A POLYMER
  申请人：Hedrick James Lupton

  公开号：US20090184445A1

  公开（公告）日：2009-07-23

  A method. The method includes providing Au-doped Co nanoparticles. The nanoparticles include a combination of non-ferromagnetic nanoparticles and weakly ferromagnetic nanoparticles. The nanoparticles each have an exterior surface. The surfaces of the nanoparticles are functionalized with 7-(5-uracil-ylcarbamoyl)heptanoic acid. A polymer is provided having a general formula including a uracil group. A dispersion is formed by agitating a solution of the nanoparticles. The solution is spin cast into a film. The film is heated under vacuum at a first temperature, T FM , resulting in inducing ferromagnetism in the non-ferromagnetic nanoparticles and converting the non-ferromagnetic nanoparticles to ferromagnetic nanoparticles, and resulting in enhancing ferromagnetism in the weakly ferromagnetic nanoparticles. The nanoparticles are aligned such that magnetic easy axes of the nanoparticles are oriented by applying a magnetic field to the dispersion while at a second temperature less than T FM . The axes align in a plane parallel to a plane of the film.