3,5-Dichlorophenyl chloroformate | 128203-09-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3,5-Dichlorophenyl chloroformate
• 英文别名: (3,5-dichlorophenyl) carbonochloridate
• CAS: 128203-09-8
• 化学式: C₇H₃Cl₃O₂
• mdl: MFCD24141239
• 分子量: 225.459
• InChiKey: HRINFEIZZPVYIB-UHFFFAOYSA-N

物化性质

• 沸点：
  267.1±30.0 °C(Predicted)
• 密度：
  1.545±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3,5-Dichlorophenyl chloroformate 、 在 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 为溶剂， 以91%的产率得到(3,5-dichlorophenyl) N-[(3S,7S,11S)-7,11-bis[(3,5-dichlorophenoxy)carbonylamino]-2,6,10-trioxo-1,5,9-trioxacyclododec-3-yl]carbamate
  参考文献：
  名称：

  Carbamate triserine lactone receptors for anion recognition

  摘要：

  We have taken advantage of the ability of the cyclic triester of L-serine to organize ligand units appended to the three alpha-amine functionalities, as in enterobactin, a siderophore produced by enteric bacteria that binds ferric ion exceptionally well (K-f = 10(49)). As an extension of the preorganization concept, this work describes the preparation and characterization of carbamate triserine lactone receptors 1-6 and their ability to act as molecular receptors for anions. These receptors bind halides (F- >> Cl- > Br- > I-) with binding constants K in the range 21-7350 L mol(-1). (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.08.081
• 作为产物：
  描述：

  光气 、 3,5-二氯苯酚 在 N,N-二甲基苯胺 作用下， 以 甲苯 为溶剂， 以91%的产率得到3,5-Dichlorophenyl chloroformate
  参考文献：
  名称：

  Carbamate triserine lactone receptors for anion recognition

  摘要：

  We have taken advantage of the ability of the cyclic triester of L-serine to organize ligand units appended to the three alpha-amine functionalities, as in enterobactin, a siderophore produced by enteric bacteria that binds ferric ion exceptionally well (K-f = 10(49)). As an extension of the preorganization concept, this work describes the preparation and characterization of carbamate triserine lactone receptors 1-6 and their ability to act as molecular receptors for anions. These receptors bind halides (F- >> Cl- > Br- > I-) with binding constants K in the range 21-7350 L mol(-1). (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.08.081

文献信息

• TAKAXASI, DZYUNYA;YAMAMOTO, SIGEHO;TEHRAMAEH, TOMOXIRO
  作者：TAKAXASI, DZYUNYA、YAMAMOTO, SIGEHO、TEHRAMAEH, TOMOXIRO

  DOI：——

  日期：——
• Carbamate triserine lactone receptors for anion recognition
  作者：Yizhe Wang、Edward Duran、David Nacionales、Amber Valencia、Christopher Wostenberg、Eric R. Marinez

  DOI：10.1016/j.tetlet.2008.08.081

  日期：2008.11

  We have taken advantage of the ability of the cyclic triester of L-serine to organize ligand units appended to the three alpha-amine functionalities, as in enterobactin, a siderophore produced by enteric bacteria that binds ferric ion exceptionally well (K-f = 10(49)). As an extension of the preorganization concept, this work describes the preparation and characterization of carbamate triserine lactone receptors 1-6 and their ability to act as molecular receptors for anions. These receptors bind halides (F- >> Cl- > Br- > I-) with binding constants K in the range 21-7350 L mol(-1). (C) 2008 Elsevier Ltd. All rights reserved.