bis-(3-tert-butyl-4-hydroxyphenyl)sulfide | 7566-50-9

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: bis-(3-tert-butyl-4-hydroxyphenyl)sulfide
• 英文别名: 4,4'-thiobis[2-bis(tert-butyl)phenol]；GRI 387297；4,4'-Thiobis(2-tert-butylphenol)；2-tert-butyl-4-(3-tert-butyl-4-hydroxyphenyl)sulfanylphenol
• CAS: 7566-50-9
• 化学式: C₂₀H₂₆O₂S
• 分子量: 330.491
• InChiKey: XHALKWMTKWHQLO-UHFFFAOYSA-N

物化性质

• 熔点：
  105-110 °C
• 沸点：
  484.4±45.0 °C(Predicted)
• 密度：
  1.14±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  65.8
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  bis-(3-tert-butyl-4-hydroxyphenyl)sulfide 、 N-BOC-GAMMA-氨基丁酸 在 4-二甲氨基吡啶 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以172 mg的产率得到2-tert-butyl-4-(3-tert-butyl-4-hydroxyphenylthio)-phenyl 4-(tert-butoxycarbonylamino)butanoate
  参考文献：
  名称：

  酵母高丝氨酸脱氢酶的新型酚类抑制剂。

  摘要：

  抗菌剂相对未开发的潜在靶标是必需氨基酸的生物合成。在NAD（P）H依赖性反应中将天冬氨酸半醛还原为高丝氨酸的高丝氨酸脱氢酶是从Asp生物合成Met，Thr和Ile所需的此类靶标之一。我们报告了酵母高丝氨酸脱氢酶的小分子筛查，该酶已鉴定出该类酶的新型酚类抑制剂。与高丝氨酸脱氢酶复合的抑制剂之一的X射线晶体结构分析表明，这些分子在活性位点的氨基酸结合区域结合，酚羟基与Gly175的主链酰胺特异性相互作用。

  DOI：

  10.1016/j.bmc.2004.05.009
• 作为产物：
  描述：

  2-叔丁基苯酚 在 二氯化硫 作用下， 以 甲苯 为溶剂， 反应 3.0h， 以47%的产率得到bis-(3-tert-butyl-4-hydroxyphenyl)sulfide
  参考文献：
  名称：

  Synthesis, composition, and properties of products formed in interaction of ortho-tert-butylphenol with sulfur monochloride

  摘要：

  Interaction of ortho-tert-butylphenol with sulfur monochloride in dimethylformamide leads to an increase in the fraction of phenol di- and polysulfides in the product. Liquid chromato-mass-spectrometry was used to determine the composition of the main groups of compounds contained in the mixture. A number of its components was isolated and produced by counter synthesis.

  DOI：

  10.1134/s1070427209110123

文献信息

• [EN] COLOUR CHANGE COMPOSITION AND COMPOUNDS<br/>[FR] COMPOSITION DE CHANGEMENT DE COULEUR ET COMPOSÉS
  申请人：THERMOGRAPHIC MEASUREMENTS LTD

  公开号：WO2021019074A1

  公开（公告）日：2021-02-04

  The invention provides a colour change composition containing an electron donating organic colouring compound, an electron accepting compound and a compound of formula (I): wherein E is an ester linkage O-CO or -CO2, R is independently selected from an optionally substituted linear or branched alkyl group, alkenyl cycloalkyl group, alkenyl group, alkoxy group, aryl and alkylene aryl group having from 6 to 22 carbon atoms; Y1 Y2 X1 and X2 are independently selected from hydrogen, R', -OR' and halogen; wherein R' is independently selected from an optionally substituted linear or branched alkyl group, alkenyl group, alkoxy group, aryl group and an alkylene aryl group; having from 5 to 22 carbon atoms; r and p each represent and integer from 0 to 3. The compound of formula (I) and compositions of the invention are useful in providing a colour change effect, in memory compositions and visual indicators, particularly in security and healthcare applications.

  本发明提供了一种颜色变化组合物，其包含一个电子供体有机染色化合物，一个电子受体化合物和一个式子（I）的化合物： 其中，E是酯键O-CO或-CO2，R是独立选择的可选取代的线性或支链烷基，烯基环烷基，烯基基团，烷氧基，芳基和具有6到22个碳原子的烷基芳基基团；Y1，Y2，X1和X2独立选择自氢，R'，-OR'和卤素；其中，R'是独立选择的可选取代的线性或支链烷基，烯基基团，烷氧基，芳基和具有5到22个碳原子的烷基芳基基团；r和p各代表0到3的整数。式（I）的化合物和本发明的组合物在提供颜色变化效果，存储组合物和视觉指示器，特别是在安全和医疗应用中非常有用。
• PHENOL-FREE PHOSPHITES DERIVATIVES AND PREPARATION THEREOF
  申请人：HUANG Kuang Hsu

  公开号：US20130090491A1

  公开（公告）日：2013-04-11

  The present invention relates to phenol-free phosphites and preparation thereof. The phenol-free phosphites are obtained by reacting biphenol, and phosphorous derivatives with higher aliphatic alcohol via condensation and trans-esterification. The phenol-free phosphites of the present invention can be used as a heat stabilizer for resin so as to enhance the heat resistance of the resin during processing at high temperatures.

  本发明涉及无酚磷酸酯及其制备方法。所述无酚磷酸酯是通过联缩和酯交换反应将联苯酚和磷酸衍生物与高级脂肪醇反应得到的。本发明的无酚磷酸酯可用作树脂的热稳定剂，以增强树脂在高温加工过程中的耐热性。
• Modified ethylene-vinyl alcohol copolymer and method for the production thereof
  申请人：——

  公开号：US20040096683A1

  公开（公告）日：2004-05-20

  Provided is a modified ethylene-vinyl alcohol copolymer (C) having an ethylen content of 5 to 55 mol %, which contains a specific structural unit (I) in an amount of 0.3 to 40 mol % and may be obtained by reacting an ethylene-vinyl alcohol copolymer (A) with a monofunctional epoxy compound (B) having a molecular weight of not more than 500. This can be produced by a method for producing the modified ethylene-vinyl alcohol copolymer (C) which comprises melting and kneading an ethylene-vinyl alcohol copolymer (A) with a monofunctional epoxy compound (B) in an extruder. The modified ethylene-vinyl alcohol copolymer (C) is superior to a unmodified ethylene-vinyl alcohol copolymer (A) in transparency, stretchability, flexibility and flexing resistance due to the specific structural unit (I) incorporated therein, and thus, can be used as a barrier material in various applications requiring the above performance capabilities.

  提供的是一种改性乙烯-醋酸乙烯共聚物(C)，其乙烯含量为5至55摩尔％，其中含有一种特定的结构单元(I)，其含量为0.3至40摩尔％，可通过将乙烯-醋酸乙烯共聚物(A)与分子量不超过500的单官能环氧化合物(B)反应而获得。该改性乙烯-醋酸乙烯共聚物(C)的制备方法包括在挤出机中熔融和揉捏乙烯-醋酸乙烯共聚物(A)与单官能环氧化合物(B)。由于其中包含了特定的结构单元(I)，改性乙烯-醋酸乙烯共聚物(C)在透明度、可伸展性、柔韧性和耐弯曲性方面优于未改性的乙烯-醋酸乙烯共聚物(A)，因此可以用作在需要上述性能能力的各种应用中的障壁材料。
• Resin composition and multi-layer structures
  申请人：Tai Shinji

  公开号：US20050147778A1

  公开（公告）日：2005-07-07

  Provided is a resin composition comprising 1-99% by weight of a modified ethylene-vinyl alcohol copolymer (C) having an ethylene content of 5-55 mol %, which contains a specific structural unit (I) in an amount of 0.3-40 mol % and can be obtained by reacting an ethylene-vinyl alcohol copolymer (A) with a monofunctional epoxy compound (B) having a molecular weight of not more than 500, and 1-99% by weight of a thermoplastic resin (T 1 ) other than (C). Moreover, a multilayer structure in which the resin composition and a thermoplastic resin (T 2 ) are laminated is also provided. Thus, a resin composition superior in barrier properties, transparency, stretchability, flexibility, flexing resistance and interlayer adhesiveness and various kinds of molded articles made thereof are provided.

  本发明提供了一种树脂组合物，包括重量百分比为1-99%的改性乙烯-醇酸共聚物(C)，该共聚物的乙烯含量为5-55摩尔％，其中含有特定的结构单元(I)，其含量为0.3-40摩尔％，可以通过将乙烯-醇酸共聚物(A)与分子量不超过500的单官能环氧化合物(B)反应而获得，以及重量百分比为1-99%的热塑性树脂(T1)，该树脂组合物和热塑性树脂(T2)层压形成多层结构。因此，提供了一种优异的阻隔性、透明性、可拉伸性、柔韧性、耐弯曲性和层间粘附性的树脂组合物及其各种成型制品。
• Oxygen absorption resin composition
  申请人：Tsuji Yoshihisa

  公开号：US20050153087A1

  公开（公告）日：2005-07-14

  An oxygen absorption resin composition is provided that comprises a thermoplastic resin (A) having carbon-carbon double bonds substantially in its main chain and a transition metal salt (B). If necessary, the composition further comprises a gas barrier resin (C), a compatibilizer (D) and the like. The composition has excellent oxygen absorption properties, and when the composition is employed, generation of odorous substances derived from the decomposition of resins as a result of oxygen absorption can be suppressed.

  提供了一种含有热塑性树脂（A）和过渡金属盐（B）的氧吸收树脂组合物。必要时，该组合物还包括气体障壁树脂（C）、相容剂（D）等。该组合物具有优异的氧吸收性能，当使用该组合物时，可以抑制由于氧吸收引起的树脂分解产生的异味物质的生成。