S-(4-bromophenyl) 4-fluorobenzenesulfonothioate | 1415245-44-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: S-(4-bromophenyl) 4-fluorobenzenesulfonothioate
• 英文别名: 1-(4-Bromophenyl)sulfanylsulfonyl-4-fluorobenzene；1-(4-bromophenyl)sulfanylsulfonyl-4-fluorobenzene
• CAS: 1415245-44-1
• 化学式: C₁₂H₈BrFO₂S₂
• 分子量: 347.229
• InChiKey: XXIJASYXELGDEJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  67.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1-((4-bromophenyl)thio)pyrrolidine-2,5-dione 、 sodium 4-fluorobenzenesulfinate 在 scandium tris(trifluoromethanesulfonate) 作用下， 以 水 为溶剂， 反应 2.0h， 以73%的产率得到S-(4-bromophenyl) 4-fluorobenzenesulfonothioate
  参考文献：
  名称：

  Sc(OTf)3-catalyzed synthesis of thiosulfonates in ionic liquid-water

  摘要：

  The first example of Sc(OTf)(3)-catalyzed sulfenylation of sodium sulfinates with N-(organothio)succinimides in ionic liquids (ILs) and water cosolvent system was developed, achieving thiosulfonates in moderate to excellent yields. Additionally, Sc(OTf)(3)/ILs could be recovered easily after the reactions and reused without a significant loss in the catalytic activity. Thus, the present protocol represents an interesting complement to known methods for thiosulfonates synthesis. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.09.132

文献信息

• Sc(OTf)3-catalyzed synthesis of thiosulfonates in ionic liquid-water
  作者：Gaigai Liang、Jing Chen、Jiali Chen、Wanmei Li、Jiuxi Chen、Huayue Wu

  DOI：10.1016/j.tetlet.2012.09.132

  日期：2012.12

  The first example of Sc(OTf)(3)-catalyzed sulfenylation of sodium sulfinates with N-(organothio)succinimides in ionic liquids (ILs) and water cosolvent system was developed, achieving thiosulfonates in moderate to excellent yields. Additionally, Sc(OTf)(3)/ILs could be recovered easily after the reactions and reused without a significant loss in the catalytic activity. Thus, the present protocol represents an interesting complement to known methods for thiosulfonates synthesis. (C) 2012 Elsevier Ltd. All rights reserved.