benzimidazolium bromide | 856635-57-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: benzimidazolium bromide
• 英文别名: benzimidazole*HBr；1H-benzimidazol-3-ium;bromide
• CAS: 856635-57-9
• 化学式: BrH*C₇H₆N₂
• 分子量: 199.05
• InChiKey: IAPYEHYJJVRSFB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.14
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  28.7
• 氢给体数：
  2
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  hydrogen tetrabromopalladate (II) 、 benzimidazolium bromide 以 乙醇 、 水 为溶剂， 生成
  参考文献：
  名称：

  Kukushkin, Yu. N.; Sedova, G. N.; Pyzhova, L. Ya., Russian Journal of Inorganic Chemistry, 1979, vol. 24, p. 1257 - 1258

  摘要：

  DOI：
• 作为产物：
  描述：

  2,2-Dibromo-3-oxo-3-phenyl-propionaldehyde 在 邻苯二胺 作用下， 以 四氯化碳 为溶剂， 以28%的产率得到2,2-二溴-1-苯乙酮
  参考文献：
  名称：

  Reaction of α-halo- and α,α-dihalo-β-oxoaldehydes witho- andm-phenylenediamines

  摘要：

  alpha-Halo-beta-oxoaldehydes react with o- and m-phenylenediamines to give alpha-halo-beta-oxoenamines. In the case of o-phenylenediamine, the initially formed monoenamine undergoes concurrent intramolecular cyclization to give benzimidazole and a halocarbonyl compound. alpha,alpha-Dihalo-beta-oxoaldehydes react with o- and m-phenylenediamines according to the haloformic decomposition scheme involving formylation of amino groups.

  DOI：

  10.1007/bf02495653

文献信息

• SELF-REGENERATING ANTIOXIDANT CATALYSTS AND METHODS OF USING THE SAME
  申请人：Clemson University

  公开号：US20160151773A1

  公开（公告）日：2016-06-02

  The present invention relates to self-regenerating antioxidant catalysts and methods of using the same.

  本发明涉及自再生抗氧化剂催化剂及其使用方法。
• Methods of Forming Carbene-Functionalized Composite Materials
  申请人：Queen's University at Kingston

  公开号：US20190169132A1

  公开（公告）日：2019-06-06

  Deposition of carbene monolayers that excluded starting anions, such as iodide ions, has been achieved. Anions such as iodide are a typical contaminant in carbene hydrogen carbonate salts when synthesized using the state-of-the-art method. A method is described for eliminating substantially all starting anion (e.g., iodide) contamination from the monolayer. Air stable, purified carbenes precursors were used to deposit an intact monolayer on the surface of some industrially relevant metals. The monolayer's ability to protect these metals against, for example, oxidation has been demonstrated.

  已经实现了排除起始阴离子（如碘离子）的卡宾单分子沉积。当使用最先进的方法合成卡宾氢碳酸盐时，碘离子等阴离子是典型的污染物。描述了一种方法，用于从单分子中消除几乎所有起始阴离子（例如碘）的污染。使用空气稳定、纯化的卡宾前体沉积在一些工业相关金属表面上形成完整的单分子层。已经证明了这种单分子层保护这些金属免受氧化等影响的能力。
• [EN] ANTIVIRAL COMPOUNDS<br/>[FR] COMPOSÉS ANTIVIRAUX
  申请人：LUPIN LTD

  公开号：WO2013030750A1

  公开（公告）日：2013-03-07

  Compounds of the general formula (I), their tautomeric forms, their stereoisomers, their analogs, their prodrugs, their isotopes, their N-oxides, their metabolites, their pharmaceutically acceptable salts, polymorphs, solvates, optical isomers, clathrates, co-crystals, combinations with suitable medicament, pharmaceutical compositions containing them, methods of making of the above compounds, and their use as antiviral candidate, more specifically as anti-HCV are disclosed.

  本发明公开了一般式（I）的化合物，它们的互变异构体，立体异构体，类似物，前药，同位素，N-氧化物，代谢物，药学上可接受的盐，多晶体，溶剂合物，光学异构体，笼合物，与适当药物的组合，含有它们的制药组合物，上述化合物的制备方法，以及它们作为抗病毒候选物，更具体地作为抗HCV的用途。
• BENZIMIDAZOLES AND ANALOGS AS RHO KINASE INHIBITORS
  申请人：Feng Yangbo

  公开号：US20110052562A1

  公开（公告）日：2011-03-03

  Compounds useful as Rho kinase inhibitors according to formula IA or IB: wherein A, B, D, E, R 1 , R 2 and Ar 1 are as defined herein, and any tautomer, salt, stereoisomer, hydrate, solvent, or prodrug thereof, pharmaceutical compositions, methods of treatment, and synthetic methods are provided.

  提供公式IA或IB所示的有用的Rho激酶抑制剂化合物：其中A、B、D、E、R1、R2和Ar1的定义如本文所述，并提供任何互变异构体、盐、立体异构体、水合物、溶剂或前药，以及制药组合物、治疗方法和合成方法。
• Controllable Synthesis of Centimeter-Sized 2D Ruddlesden–Popper Perovskite Single Crystals through Intermediate-Phase Engineering
  作者：Xijuan Sun、Mengling Xia、Mingquan Liao、Jiaqi Liu、Ping Lu、Yinsheng Xu、Guangda Niu、Xianghua Zhang

  DOI：10.1021/acs.cgd.3c00093

  日期：2023.5.3

  benzimidazole) perovskite single crystals by intermediate-phase engineering (IPE). 1D (DMF)2BMPbBr3 intermediate-phase single crystals were structurally decoupled and transformed to perfect 2D BM2PbBr4 seed crystals with a certain thickness, presenting a huge advantage over the extrathin crystal sheets in random stacking by natural crystallization. Furthermore, the new BM with conjugated structures we obtained

  二维 Ruddlesden–Popper (RP) 钙钛矿已展示出高性能发射体，大尺寸钙钛矿单晶一直是高效光电器件的追求。然而，由于层间相互作用弱、各向异性强，大尺寸、高质量的二维RP钙钛矿单晶仍然难以获得。在这里，我们展示了一种通过中间相工程 (IPE) 合成厘米级 2D BM 2 PbBr 4（BM = 苯并咪唑）钙钛矿单晶的合理设计策略。一维 (DMF) 2 BMPbBr 3中间相单晶在结构上解耦并转化为完美的二维 BM 2 PbBr 4具有一定厚度的晶种，在自然结晶的随机堆叠方面比超薄晶体片具有巨大的优势。此外，我们作为 2D RP 钙钛矿的 A 位点获得的具有共轭结构的新 BM 增强了激子限制，导致激子结合能达到惊人的 368.2 meV。发射衰减时间缩短至0.98 ns，是所有钙钛矿材料中最小的。为 2D RP BM 2 PbBr 4 –  x Cl x ( x= 1、2、3 和