2,4,6-trimethyl-benzoic acid-(2-diethylamino-ethyl ester) | 108983-07-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,4,6-trimethyl-benzoic acid-(2-diethylamino-ethyl ester)
• 英文别名: 2,4,6-Trimethyl-benzoesaeure-(2-diaethylamino-aethylester)；2,4,6-Trimethyl-benzoesaeure-(2-diethylamino-ethylester)；Benzoic acid, 2,4,6-trimethyl-, 2-(diethylamino)ethyl ester；2-(diethylamino)ethyl 2,4,6-trimethylbenzoate
• CAS: 108983-07-9
• 化学式: C₁₆H₂₅NO₂
• 分子量: 263.38
• InChiKey: VZVHWWWJZRQAOW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2,4,6-三甲基苯甲酸 在 potassium carbonate 、 甲苯 作用下， 生成 2,4,6-trimethyl-benzoic acid-(2-diethylamino-ethyl ester)
  参考文献：
  名称：

  β-DIETHYLAMINOETHYL ESTERS OF STERICALLY HINDERED ALKYL SUBSTITUTED BENZOIC ACIDS

  摘要：

  DOI：

  10.1021/jo01120a019

文献信息

• Hach et al., Collection of Czechoslovak Chemical Communications, 1957, vol. 22, p. 1887,1891
  作者：Hach et al.

  DOI：——

  日期：——
• Anesthetic Compounds
  申请人：Jenkins Thomas E.

  公开号：US20100056575A1

  公开（公告）日：2010-03-04

  In one embodiment the invention provides novel compounds of Formula (I) as well as prodrugs, salts, hydrates, solvates and N-oxides thereof. The invention also provides pharmaceutical compositions that include such compounds as well as methods for making and methods for using such compounds in medical therapy.
• [EN] ANESTHETIC COMPOUNDS<br/>[FR] COMPOSÉS ANESTHÉSIQUES
  申请人：PHARMACOFORE INC

  公开号：WO2008011539A2

  公开（公告）日：2008-01-24

  [EN] In one embodiment the invention provides novel compounds of Formula (I) as well as prodrugs, salts, hydrates, solvates and N-oxides thereof. The invention also provides pharmaceutical compositions that include such compounds as well as methods for making and methods for using such compounds in medical therapy.
  [FR] Selon un de ses modes de réalisation, la présente invention concerne des composés innovants de formule (I) de même que des promédicaments, des sels, des hydrates, des solvates et des N-oxydes de ceux-ci. L'invention concerne également des compositions pharmaceutiques qui incluent de tels composés ainsi que des procédés de fabrication et d'utilisation de tels composés dans des traitements médicaux.
• β-DIETHYLAMINOETHYL ESTERS OF STERICALLY HINDERED ALKYL SUBSTITUTED BENZOIC ACIDS
  作者：NORMAN RABJOHN、J. W. FRONABARGER、W. W. LINSTROMBERG

  DOI：10.1021/jo01120a019

  日期：1955.2