N5-(6-(dimethylamino)pyridin-3-yl)-N2,N2-dimethylpyridine-2,5-diamine | 1362243-16-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N5-(6-(dimethylamino)pyridin-3-yl)-N2,N2-dimethylpyridine-2,5-diamine
• 英文别名: 5-N-[6-(dimethylamino)pyridin-3-yl]-2-N,2-N-dimethylpyridine-2,5-diamine
• CAS: 1362243-16-0
• 化学式: C₁₄H₁₉N₅
• 分子量: 257.338
• InChiKey: XELQQUVVACIQRE-UHFFFAOYSA-N

物化性质

• 沸点：
  445.1±45.0 °C(Predicted)
• 密度：
  1.180±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  44.3
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  N5-(6-(dimethylamino)pyridin-3-yl)-N2,N2-dimethylpyridine-2,5-diamine 在 peroxyl radical 作用下， 以 氯苯 为溶剂， 生成
  参考文献：
  名称：

  Incorporation of Ring Nitrogens into Diphenylamine Antioxidants: Striking a Balance between Reactivity and Stability

  摘要：

  The incorporation of nitrogen atoms into the aryl rings of conventional diphenylamine antioxidants enables the preparation of readily accessible, air-stable analogues, several of which have temperature-independent radical-trapping activities up to 200-fold greater than those of typical commercial diphenylamines. Amazingly, the nitrogen atoms raise the oxidation potentials of the amines without greatly changing their radical-trapping (H-atom transfer) reactivity.

  DOI：

  10.1021/ja300086z
• 作为产物：
  描述：

  5-溴-2-二甲基氨基吡啶 、 N,N-二甲基吡啶-2,5-二胺 生成 N5-(6-(dimethylamino)pyridin-3-yl)-N2,N2-dimethylpyridine-2,5-diamine
  参考文献：
  名称：

  Substituted Diarylamines and Use of Same as Antioxidants

  摘要：

  公式I、公式IA、公式IB或公式II的化合物或其酸或碱盐的混合物，并将这些化合物用作抗氧化剂。在一个实施例中，化合物为公式II，其中X、Y和Z分别独立地为碳或氮原子；R1和R2分别独立地为氢或电子给体基团，但不是两个都是氢，并且R1和R2分别与它们自己的芳香环上的碳原子相结合。

  公开号：

  US20140206585A1

文献信息

• [EN] SUBSTITUTED DIARYLAMINES AND USE OF SAME AS ANTIOXIDANTS<br/>[FR] DIARYLAMINES SUBSTITUÉES ET UTILISATION DE CELLES-CI EN TANT QU'ANTIOXYDANTS
  申请人：UNIV KINGSTON

  公开号：WO2012162818A1

  公开（公告）日：2012-12-06

  The present invention relates to substituted heteroaromatic dianlamine compounds of Formula I and II, their pharmaceutically acceptable salts, and compositions thereof useful as antioxidants, wherein each of X, Y and Z are independently a carbon or nitrogen atom; R1 and R2 are each independently a hydrogen or an electron donating group, but are not both hydrogen, and wherein R1 and R2 are each bonded to a carbon atom in their own respective aryl ring.

  本发明涉及Formula I和II的替代杂环二胺化合物，它们的药用盐以及作为抗氧化剂有用的组合物，其中X、Y和Z中的每一个都是独立的碳或氮原子；R1和R2分别是氢或电子给体基团，但两者不都是氢，并且R1和R2分别与它们自己各自的芳香环中的碳原子结合。
• Substituted Diarylamines and Use of Same as Antioxidants
  申请人：Pratt Derek A.

  公开号：US20140206585A1

  公开（公告）日：2014-07-24

  A compound of Formula I, Formula IA, Formula IB, or Formula II, or an acid or base addition salt thereof, and use of these compounds as antioxidants. In one embodiment, a compound of Formula II, wherein each of X, Y, and Z are independently a carbon or nitrogen atom; R 1 and R 2 are each independently a hydrogen or an electron donating group, but are not both hydrogen, and wherein R 1 , and R 2 are each bonded to a carbon atom in their own respective aryl ring.

  公式I、公式IA、公式IB或公式II的化合物或其酸或碱盐的混合物，并将这些化合物用作抗氧化剂。在一个实施例中，化合物为公式II，其中X、Y和Z分别独立地为碳或氮原子；R1和R2分别独立地为氢或电子给体基团，但不是两个都是氢，并且R1和R2分别与它们自己的芳香环上的碳原子相结合。
• Leuco colorants as bluing agents in laundry care compositions
  申请人：The Procter & Gamble Company

  公开号：US11136535B2

  公开（公告）日：2021-10-05

  A laundry care composition comprising: (a) at least one laundry care ingredient, (b) a leuco composition; (c) a stabilizing amount of an antioxidant composition which comprises at least one phenol selected from the group consisting of alkylated phenol, hindered phenol, and mixtures thereof and at least one substituted diarylamine, wherein the mole ratio of the phenol to the substituted diarylamine is greater than 1:1.

  一种衣物护理组合物，包括：(a) 至少一种衣物护理成分；(b) 一种洗衣剂组合物；(c) 一种稳定量的抗氧化剂组合物，该抗氧化剂组合物包括至少一种选自烷基化苯酚、受阻苯酚及其混合物的苯酚和至少一种取代的二芳基胺，其中苯酚与取代的二芳基胺的摩尔比大于 1:1。
• Stabilized compositions comprising leuco compounds
  申请人：Milliken & Company

  公开号：US11261403B2

  公开（公告）日：2022-03-01

  A composition comprising: (a) a leuco composition; and (b) a stabilizing amount of an antioxidant composition. The antioxidant composition comprises at least one sterically hindered phenol and at least one substituted diarylamine, and the mole ratio of the hindered phenol to the substituted diarylamine is greater than 1:1. In another embodiment, a composition comprises (a) a leuco composition and (b) an antioxidant composition; and optionally (c) a solvent composition. The combined mass of the leuco compounds and antioxidants present in the composition is 10% or more of the total mass of the composition, and (b) the molar ratio of antioxidants present in the composition to leuco compounds present in the composition is greater than 1:1.

  一种组合物，包括：(a)一种白蛋白组合物；和(b)一种稳定量的抗氧化剂组合物。抗氧化剂组合物包括至少一种立体受阻酚和至少一种取代的二芳基胺，受阻酚与取代的二芳基胺的摩尔比大于 1:1。在另一个实施方案中，组合物包括：(a) 白亮组合物和 (b) 抗氧化剂组合物；以及 (c) 溶剂组合物。组合物中存在的月桂化合物和抗氧化剂的总质量占组合物总质量的 10%或以上，且(b) 组合物中存在的抗氧化剂与组合物中存在的月桂化合物的摩尔比大于 1:1。
• LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS
  申请人：The Procter & Gamble Company

  公开号：EP3830232A1

  公开（公告）日：2021-06-09