N-[2,2,2-trichloro-1-(phenylsulfonylamino)ethyl]ethanedithioamide | 1257096-40-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[2,2,2-trichloro-1-(phenylsulfonylamino)ethyl]ethanedithioamide
• 英文别名: N-[2,2,2-trichloro-1-(phenylsulfonylamino)-ethyl]ethanedithioamide；N'-[1-(benzenesulfonamido)-2,2,2-trichloroethyl]ethanedithioamide
• CAS: 1257096-40-4
• 化学式: C₁₀H₁₀Cl₃N₃O₂S₃
• 分子量: 406.765
• InChiKey: ATCIAHKPVQPHEG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  157
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  N-(2,2,2-trichloroethylidene)benzenesulfonamide 、 二硫代乙酰胺 以 N,N-二甲基甲酰胺 为溶剂， 反应 12.0h， 以81%的产率得到N-[2,2,2-trichloro-1-(phenylsulfonylamino)ethyl]ethanedithioamide
  参考文献：
  名称：

  Functionalization of highly electrophilic N-(2,2,2-trichloroethylidene)- and N-(2,2-dichloro-2-phenylethylidene) arenesulfonamides with dithiooxamide

  摘要：

  Depending on the reactant ratio, dithiooxamide (ethanedithioamide) reacted as N-nucleophile or N,N'-binucleophile with highly electrophilic aldimines, N-(2,2,2-trichloroethylidene)- and N-(2,2-dichloro-2-phenylethylidene)arenesulfonamides, to give the corresponding mono- or bis-adducts, N-[2-polychloro-1-(arylsulfonylamino) ethyl]ethanedithioamides or N,N'-bis[2-polychloro-1-(arylsulfonylamino)ethyl]ethanedithioamides, in good yield.

  DOI：

  10.1134/s1070428012040021

文献信息

• Functionalization of highly electrophilic N-(2,2,2-trichloroethylidene)- and N-(2,2-dichloro-2-phenylethylidene) arenesulfonamides with dithiooxamide
  作者：G. N. Rozentsveig、A. I. Fedotova、V. Yu. Serykh、K. A. Chernyshev、I. B. Rozentsveig

  DOI：10.1134/s1070428012040021

  日期：2012.4

  Depending on the reactant ratio, dithiooxamide (ethanedithioamide) reacted as N-nucleophile or N,N'-binucleophile with highly electrophilic aldimines, N-(2,2,2-trichloroethylidene)- and N-(2,2-dichloro-2-phenylethylidene)arenesulfonamides, to give the corresponding mono- or bis-adducts, N-[2-polychloro-1-(arylsulfonylamino) ethyl]ethanedithioamides or N,N'-bis[2-polychloro-1-(arylsulfonylamino)ethyl]ethanedithioamides, in good yield.