3-Hydroxymethyl-alizarin | 22296-60-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 3-Hydroxymethyl-alizarin
• 英文别名: 1,2-Dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione
• CAS: 22296-60-2
• 化学式: C₁₅H₁₀O₅
• 分子量: 270.241
• InChiKey: MJWOLCKCMOQXJR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  94.8
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• [EN] PRODUCTION OF RHEIN AND RHEIN DERIVATIVES<br/>[FR] PRODUCTION DE RHEINE ET DE SES DERIVES
  申请人：WISCONSIN ALUMNI RESEARCH FOUNDATION

  公开号：WO1996030034A1

  公开（公告）日：1996-10-03

  (EN) Methods for the production of rhein and rhein derivatives from aloin-containing substances are described. The oxidation of aloe yellow sap to form aloe-emodin is described, as are the further steps used to treat aloe-emodin to form rhein or rhein derivatives. The present invention provides for the production of rhein and rhein derivatives by methods that are more efficient and economical than those used previously.(FR) La présente invention décrit des méthodes de fabrication de la rhéine et de ses dérivés à partir de substances contenant de l'aloïne. L'invention décrit l'oxydation de la sève jaune de l'aloès pour former de l'émodine d'aloès. La présente invention se rapporte à des méthodes de production de rhéine et de ses dérivés plus efficaces et plus économiques que celles utilisées auparavant.

  （ZH）本文描述了从含有大黄素的物质中生产大黄素及其衍生物的方法。描述了将芦荟黄汁氧化成芦荟大黄素的步骤，以及用于处理芦荟大黄素以形成大黄素或其衍生物的进一步步骤。本发明提供了比先前使用的方法更高效和经济的生产大黄素及其衍生物的方法。
• ANTI-VIRAL PROPERTIES OF ALOE VERA AND ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS) TREATMENT
  申请人：North Texas Medical Associates

  公开号：EP2595643A1

  公开（公告）日：2013-05-29
• [EN] ANTI-VIRAL PROPERTIES OF ALOE VERA AND ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS) TREATMENT<br/>[FR] PROPRIÉTÉS ANTIVIRALES DE L'ALOÈS ET TRAITEMENT DU SYNDROME D'IMMUNODÉFICIENCE ACQUISE (SIDA)
  申请人：NORTH TEXAS MEDICAL ASS

  公开号：WO2012012513A1

  公开（公告）日：2012-01-26

  A pharmaceutical composition comprising a combination of formulations derived from Aloe vera for the treatment of Acquired Immune Deficiency Syndrome (AIDS) or HIV infection is described herein. The composition comprises: (i) an injectable sterile polymannan extract, (ii) Raidox (aloe anthraquinones and their diacetyl derivatives), and (iii) a freeze dried aloe vera powder, aloe vera juice, aloe gel or a combination. In addition one or more nutritional supplements comprising fatty acids, proteins, minerals and metals, vitamins, salts, amino acids, and other pharmaceutically acceptable excipients may also be include to counteract the chronic diarrhea, digestive upsets, and weight loss seen in some patients before and during the treatment course. A method for treating the AIDS or HIV infection using the composition of the present invention is also disclosed.