3-methylphenyl phenylcarbamate | 15341-57-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-methylphenyl phenylcarbamate
• 英文别名: phenyl-carbamic acid-[2]naphthyl ester；Phenyl-carbamidsaeure-[2]naphthylester；Carbanilsaeure-β-naphthylester；naphthalen-2-yl N-phenylcarbamate
• CAS: 15341-57-8
• 化学式: C₁₇H₁₃NO₂
• 分子量: 263.296
• InChiKey: CQZFJFILBMLBSV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2924299090

反应信息

• 作为反应物：
  描述：

  3-methylphenyl phenylcarbamate 在 三氯化铝 、 xylene 作用下， 生成 2-羟基-N-苯基萘-1-甲酰胺
  参考文献：
  名称：

  Gerschson, Zhurnal Obshchei Khimii, 1943, vol. 13, p. 68,75

  摘要：

  DOI：
• 作为产物：
  描述：

  异氰酸苯酯 、 2-萘酚 生成 3-methylphenyl phenylcarbamate
  参考文献：
  名称：

  Snape, Chemische Berichte, 1885, vol. 18, p. 2430

  摘要：

  DOI：

文献信息

• A Fe₃ O₄ @SiO₂ /Schiff Base/Pd Complex as an Efficient Heterogeneous and Recyclable Nanocatalyst for One-Pot Domino Synthesis of Carbamates and Unsymmetrical Ureas
  作者：Iman Dindarloo Inaloo、Sahar Majnooni

  DOI：10.1002/ejoc.201901140

  日期：2019.10.9

  A palladium‐catalyzed domino method for the direct synthesis of carbamates and ureas has been developed by using readily available and economical starting materials (aryl halide, carbon monoxide, sodium azide, amines, and alcohols) in a one‐pot approach. This efficient and phosgene‐free process provided an inexpensive and attractive route to synthesize the products in good to excellent yields.

  通过一锅法使用容易获得且经济的起始原料（芳基卤化物，一氧化碳，叠氮化钠，胺和醇），已经开发了直接催化氨基甲酸酯和脲合成钯催化的多米诺骨牌方法。这种高效且无光气的工艺提供了一种廉价且诱人的途径，可以以良好的收率获得优良的合成产物。
• INHIBITORS OF FATTY ACID AMIDE HYDROLASE
  申请人：Dasse Olivier

  公开号：US20070155747A1

  公开（公告）日：2007-07-05

  Pharmacological inhibition of fatty acid amide hydrolase (FAAH) activity leads to increased levels of fatty acid amides. Esters of alkylcarbamic acids are disclosed that are inhibitors of FAAH activity. Compounds disclosed herein inhibit FAAH activity. Described herein are processes for the preparation of esters of alkylcarbamic acid compounds, compositions that include them, and methods of use thereof.

  药物抑制脂肪酸酰胺水解酶（FAAH）活性会导致脂肪酸酰胺水平的增加。本文披露了烷基氨基酸酯类化合物，其可作为FAAH活性抑制剂。本文披露的化合物可抑制FAAH活性。本文还描述了制备烷基氨基酸酯类化合物的方法、包括它们的组合物以及使用它们的方法。
• Carbamate derivatives, process for producing the same and herbicides comprising the compounds as an effective component
  申请人：TOSOH CORPORATION

  公开号：EP0090263A1

  公开（公告）日：1983-10-05

  Carbamate derivatives represented by the general formula (I): wherein X represents an oxygen atom or a sulfur atom and Y represents CH group or a nitrogen atom; a process for producing the same; and herbicides employing the same.

  由通式(I)代表的氨基甲酸酯衍生物： 其中 X 代表氧原子或硫原子，Y 代表 CH 基团或氮原子。
• EFFICACY, SAFETY AND PATIENT SATISFACTION OUTCOMES OF THE AMS 700CX INFLATABLE PENILE PROSTHESIS: RESULTS OF A LONG-TERM MULTICENTER STUDY
  作者：CULLEY C. CARSON、JOHN J. MULCAHY、FRED E. GOVIER

  DOI：10.1016/s0022-5347(05)67364-8

  日期：2000.8

  Purpose: We performed a long-term multicenter study of the AMS 700CX double dagger 3-piece inflatable penile prosthesis, focusing on longevity, morbidity and patient satisfaction in men implanted up to 134 months with a median followup of 47.7 months.Materials and Methods: We performed a large scale retrospective multicenter study in 2 phases. Phase 1 was a medical record review of 372 men who underwent implantation with the AMS 700CX penile prosthesis from 1987 to 1996 by 7 frequent penile prosthesis implanters, Phase 2 included a structured telephone interview of 207 patients by a neutral observer.Results: For the 372 men in phase 1 mean device mechanical reliability plus or minus standard deviation was 92.1% +/- 3.3% affer 3 and 86.2% +/- 4.6% after 5 years. Patient age was 21 to 79 years (mean 57.6 +/- 11.0) at implantation. The etiology of erectile dysfunction was vascular in 27.7% of the cases, Peyronie's disease in 16.9%, diabetes mellitus in 12.9% and radical surgery in 11.6%. Of the men 55.6% received previous treatment for erectile dysfunction. Postoperative infection and device malfunction developed in 3.2% and 17.5% of the cases, respectively. Of the 207 men interviewed in phase 2, 86% still had an AMS 700CX penile prosthesis implanted, including 87.1% with erection suitable for coitus. Currently 79% of those with a device use it at least twice monthly and 88.2% would recommend an implant to a relative or friend.Conclusions: The AMS 700CX penile implant produced suitable erection and excellent patient satisfaction at long-term followup in the majority of men. Implant reliability is excellent and postoperative morbidity is low.
• Leuckart; Schmidt,M., Chemische Berichte, 1885, vol. 18, p. 2340
  作者：Leuckart、Schmidt,M.

  DOI：——

  日期：——

表征谱图