4-(4-hydroxybenzoyl)-2,6-di(t-butyl)phenol | 69451-10-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(4-hydroxybenzoyl)-2,6-di(t-butyl)phenol
• 英文别名: (3,5-ditert-butyl-4-hydroxyphenyl)-(4-hydroxyphenyl)methanone
• CAS: 69451-10-1
• 化学式: C₂₁H₂₆O₃
• 分子量: 326.436
• InChiKey: YYMUFSLFPSYEQW-UHFFFAOYSA-N

物化性质

• 沸点：
  464.7±45.0 °C(Predicted)
• 密度：
  1.096±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  在 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 以 甲醇 为溶剂， 以93 %的产率得到4-(4-hydroxybenzoyl)-2,6-di(t-butyl)phenol
  参考文献：
  名称：

  A single-pot synthesis of 4-hydroxybenzophenones via acid-catalyzed alkoxylation of p-quinone methides followed by DDQ-assisted oxo-demethoxylation

  摘要：

  利用容易获得的 Amberlyst-15 和 DDQ 辅助氧代去甲氧基化对 QMs 进行烷氧基化，建立了一种单锅两步法，可在室温下合成高价值的 4-羟基二苯甲酮（81-99%）。

  DOI：

  10.1039/d3nj03163b

文献信息

• Anti-inflammatory method
  申请人：Riker Laboratories, Inc.

  公开号：US04124725A1

  公开（公告）日：1978-11-07

  Compounds in which 2,6-di(t-butyl)phenol is substituted in the 4 position by an optionally substituted benzoyl group have valuable pharmacological activity as anti-inflammatory agents.

  在化合物中，2,6-二（叔丁基）苯酚在4位被一个可选取代的苯甲酰基所取代，具有重要的药理活性，可作为抗炎药物。
• Antiallergic agents
  申请人：RIKER LABORATORIES, INCORPORATED

  公开号：EP0211548B1

  公开（公告）日：1990-05-09
• Stabilized polyolefin compositions
  申请人：Kumar Vijayendra

  公开号：US20070149660A1

  公开（公告）日：2007-06-28

  Disclosed are compositions comprising antioxidants and stabilizers, such as, acid scavengers or organic phosphorus stabilizers, and optionally further comprising co-stabilizers. The disclosed compositions are useful as stabilizers for polyolefins and other polymeric materials. The disclosed compositions and methods generally provide longer shelf lifes and better oxidative resistance to materials than currently available antioxidants.
• Lubricant oil compositions
  申请人：Cholli L. Ashok

  公开号：US20070161522A1

  公开（公告）日：2007-07-12

  Compositions comprise first antioxidants and first additives, such as, a surface additives, performance enhancing additives and lubricant protective additives and optionally second additives and/or second antioxidants. The compositions are useful to improve lubricants, lubricant oils and other lubricant materials. The compositions and methods generally provide longer shelf lives, increased oxidative resistance, improved quality and/or enhanced performance to lubricants or lubricant oils.
• Anti-oxidant macromonomers and polymers and methods of making and using the same
  申请人：Cholli Ashok L.

  公开号：US20080311065A1

  公开（公告）日：2008-12-18

  The present invention relates to macromonomer compounds possessing antioxidant properties, antioxidant polymers comprising the antioxidant macromonomers as a recurring unit, and methods of inhibiting oxidation in a substance comprising contacting the substance with the antioxidant polymers. In one embodiment, substantially all of the recurring macromonomeric units of the antioxidant polymers comprise an antioxidant moiety. In another embodiment, all of the recurring macromonomer units of the antioxidant polymers comprise an antioxidant moiety. The method of the present invention, yields antioxidant polymers with substantially all of the recurring units comprising an antioxidant moiety. These antioxidant polymers have greater bulk antioxidative properties than previously known.