N,N-dimethyloctan-2-amine | 7378-97-4

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N-dimethyloctan-2-amine
• 英文别名: Dimethyl(2-octyl)amine
• CAS: 7378-97-4
• 化学式: C₁₀H₂₃N
• 分子量: 157.299
• InChiKey: JXXZVUDFXQNPRZ-UHFFFAOYSA-N

物化性质

• 沸点：
  78 °C(Press: 18 Torr)
• 密度：
  0.778 g/cm3(Temp: 17 °C)
• 保留指数：
  1083

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N,N-dimethyloctan-2-amine 在 sodium hydroxide 作用下， 以 乙腈 为溶剂， 生成 anhydro
  参考文献：
  名称：

  涉及叶立德中间体的碱催化重排。第8部分。稳定的酰化铵的制备及一些反应

  摘要：

  羰基稳定的铵化铵（3），（12a–n）和（14a–c）是由相应的卤化铵（1），（13a–n）和（15a–c）与钠反应制得的在水或甲醇水溶液中的氢氧化物。由其分子式和光谱性质表征的叶立德在用氢溴酸处理后再生了季铵溴化物。通常，铵盐的反应类似于相应的the盐的反应。因此，具有适当迁移基团的亚烷基（ArCH 2）在加热下进行史蒂文斯[1,2]重排，以及其他酰基片段断裂，得到叔胺和含有PhCOCH基团的产物。许多酰化物与乙炔二甲酸二甲酯反应生成呋喃（32）。具有异氰酸苯酯的酰化物（14b和c）得到苯基氨基甲酰基取代的酰化物（35）。

  DOI：

  10.1039/p19810001154
• 作为产物：
  描述：

  二甲胺 、 仲辛酮 在 氢气 作用下， 以 甲醇 为溶剂， 50.0~80.0 ℃ 、1.5 MPa 条件下， 以97%的产率得到N,N-dimethyloctan-2-amine
  参考文献：
  名称：

  [EN] CATALYST, PREPARATION METHOD THEREFOR AND USE THEREOF
  [FR] CATALYSEUR, PROCÉDÉ DE PRÉPARATION ASSOCIÉ ET UTILISATION ASSOCIÉE

  摘要：

  The present invention relates to a catalyst, a preparation method therefor and use thereof, and belongs to the field of catalysts. The catalyst comprises a metal-based active component and a surface metal oxide active component, wherein the metal-based active component comprises at least one of a nickel-based catalyst or a cobalt-based catalyst, and the surface metal oxide active component comprises at least one of a tungsten oxide or a molybdenum oxide deposited on a surface of the metal-based active component. The catalyst may be used for the preparation of a multi-stage amine, which is simple to operate. The catalyst has a high activity in the reductive amination reaction, high safety, high selectivity and good stability; the catalyst can be repeatedly used many times; the catalyst is also beneficial to improving the quality and the quality stability of products and reducing the process cost; moreover, the catalyst has low modification cost, which is beneficial to large-scale production.

  公开号：

  WO2024027109A1

文献信息

• Efficient and Versatile Catalytic Systems for the N-Methylation of Primary Amines with Methanol Catalyzed by N-Heterocyclic Carbene Complexes of Iridium
  作者：Ken-ichi Fujita、Genki Toyooka、Akiko Tuji

  DOI：10.1055/s-0037-1610252

  日期：2018.12

  an appropriate catalyst). These findings can be used to develop methods for synthesizing useful amine compounds having N-methyl or N,N-dimethyl moieties. Efficient and versatile catalytic systems were developed for the N-methylation of both aliphatic and aromatic primary amines using methanol as the methylating agent. Iridium complexes bearing an N-heterocyclic carbene (NHC) ligand exhibited high catalytic

  摘要 使用甲醇作为甲基化剂，开发了用于脂肪族和芳香族伯胺的N-甲基化的高效通用催化体系。带有N-杂环卡宾（NHC）配体的铱配合物对这种类型的转化表现出高催化性能。对于脂族胺，在低温（50–90°C）下实现了选择性的N，N-二甲基化。对于芳族胺，选择性N-单甲基化和选择性N，N通过简单地改变反应条件（用合适的催化剂存在或不存在碱）来完成-二甲基化。这些发现可用于开发合成具有N-甲基或N，N-二甲基部分的有用的胺化合物的方法。 使用甲醇作为甲基化剂，开发了用于脂肪族和芳香族伯胺的N-甲基化的高效通用催化体系。带有N-杂环卡宾（NHC）配体的铱配合物对这种类型的转化表现出高催化性能。对于脂族胺，在低温（50–90°C）下实现了选择性的N，N-二甲基化。对于芳族胺，选择性N-单甲基化和选择性N，N通过简单地改变反应条件（用合适的催化剂存在或不存在碱）来完成-二甲基化。这些发现可用于开发合成具有N-
• Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins
  申请人：——

  公开号：US20030013913A1

  公开（公告）日：2003-01-16

  The invention relates to a chemical compound of formula (I), wherein M 1 represents an element selected from main groups II, III or IV of the periodic table of elements; x is equal to 1, 2, 3 or 4; y is equal to 2, 3 or 4, and; A represents a cation of main group V of the periodic table of elements; R 1 is the same or different and represents a branched or unbranched linear or cyclic C 1 -C 40 group that contains carbon; R 2 is the same or different and represents a branched or unbranched linear or cyclic C 1 -C 40 group that contains carbon; R 3 represents a branched or unbranched linear or cyclic C 1 -C 40 group that contains carbon, and; R 4 represents a hydrogen atom; whereby R 2 and R 3 are always different from one another.

  本发明涉及一种化学式（I）的化合物，其中M1代表元素，所选自元素周期表的主要II、III或IV族；x等于1、2、3或4；y等于2、3或4，并且A代表元素周期表的主要V族的阳离子；R1相同或不同，代表含有碳的支链或直链线性或环状C1-C40基团；R2相同或不同，代表含有碳的支链或直链线性或环状C1-C40基团；R3代表含有碳的支链或直链线性或环状C1-C40基团，且R4代表氢原子；其中R2和R3始终彼此不同。
• Ims detection of chemical markers in petroleum products
  申请人：Authentix, Inc.

  公开号：EP2264130A2

  公开（公告）日：2010-12-22

  A method and composition for identifying chemically tagged petroleum products can be achieved by adding one or more chemicals to a selected petroleum product wherein the chemical is immune to extraction from the petroleum product by conventional inexpensive absorbents, cannot be removed by extraction with acids, bases, or immiscible solvents, cannot be easily oxidized, reduced or reacted with common agents, is difficult to disguise by masking with other agents, has a low polarity, and has a boiling pint in the range of the petroleum product the chemical is being added to. The presence of the chemical is determined by using ion mobility to spectroscopy.

  通过向选定的石油产品中添加一种或多种化学物质，可以实现识别化学标记石油产品的方法和组合物，其中的化学物质不会被传统的廉价吸收剂从石油产品中萃取出来，不能被酸、碱或不溶性溶剂萃取去除，不容易被氧化、还原或与普通制剂发生反应，难以用其他制剂掩盖，极性低，沸点在所添加化学物质的石油产品范围内。化学品的存在是通过离子迁移率和光谱来确定的。
• PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF
  申请人：Qingdao KingAgroot Chemical Compound Co., Ltd.

  公开号：EP3747870A1

  公开（公告）日：2020-12-09

  The invention belongs to the technical field of agricultural chemicals, and in particular relates to a pyridazinol compound represented by the Formula I, a derivative, preparation method, herbicidal composition and use thereof. The compound, derivative and herbicidal composition thereof have very high herbicidal activity and selectivity, and are safe for crops,

  本发明属于农药技术领域，尤其涉及一种由式 I 表示的哒嗪类化合物、其衍生物、制备方法、除草组合物及其用途。本发明的化合物、衍生物和除草组合物具有极高的除草活性和选择性，对作物安全、
• Pyrido[3, 4-d]pyrimidine derivative and pharmaceutically acceptable salt thereof
  申请人：Teijin Pharma Limited

  公开号：US11084814B2

  公开（公告）日：2021-08-10

  The purpose of the present invention is to provide a compound that has excellent CDK4/6 inhibitory activity. The present invention is a compound represented by formula (I) or a pharmaceutically acceptable salt of the compound.

  本发明的目的是提供一种具有优异 CDK4/6 抑制活性的化合物。本发明是一种由式（I）代表的化合物或该化合物的药学上可接受的盐。