silver mesitylate | 51750-69-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: silver mesitylate
• 英文别名: 2,4,6-trimethyl-benzoic acid ; silver-salt；2,4,6-Trimethyl-benzoesaeure; Silber-Salz；Silber-2,4,6-trimethyl-benzoat；Silver;2,4,6-trimethylbenzoate
• CAS: 51750-69-7
• 化学式: Ag*C₁₀H₁₁O₂
• 分子量: 271.064
• InChiKey: VIANXKHMNYCWON-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.97
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  40.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  二苯基锑二氯化物 、 silver mesitylate 在 H₂O 作用下， 以 甲苯 为溶剂， 以65%的产率得到[SbPh2(O2CC6H2Me3-2,4,6)2]2O
  参考文献：
  名称：

  Diphenylantimony(V) oxo/chloro carboxylates and phosphinates: crystal structures of {SbPh2Cl[O2P(C6H11)2]}2O and [SbPh2(O2CPh)2]2O

  摘要：

  Reaction of SbPh(2)Cl(3) (1 mol) with the silver salt of dicyclohexylphosphinic acid (2 mol) afforded {SbPh(2)Cl[O2P(C6H11)(2)]}O-2 1, a similar reaction with AgO2P(C8H15)(2) gave a product formulated as {SbPh(2)Cl[O2P(C8H15)(2)]}O-2 2. Similar reactions with silver carboxylates (1:3 stoichiometry) led to the crystalline derivatives [SbPh(2)(O(2)CR)(2)]O-2 (R = Ph 3, CHPh(2) 4, 2,4,6-Me(3)C(6)H(2) 5, 2-MeC(6)H(4) 6 or 4-MeC(6)H(4) 7), whereas the 1:2 reaction afforded crystalline SbPh(2)Cl(O(2)CR)(2) (R = Ph 8, 2-MeC(6)H(4) 9 or 4-MeC(6)H(4) 10). Interconversion of the previously known compounds [SbPh(2)(O(2)CMe)(2)]O and Sb(4)Ph(8)O(6) . 3MeCO(2)H was achieved and established by H-1 NMR spectroscopy. Compounds 1 and 3 were further characterized by X-ray diffraction; the antimony in 1 is six-co-ordinated with bridging phosphinates whereas in 3 it is seven-co-ordinated with chelating benzoates. Short Sb-O (oxo) distances (1.923 Angstrom) and near linearity at the bridging oxygen (Sb-O-Sb 173.9 degrees) are observed for 3.

  DOI：

  10.1039/dt9950002151
• 作为产物：
  描述：

  2,4,6-三甲基苯甲酸 、 silver nitrate 在 NH₃ 作用下， 以 水 为溶剂， 以96%的产率得到silver mesitylate
  参考文献：
  名称：

  Aerosol-assisted chemical vapour deposition (AACVD) of silver films from triorganophosphine adducts of silver carboxylates, including the structure of [Ag(O2CC3F7)(PPh3)2]

  摘要：

  Silver carboxylates [Ag(O2CR): R = Me, Bu-t, 2,4,6-Me3C6H2], fluorocarboxlyates [Ag(O2CRf): R-f = C3F7, C6F13, C7F15] and their phosphine adducts [Ag(O2CR).nPR(3)': R = Me, Bu-t, 2,4,6-Me3C6H2, R' = Me, Ph, n = 2; R = Me, R' = Me, n = 3; Ag(O2CRf).2PPh(3), R-f = C3F7, C6F13, C7F15] have been synthesised, characterised spectroscopically and used as precursors in the aerosol-assisted chemical vapour deposition of silver films. All the phosphine adducts produced films, though in general PMe3 adducts, proved more successful than PPh3 analogues. The fluoro-carboxylates and their PPh3 adducts all generated silver film, though the growth rate for the adducts was lower. All these latter films showed carbon impurities while fluorine was also evident in most cases. The X-ray structure of AgO2CC3F7.2PPh(3) is also reported. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0020-1693(01)00718-6

文献信息

• 4-SUBSTITUTED CEPHEM DERIVATIVES AS ELASTASE INHIBITORS
  申请人：——

  公开号：US20010011085A1

  公开（公告）日：2001-08-02

  The present invention relates to cephem-derivatives and to a process for their preparation, having proper substituents at C-2 position, i.e. heterocyclylthio or acyloxy group. They are potent protease inhibitors, in particular human leucocyte elastase (HLE) inhibitors. These inhibitors can be synthesised by way of a substitution reaction starting from known cephem compounds having a 2-position a suitable leaving group.

  本发明涉及头孢烯衍生物及其制备方法，该衍生物在C-2位具有适当的取代基，即杂环硫基或酰氧基。它们是强效的蛋白酶抑制剂，特别是人白细胞弹性蛋白酶（HLE）抑制剂。这些抑制剂可以通过从已知的头孢烯化合物开始，通过取代反应合成，该化合物在2位具有合适的离去基团。
• IRIDIUM-DIPHOSPHINE COMPLEXES AND PROCESS FOR THE HYDROGENATION OF IMINES
  申请人：Novartis AG

  公开号：EP0850241B1

  公开（公告）日：2001-08-29
• US6008393A
  申请人：——

  公开号：US6008393A

  公开（公告）日：1999-12-28
• [EN] IRIDIUM-DIPHOSPHINE COMPLEXES AND PROCESS FOR THE HYDROGENATION OF IMINES<br/>[FR] COMPLEXES D'IRIDIUM-DIPHOSPHINE ET PROCEDE D'HYDROGENATION DES IMINES
  申请人：NOVARTIS AG

  公开号：WO1997005150A1

  公开（公告）日：1997-02-13

  (EN) Compounds of formulae I: (DIP)IrXqYr(Z), Ia: (DIP)IrXsYt(Z)2 and Ib: (DIP)Ir(Z)3 or mixtures of at least two of those compounds, wherein DIP is a ditertiary diphosphine, the two phosphine groups of which are bonded to a C2-, C3- or C4-carbon chain, with the result that the diphosphine forms a 5- to 7-membered ring together with the Ir atom, X is Cl, Br or I, Y is a hydrogen atom, q and r are 0, 1 or 2 and the sum of q+r is 2, s and t are 0 or 1 and the sum of s+t is 1, and Z is the anion of an organic oxy acid that contains a group C(=O)O, S(=O)O or P(=O)O in the anion. The compounds are excellent catalysts for the hydrogenation of imines, especially for the enantioselective hydrogenation of prochiral imines.(FR) L'invention porte sur les composés de formules (I): (DIP)IrXqYr(Z), (Ia): (DIP)IrXsYt(Z)2 et (Ib): (DIP)Ir(Z)3 ou des mélanges d'au moins deux d'entre eux. Dans ces formules: DIP est une diphosphine ditertiaire dont deux des groupes phosphine sont liés à une chaîne carbonée C2, C3 ou C4 d'où résulte que la diphosphine constitue, avec l'atome d'Ir, un cycle à 5 à 7 éléments, X est Cl, Br ou I, Y est H, q et r sont 0, 1 ou 2 et la somme de q + r est 2, s et t sont 0 ou 1 et la somme de s+t est 1, et Z est l'anion d'un oxyacide, ledit anion comportant un groupe C(=O),S(=O)O ou P(=O)O. Ces composés sont d'excellents catalyseurs pour l'hydrogénation des imines, et notamment pour l'hydrogénation énantiosélective des imines prochirales.