N¹-(3,4-dimethoxybenzylidene)-N³,N³-dimethylpropan-1,3-diamine | 867313-09-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N¹-(3,4-dimethoxybenzylidene)-N³,N³-dimethylpropan-1,3-diamine
• 英文别名: N-(3,4-dimethoxybenzylidene)-N',N'-dimethyl-1,3-propanediamine；3-[(3,4-dimethoxyphenyl)methylideneamino]-N,N-dimethylpropan-1-amine
• CAS: 867313-09-5
• 化学式: C₁₄H₂₂N₂O₂
• 分子量: 250.341
• InChiKey: PALYKDJBDAXJRR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N¹-(3,4-dimethoxybenzylidene)-N³,N³-dimethylpropan-1,3-diamine 、 癸基溴 以 乙醇 为溶剂， 生成 N-((3-(3,4-dimethoxybenzylidene)amino)propyl)-N,N-dimethyldecan-1-ammonium bromide
  参考文献：
  名称：

  Surface and biological activity of N-(((dimethoxybenzylidene)amino)propyl)-N,N-dimethylalkyl-1-ammonium derivatives as cationic surfactants

  摘要：

  The colloidal and biological properties of three newly cationic surfactants were investigated. The chemical structure of the prepared cationic surfactants which formed through condensation reaction between dimethylaminopropylamine (DMAPA) and 3,4-dimethoxybenzaldehyde then quatemized by three fatty alkyl bromide was confirmed by FTIR, H-1 NMR and mass spectroscopy. Many important physiochemical parameters, such as the critical micelle concentration (CMC), maximum surface excess (T-max), minimum surface area (A(min)), efficiency (PC20) and effectiveness (pi(CMC)) have been determined utilizing surface tension. By increasing the hydrophobic chain length, the values of CMC Gamma(max), decrease while Amin value was increased. The thermodynamic parameters (Delta G degrees min and Delta G degrees ads) showed that adsorption and micellization processes are spontaneous. It is clear that the prepared cationic surfactants tend to adsorb at surface, then it aggregate to form micelle. The prepared surfactants showed good biological activity against Gram-positive and Gram-negative bacteria and fungi. (C) 2015 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molliq.2015.03.043
• 作为产物：
  描述：

  3,4-二甲氧基苯甲醛 、 N,N-二甲基-1,3-二氨基丙烷 以 乙醇 为溶剂， 反应 6.0h， 生成 N¹-(3,4-dimethoxybenzylidene)-N³,N³-dimethylpropan-1,3-diamine
  参考文献：
  名称：

  Surface and biological activity of N-(((dimethoxybenzylidene)amino)propyl)-N,N-dimethylalkyl-1-ammonium derivatives as cationic surfactants

  摘要：

  The colloidal and biological properties of three newly cationic surfactants were investigated. The chemical structure of the prepared cationic surfactants which formed through condensation reaction between dimethylaminopropylamine (DMAPA) and 3,4-dimethoxybenzaldehyde then quatemized by three fatty alkyl bromide was confirmed by FTIR, H-1 NMR and mass spectroscopy. Many important physiochemical parameters, such as the critical micelle concentration (CMC), maximum surface excess (T-max), minimum surface area (A(min)), efficiency (PC20) and effectiveness (pi(CMC)) have been determined utilizing surface tension. By increasing the hydrophobic chain length, the values of CMC Gamma(max), decrease while Amin value was increased. The thermodynamic parameters (Delta G degrees min and Delta G degrees ads) showed that adsorption and micellization processes are spontaneous. It is clear that the prepared cationic surfactants tend to adsorb at surface, then it aggregate to form micelle. The prepared surfactants showed good biological activity against Gram-positive and Gram-negative bacteria and fungi. (C) 2015 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molliq.2015.03.043

文献信息

• Synthesis and reactivity of cyclometallated platinum (II) compounds containing [C,N,N′] terdentate ligands: Crystal structures of [PtCl{(CH3)2N(CH2)3NCH(4-ClC 6H3)}], [PtCl{(CH3)2N(CH2)3NCH(2-ClC6H3)}] and [PtCl{(CH3)2N(CH2)3NCH(3-(CH3)C6H3)}]
  作者：Alejandro Capapé、Margarita Crespo、Jaume Granell、Mercè Font-Bardía、Xavier Solans

  DOI：10.1016/j.jorganchem.2005.06.038

  日期：2005.10

  The reaction of compound CiS-[PtCl2(dmos)(2)] With ligands RCHN(CH2)(3)NMe2 (1a-1h) in which R is a phenyl group containing substituents such as Cl, F, Me, NO2 and MeO produced compounds [PtCl2(CH3)(2)N(CH2)(3)NCHR}] (2), as mixtures of Z and E isomers. When treated with an equimolar amount of sodium acetate in refluxing methanol compounds 2 gave cyclometallated platinum compounds 3 containing a terdentate [C,N,N'] ligand. The obtained compounds were fully characterized including structure determinations for compounds 3a, 3b and 3e. The effects of the substituents in the regioselectivity of the cyclometallation reaction and the reactivity of 3a and 3b with mono and bidentate phosphines were also studied. (c) 2005 Elsevier B.V. All rights reserved.
• Surface and biological activity of N-(((dimethoxybenzylidene)amino)propyl)-N,N-dimethylalkyl-1-ammonium derivatives as cationic surfactants
  作者：Samy M. Shaban、Ismail Aiad、Mohamed M. El-Sukkary、E.A. Soliman、Moshira Y. El-Awady

  DOI：10.1016/j.molliq.2015.03.043

  日期：2015.7

  The colloidal and biological properties of three newly cationic surfactants were investigated. The chemical structure of the prepared cationic surfactants which formed through condensation reaction between dimethylaminopropylamine (DMAPA) and 3,4-dimethoxybenzaldehyde then quatemized by three fatty alkyl bromide was confirmed by FTIR, H-1 NMR and mass spectroscopy. Many important physiochemical parameters, such as the critical micelle concentration (CMC), maximum surface excess (T-max), minimum surface area (A(min)), efficiency (PC20) and effectiveness (pi(CMC)) have been determined utilizing surface tension. By increasing the hydrophobic chain length, the values of CMC Gamma(max), decrease while Amin value was increased. The thermodynamic parameters (Delta G degrees min and Delta G degrees ads) showed that adsorption and micellization processes are spontaneous. It is clear that the prepared cationic surfactants tend to adsorb at surface, then it aggregate to form micelle. The prepared surfactants showed good biological activity against Gram-positive and Gram-negative bacteria and fungi. (C) 2015 Elsevier B.V. All rights reserved.